GPI and AMFR

Number of citations of the paper that reports this interaction (PMID 16563432)
2

Data Source:
HPRD (in vitro)

		GPI	AMFR
Gene Name		glucose-6-phosphate isomerase	autocrine motility factor receptor, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Neuron Projection Extracellular Vesicular Exosome	Hrd1p Ubiquitin Ligase Complex Nucleus Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Dendrite Growth Cone Neuronal Cell Body Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Glucose-6-phosphate Isomerase Activity Cytokine Activity Growth Factor Activity Intramolecular Transferase Activity Monosaccharide Binding	Ubiquitin-protein Transferase Activity Receptor Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Activity
	Biological Process	Angiogenesis Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Humoral Immune Response Hemostasis Learning Or Memory Pathogenesis Methylglyoxal Biosynthetic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Small Molecule Metabolic Process Aldehyde Catabolic Process Glucose 6-phosphate Metabolic Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Movement Of Cell Or Subcellular Component Signal Transduction Aging Learning Or Memory ER-associated Ubiquitin-dependent Protein Catabolic Process Endoplasmic Reticulum Unfolded Protein Response Protein Oligomerization
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs		Alpha-D-Glucose-6-Phosphate 6-Phosphogluconic Acid 5-Phospho-D-Arabinohydroxamic Acid Sorbitol 6-phosphate 5-Phosphoarabinonic Acid Glucose-6-Phosphate Erythose-4-Phosphate Fructose-6-Phosphate
Diseases
GWAS
Protein-Protein Interactions		5 interactors: AMFR CSNK2A1 IGFBP3 PARP14 PCNA	26 interactors: BAG6 CRMP1 CYP2E1 CYP3A4 DERL1 DHFR GPI HERPUD1 HTT KPNB1 SOD1 SYVN1 TOM1L1 TRIM25 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2G1 UBE2G2 UBE2K UBE2N UBE2T UBE2W UFD1L VCP
Entrez ID		2821	267
HPRD ID		01394	09130
Ensembl ID		ENSG00000105220	ENSG00000159461
Uniprot IDs		P06744	Q9UKV5
PDB IDs		1IAT 1IRI 1JIQ 1JLH 1NUH	2EJS 2LVN 2LVO 2LVP 2LVQ 2LXH 2LXP 3FSH 3H8K 3TIW 4G3O
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Deoxyribonuclease Activity Leading Strand Elongation	Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Catabolic Process Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis Proteasomal Protein Catabolic Process Cellular Metabolic Process Cellular Response To Stress Protein K11-linked Ubiquitination Cellular Protein Metabolic Process Response To Endoplasmic Reticulum Stress Response To Stress Protein K63-linked Ubiquitination Response To Organic Substance ER-associated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Topologically Incorrect Protein Cellular Response To Organic Substance Response To Stimulus Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Metabolic Process Protein Metabolic Process Cellular Protein Modification Process Toll-like Receptor 4 Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Apoptotic Process Toll-like Receptor Signaling Pathway Programmed Cell Death Cell Death Death Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Retrograde Protein Transport, ER To Cytosol Response To Unfolded Protein Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Protein Monoubiquitination Monoterpenoid Metabolic Process
Tagcloud ?		3h anchor anchored autoantibodies biosynthetic clone cytofluorimetry ecd ethanolamine existence full glycosylphosphatidylinositol immunoblotting inside internally mr pass phospholipase polypeptide radioligand retains sera smallest solely tail thyrotrophin transmembrane tsh tshr	anchoring catalyzed dnas e3 eris facilitating herpes hsv insig1 interacted k27 ligase microbial microsomes missing mita mpys perinuclear platform polyubiquitination recruiting revealing served simplex stimulator sting tank tbk1 uncovers
Tagcloud (Difference) ?		3h anchor anchored autoantibodies biosynthetic clone cytofluorimetry ecd ethanolamine existence full glycosylphosphatidylinositol immunoblotting inside internally mr pass phospholipase polypeptide radioligand retains sera smallest solely tail thyrotrophin transmembrane tsh tshr	anchoring catalyzed dnas e3 eris facilitating herpes hsv insig1 interacted k27 ligase microbial microsomes missing mita mpys perinuclear platform polyubiquitination recruiting revealing served simplex stimulator sting tank tbk1 uncovers
Tagcloud (Intersection) ?