PPP2R3B

Gene Name		protein phosphatase 2, regulatory subunit B, beta
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Gene Ontology Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Protein Phosphatase Type 2A Regulator Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Dephosphorylation Cell Cycle Arrest Regulation Of Catalytic Activity
Pathways		E2F mediated regulation of DNA replication Cyclin D associated events in G1 G1/S Transition G1 Phase Mitotic G1-G1/S phases Inhibition of replication initiation of damaged DNA by RB1/E2F1 Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: CDC6 DUSP12 PPP2CA PPP2R1A PPP2R1B
Entrez ID		28227
HPRD ID		02276
Ensembl ID		ENSG00000167393
Uniprot IDs		Q9Y5P8
PDB IDs		4I5L 4I5N
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Mitotic Nuclear Envelope Reassembly Regulation Of DNA Replication Nuclear Envelope Reassembly Regulation Of Kinase Activity Negative Regulation Of JAK-STAT Cascade Protein Dephosphorylation Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Inactivation Of MAPK Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Phosphorylation Dephosphorylation Regulation Of Phosphorus Metabolic Process Nuclear Envelope Organization Negative Regulation Of MAP Kinase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of JAK-STAT Cascade Ceramide Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Mitotic Cell Cycle Process Nucleus Organization Regulation Of Protein Kinase Activity Mitotic Cell Cycle Negative Regulation Of Protein Serine/threonine Kinase Activity Second-messenger-mediated Signaling Nuclear-transcribed MRNA Catabolic Process Peptidyl-serine Dephosphorylation Negative Regulation Of Cell Growth Negative Regulation Of MAPK Cascade Sphingolipid Metabolic Process MRNA Catabolic Process Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Catalytic Activity RNA Catabolic Process Cellular Response To Fibroblast Growth Factor Stimulus Apoptotic Process Response To Fibroblast Growth Factor Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Programmed Cell Death Regulation Of Peptidyl-tyrosine Phosphorylation Cell Cycle Process Negative Regulation Of Protein Kinase Activity Cell Death Death Membrane Lipid Metabolic Process Regulation Of Protein Phosphorylation Negative Regulation Of Kinase Activity
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