NOMO2 and EXOSC10

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		NOMO2	EXOSC10
Gene Name		NODAL modulator 2	exosome component 10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Transcriptionally Active Chromatin
	Molecular Function	Protein Binding Carbohydrate Binding	Nucleotide Binding Exoribonuclease Activity Protein Binding 3'-5' Exonuclease Activity Poly(A) RNA Binding
	Biological Process		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of 5.8S RRNA Nuclear-transcribed MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Nuclear MRNA Surveillance CUT Catabolic Process Nuclear Polyadenylation-dependent RRNA Catabolic Process Histone MRNA Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: EXOSC10 STAT1 UBE3A	35 interactors: ALDH1B1 B9D1 CHPF CIB1 DIS3 DXO EIF3M EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 FERMT3 FOXRED1 IMMT LCAT LSM2 LSM8 MPHOSPH6 MPP6 NOMO1 NOMO2 PTGES2 RPE RUVBL2 SCRIB SKIV2L SSRP1 TARDBP TOX4 UPF2 USP16 USP21 XRN1 XRN2
Entrez ID		283820	5394
HPRD ID		12375	16180
Ensembl ID		ENSG00000185164	ENSG00000171824
Uniprot IDs		Q4G177 Q5JPE7	Q01780 Q96G78
PDB IDs			2CPR 3SAF 3SAG 3SAH
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Macrophage Fusion Sperm Entry Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Negative Regulation By Virus Of Viral Protein Levels In Host Cell Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Negative Regulation Of Nephron Tubule Epithelial Cell Differentiation Metanephric Mesenchymal Cell Proliferation Involved In Metanephros Development Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Metanephric Mesenchymal Cell Differentiation Urogenital System Development Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Nuclear MRNA Surveillance RNA Surveillance Mesenchymal Cell Differentiation Involved In Kidney Development Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Cell Proliferation Involved In Metanephros Development Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Intracellular MRNA Localization Dosage Compensation RRNA Catabolic Process Cell Differentiation Involved In Metanephros Development Viral Process Cellular Response To Interferon-beta Cell Proliferation Involved In Kidney Development Maturation Of 5.8S RRNA Mesenchymal Cell Proliferation Metanephric Mesenchyme Development Response To Interferon-beta Regulation Of Nephron Tubule Epithelial Cell Differentiation Prostate Gland Growth Histone MRNA Metabolic Process Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Epithelial Cell Differentiation Involved In Kidney Development JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Response To Interferon-gamma Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Cellular Macromolecule Catabolic Process Negative Regulation Of Endothelial Cell Proliferation Negative Regulation Of Epithelial Cell Differentiation Tumor Necrosis Factor-mediated Signaling Pathway Lipopolysaccharide-mediated Signaling Pathway Protein K48-linked Ubiquitination Androgen Receptor Signaling Pathway Cell Differentiation Involved In Kidney Development	Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process MRNA Metabolic Process RRNA Metabolic Process RRNA Processing Aromatic Compound Catabolic Process Cellular Macromolecule Catabolic Process Ribosome Biogenesis Ribonucleoprotein Complex Biogenesis RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Catabolic Process RNA Metabolic Process NcRNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nuclear MRNA Surveillance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Deamination RNA Surveillance Nucleic Acid Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis Gene Expression Maturation Of 5.8S RRNA Histone MRNA Catabolic Process RRNA Catabolic Process Cellular Metabolic Process DNA Modification Protein K63-linked Deubiquitination Histone Deubiquitination Histone MRNA Metabolic Process DNA Metabolic Process Chromatin Modification Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Male Germ Cell Proliferation Metabolic Process Chromatin Remodeling MRNA Processing Regulation Of RNA Stability Chromatin Organization Thrombopoietin-mediated Signaling Pathway Posttranscriptional Regulation Of Gene Expression Histone H2A K63-linked Deubiquitination Regulation Of Male Germ Cell Proliferation Endomitotic Cell Cycle
Tagcloud ?			18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast
Tagcloud (Difference) ?			18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast
Tagcloud (Intersection) ?