DUSP12 and EIF5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DUSP12	EIF5
Gene Name		dual specificity phosphatase 12	eukaryotic translation initiation factor 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Zinc Ion Binding Kinase Binding	Translation Initiation Factor Activity GTPase Activity GTP Binding Translation Factor Activity, Nucleic Acid Binding Poly(A) RNA Binding
	Biological Process	Cellular Protein Modification Process Protein Dephosphorylation Positive Regulation Of Glucokinase Activity Peptidyl-tyrosine Dephosphorylation	Translation Translational Initiation Regulation Of Translational Initiation Gene Expression Cellular Protein Metabolic Process
Pathways			Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Translation Eukaryotic Translation Initiation Cap-dependent Translation Initiation
Drugs
Diseases
GWAS			Red blood cell traits ( 23222517)
Protein-Protein Interactions		12 interactors: APP CALCOCO2 CCNH EIF5 HSPB8 KIAA1377 MBD6 NR1H2 PPP2R3B PTN RABAC1 USO1	14 interactors: APP CSNK2A1 CSNK2B DUSP12 EIF1AX EIF1AY EIF2S2 EIF3D EIF3G EIF4G1 EIF4G2 NCBP2 NRGN PUM1
Entrez ID		11266	1983
HPRD ID		05323	03417
Ensembl ID		ENSG00000081721	ENSG00000100664
Uniprot IDs		Q9UNI6	P55010 Q6IBU0
PDB IDs			2E9H 2G2K 2IU1
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Positive Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of High-density Lipoprotein Particle Assembly Synaptic Growth At Neuromuscular Junction Golgi Vesicle Docking Collateral Sprouting In Absence Of Injury Regulation Of High-density Lipoprotein Particle Assembly Learning Regulation Of Catalytic Activity Cell Cycle Negative Regulation Of Pinocytosis G1/S Transition Of Mitotic Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Transcription Initiation From RNA Polymerase II Promoter Mitotic Cell Cycle Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Axon Choice Point Recognition Intracellular Receptor Signaling Pathway Negative Regulation Of Cholesterol Storage Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Vesicle Fusion With Golgi Apparatus Positive Regulation Of Digestive System Process DNA-templated Transcription, Initiation Neuron Remodeling	Translational Initiation Regulation Of Translation Regulation Of Translational Initiation Posttranscriptional Regulation Of Gene Expression Translation Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Protein Metabolic Process Gene Expression MRNA 3'-end Processing Protein Metabolic Process RNA 3'-end Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Formation Of Translation Preinitiation Complex Ribonucleoprotein Complex Assembly Cellular Macromolecular Complex Assembly Biosynthetic Process Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process SnRNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus Synaptic Growth At Neuromuscular Junction Formation Of Cytoplasmic Translation Initiation Complex Axon Guidance Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Processing Collateral Sprouting In Absence Of Injury Cytokine-mediated Signaling Pathway Male Germ Cell Proliferation Regulation Of Metabolic Process Regulation Of Gene Expression Collateral Sprouting Axon Midline Choice Point Recognition Axonogenesis Cellular Component Assembly Nuclear-transcribed MRNA Catabolic Process MRNA Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis MRNA Catabolic Process Axon Choice Point Recognition Axon Development RNA Processing Cellular Response To Cytokine Stimulus Cell Morphogenesis Involved In Neuron Differentiation Cytoplasmic Translational Initiation Positive Regulation Of Glucokinase Activity Positive Regulation Of Activin Receptor Signaling Pathway Chemotaxis Adiponectin-activated Signaling Pathway
Tagcloud ?		bmp cacna1d ccl2 cd25 cd26 cdkn1a cml cure dpp4 dysregulation eradication exploited il1rap il2ra kcnk5 lscs marcks microarrays mycn oncogenes perp persistence ptprd refined slc4a4 timeless tki transcriptome withdrawal	40s 429c cdna cdnas cloning deduced eif3 encodes eukaryotic frame homogeneity identity incorporated initiator laboratories lysates methionyl mr35 multisubunit p42 polyhistidine reading similarity tagged tif35p transiently trna u20s ydr
Tagcloud (Difference) ?		bmp cacna1d ccl2 cd25 cd26 cdkn1a cml cure dpp4 dysregulation eradication exploited il1rap il2ra kcnk5 lscs marcks microarrays mycn oncogenes perp persistence ptprd refined slc4a4 timeless tki transcriptome withdrawal	40s 429c cdna cdnas cloning deduced eif3 encodes eukaryotic frame homogeneity identity incorporated initiator laboratories lysates methionyl mr35 multisubunit p42 polyhistidine reading similarity tagged tif35p transiently trna u20s ydr
Tagcloud (Intersection) ?