PPP2R3B and TMEM14B

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		PPP2R3B	TMEM14B
Description		protein phosphatase 2 regulatory subunit B''beta	transmembrane protein 14B
Image			No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm Cytosol Cilium	Membrane Mitochondrial Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Protein Phosphatase Regulator Activity Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Protein Dephosphorylation Regulation Of Cell Cycle	Heme Biosynthetic Process Nervous System Development Cerebral Cortex Development Neural Precursor Cell Proliferation Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Inhibition of replication initiation of damaged DNA by RB1/E2F1 Cyclin D associated events in G1 Cyclin A/B1/B2 associated events during G2/M transition
Drugs
Diseases
GWAS			Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		11 interacting genes: CDC6 DUSP12 HGS NAA10 NOD2 PPP2CA PPP2R1A PPP2R1B SHANK3 TMEM14B UBC	235 interacting genes: ABHD16A ABHD5 ACSL5 ADAM33 AGPAT3 AGPAT4 AGR3 AGTRAP APOC2 APOC4 ARL13B ARL6IP1 ARL8B ARV1 ATP13A1 B4GALT7 BIK BLCAP BMP10 BSG BTN2A2 C10orf67 C14orf180 C1GALT1 C2CD2L CCL4 CD79A CEPT1 CFHR5 CIDEB CLDN10 CLDND2 CMTM5 CMTM8 CNIH2 CNIH3 CNIH4 COMT CPLX4 CREB3 CREB3L1 CXCL16 CYB561 CYB5R3 DEFB103A DEFB103B DGAT2L6 DHRSX EBP EI24 EMC6 EPHX4 ERGIC3 EXTL1 FA2H FADS6 FAM209A FCER1G FHL3 FIS1 FKBP8 FUNDC2 FXYD6-FXYD2 GDAP1 GIMAP1 GPR152 GPX8 GYPA GYPC HEXB HIBADH HIGD1C HMOX1 HMOX2 HSD17B11 HSD17B13 HSD3B1 IER3IP1 IFITM3 INSIG2 ITGAM JAGN1 KCNA1 KCNK1 KHDRBS2 LEPROTL1 LMNA LPAR3 LRCH1 MAL2 MARCHF5 MEOX2 MFSD12 MGAM MID2 MMD2 MS4A13 MS4A4A NAT8 NCALD NDUFA3 NEU1 NINJ1 NINJ2 NIPAL3 ORMDL1 OTULINL PAGE1 PDPN PDZK1IP1 PEX11G PIGF PLLP PLP1 PLP2 PMP22 PNLIPRP1 PPP2R3B PRAF2 PRH1 PRTFDC1 PSMD3 PTPMT1 RABAC1 REEP4 RHD RHOT2 SAR1B SCAMP5 SCN3B SCRG1 SERF1A SERF1B SERP1 SERP2 SFT2D1 SFT2D2 SFXN1 SFXN2 SFXN3 SLC10A6 SLC16A10 SLC16A13 SLC18A1 SLC19A3 SLC2A6 SLC30A3 SLC30A8 SLC35A4 SLC35E3 SLC35E4 SLC35F1 SLC35F6 SLC35G1 SLC35H1 SLC39A2 SLC39A7 SLC48A1 SLC61A1 SLC7A8 SMAGP SMPD2 SPRY2 SQLE ST6GAL2 STOM STX12 STX3 STX6 STX8 SUCNR1 SYNGR1 SYNJ2BP TAP1 TAS2R19 TBC1D20 TEX44 THBD TIMM22 TIMM23 TIMMDC1 TLCD1 TM4SF4 TMEM11 TMEM120A TMEM120B TMEM121 TMEM147 TMEM14A TMEM14C TMEM187 TMEM19 TMEM203 TMEM220 TMEM222 TMEM229B TMEM243 TMEM254 TMEM255B TMEM267 TMEM42 TMEM50A TMEM50B TMEM51 TMEM60 TMEM69 TMEM97 TMIE TMUB1 TMX2 TOMM6 TSPAN2 TSPO TVP23B UBE2J1 UBE2J2 UBE3A UBIAD1 UBXN8 UNC50 UNC93A VAMP1 VAMP5 VMA12 VRK2 VTI1B YIF1A YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC11 ZDHHC22 ZDHHC24 ZFPL1
Entrez ID		28227	81853
HPRD ID		02276	15523
Ensembl ID		ENSG00000167393	ENSG00000137210
Uniprot IDs		Q9Y5P8	A0A087WU83 C9JCY4 C9JQS0 Q9NUH8
PDB IDs		4I5L 4I5N 4MEW
Enriched GO Terms of Interacting Partners?		Protein Phosphatase Type 2A Complex Meiotic Sister Chromatid Cohesion, Centromeric Protein Serine/threonine Phosphatase Activity Meiotic Sister Chromatid Cohesion Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand INTAC Complex FAR/SIN/STRIPAK Complex Regulation Of Cell Cycle Process RNA Polymerase II Transcription Initiation Surveillance Negative Regulation Of Hippo Signaling Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition T Cell Homeostasis Nuclear RNA Surveillance Homeostasis Of Number Of Cells Cytosol RNA Surveillance Protein Phosphatase Regulator Activity Sister Chromatid Cohesion Regulation Of Hippo Signaling Transcription Elongation By RNA Polymerase II Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Cell Cycle RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity DNA-templated Transcription Elongation RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Meiotic Spindle Elongation Glycine Secretion, Neurotransmission Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Detection Of Muramyl Dipeptide Muramyl Dipeptide Binding Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Lymphocyte Homeostasis Lateral Plasma Membrane Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Leukocyte Homeostasis Regulation Of Meiotic Cell Cycle Process Involved In Oocyte Maturation Organelle Assembly Positive Regulation Of Heme Biosynthetic Process Regulation Of Synaptic Transmission, Glycinergic Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Detection Of Peptidoglycan Guanylate Kinase-associated Protein Clustering Regulation Of Mitotic Cell Cycle Phase Transition Chromosome Organization Protein Tyrosine Phosphatase Activity Spindle Assembly Regulation Of Heme Biosynthetic Process	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Endomembrane System Golgi Apparatus Lipid Biosynthetic Process Membrane Organization Cellular Localization Transmembrane Transport Golgi Membrane Mitochondrial Outer Membrane Transmembrane Transporter Activity Vesicle-mediated Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Establishment Of Protein Localization Serine Import Into Mitochondrion Organic Cation Transport SNARE Complex Structural Constituent Of Myelin Sheath Mitochondrial Membrane SNAP Receptor Activity Organelle Fusion Monoatomic Ion Transmembrane Transporter Activity Steroid Biosynthetic Process Amino Acid Transport Myelination Axon Ensheathment Vesicle Fusion Organic Hydroxy Compound Transport Organelle Membrane Fusion Lipid Homeostasis Heme Metabolic Process Pigment Metabolic Process Cholesterol Biosynthetic Process Golgi Trans Cisterna Import Into The Mitochondrion COPII-coated ER To Golgi Transport Vesicle Lipid Metabolic Process Heme Oxidation Heme Oxygenase (decyclizing) Activity Amino Acid Transmembrane Transport Golgi Medial Cisterna SNARE Binding Zinc Ion Transmembrane Transporter Activity Sterol Biosynthetic Process Serine Transport Porphyrin-containing Compound Metabolic Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Chemical Homeostasis
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