DUSP12

Description		dual specificity phosphatase 12
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Zinc Ion Binding Hydrolase Activity Phosphatase Activity Kinase Binding Metal Ion Binding
	Biological Process	Dephosphorylation Protein Modification Process
Pathways
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Immunoglobulin measurement (zinc sulfate turbidity test) ( 29403010) Non-albumin protein levels ( 29403010) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		14 interacting genes: APP CALCOCO2 CCNH CEP126 EIF5 HSPB8 M6PR MBD6 NR1H2 PPP2R3B PTN RABAC1 SRC USO1
Entrez ID		11266
HPRD ID		05323
Ensembl ID		ENSG00000081721
Uniprot IDs		Q9UNI6
PDB IDs		4JNB 4KI9
Enriched GO Terms of Interacting Partners?		Signaling Receptor Activator Activity Negative Regulation Of Long-term Synaptic Potentiation Perinuclear Region Of Cytoplasm Molecular Function Activator Activity Response To Auditory Stimulus Positive Regulation Of Glycolytic Process Integrin Binding Ephrin Receptor Binding Positive Regulation Of Small Molecule Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Catabolic Process Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of ATP Metabolic Process Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation Dendrite Development Oogenesis Positive Regulation Of Secretion Of Lysosomal Enzymes Golgi Vesicle Docking Acetylcholine Receptor Activator Activity Positive Regulation Of Cellular Component Organization PTB Domain Binding Response To Interleukin-1 Regulation Of ATP Metabolic Process Collateral Sprouting In Absence Of Injury Myeloid Cell Development Regulation Of Protein Import Regulation Of Carbohydrate Catabolic Process Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Small Molecule Metabolic Process Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Endocytosis Transcription Factor TFIIK Complex Cadherin Binding Eukaryotic Initiation Factor EIF2 Binding Female Gamete Generation Dendrite Regeneration Ossification Involved In Bone Remodeling
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