PPP2R3B and DUSP12

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PPP2R3B	DUSP12
Gene Name		protein phosphatase 2, regulatory subunit B, beta	dual specificity phosphatase 12
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm	Nucleus Cytoplasm
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Protein Phosphatase Type 2A Regulator Activity	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Zinc Ion Binding Kinase Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Dephosphorylation Cell Cycle Arrest Regulation Of Catalytic Activity	Cellular Protein Modification Process Protein Dephosphorylation Positive Regulation Of Glucokinase Activity Peptidyl-tyrosine Dephosphorylation
Pathways		E2F mediated regulation of DNA replication Cyclin D associated events in G1 G1/S Transition G1 Phase Mitotic G1-G1/S phases Inhibition of replication initiation of damaged DNA by RB1/E2F1 Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CDC6 DUSP12 PPP2CA PPP2R1A PPP2R1B	12 interactors: APP CALCOCO2 CCNH EIF5 HSPB8 KIAA1377 MBD6 NR1H2 PPP2R3B PTN RABAC1 USO1
Entrez ID		28227	11266
HPRD ID		02276	05323
Ensembl ID		ENSG00000167393	ENSG00000081721
Uniprot IDs		Q9Y5P8	Q9UNI6
PDB IDs		4I5L 4I5N
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Mitotic Nuclear Envelope Reassembly Regulation Of DNA Replication Nuclear Envelope Reassembly Regulation Of Kinase Activity Negative Regulation Of JAK-STAT Cascade Protein Dephosphorylation Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Inactivation Of MAPK Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Phosphorylation Dephosphorylation Regulation Of Phosphorus Metabolic Process Nuclear Envelope Organization Negative Regulation Of MAP Kinase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of JAK-STAT Cascade Ceramide Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Mitotic Cell Cycle Process Nucleus Organization Regulation Of Protein Kinase Activity Mitotic Cell Cycle Negative Regulation Of Protein Serine/threonine Kinase Activity Second-messenger-mediated Signaling Nuclear-transcribed MRNA Catabolic Process Peptidyl-serine Dephosphorylation Negative Regulation Of Cell Growth Negative Regulation Of MAPK Cascade Sphingolipid Metabolic Process MRNA Catabolic Process Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Catalytic Activity RNA Catabolic Process Cellular Response To Fibroblast Growth Factor Stimulus Apoptotic Process Response To Fibroblast Growth Factor Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Programmed Cell Death Regulation Of Peptidyl-tyrosine Phosphorylation Cell Cycle Process Negative Regulation Of Protein Kinase Activity Cell Death Death Membrane Lipid Metabolic Process Regulation Of Protein Phosphorylation Negative Regulation Of Kinase Activity	Mitotic Cell Cycle Positive Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of High-density Lipoprotein Particle Assembly Synaptic Growth At Neuromuscular Junction Golgi Vesicle Docking Collateral Sprouting In Absence Of Injury Regulation Of High-density Lipoprotein Particle Assembly Learning Regulation Of Catalytic Activity Cell Cycle Negative Regulation Of Pinocytosis G1/S Transition Of Mitotic Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Transcription Initiation From RNA Polymerase II Promoter Mitotic Cell Cycle Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Axon Choice Point Recognition Intracellular Receptor Signaling Pathway Negative Regulation Of Cholesterol Storage Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Vesicle Fusion With Golgi Apparatus Positive Regulation Of Digestive System Process DNA-templated Transcription, Initiation Neuron Remodeling
Tagcloud ?			bmp cacna1d ccl2 cd25 cd26 cdkn1a cml cure dpp4 dysregulation eradication exploited il1rap il2ra kcnk5 lscs marcks microarrays mycn oncogenes perp persistence ptprd refined slc4a4 timeless tki transcriptome withdrawal
Tagcloud (Difference) ?			bmp cacna1d ccl2 cd25 cd26 cdkn1a cml cure dpp4 dysregulation eradication exploited il1rap il2ra kcnk5 lscs marcks microarrays mycn oncogenes perp persistence ptprd refined slc4a4 timeless tki transcriptome withdrawal
Tagcloud (Intersection) ?