GLE1 and UXT

Number of citations of the paper that reports this interaction (PMID 14645504)
18

Data Source:
BioGRID (two hybrid)

		GLE1	UXT
Gene Name		GLE1 RNA export mediator	ubiquitously-expressed, prefoldin-like chaperone
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nuclear Pore Cytoplasm Plasma Membrane Membrane	Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Cytoskeleton
	Molecular Function	Protein Binding Identical Protein Binding	RNA Polymerase II Transcription Corepressor Activity Chromatin Binding Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding
	Biological Process	MRNA Export From Nucleus Protein Transport Poly(A)+ MRNA Export From Nucleus	Negative Regulation Of Transcription From RNA Polymerase II Promoter Microtubule Cytoskeleton Organization Transcription, DNA-templated Mitochondrion Transport Along Microtubule Centrosome Organization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: KRT10 NUP155 NUPL2 UXT	19 interactors: APP AR CECR2 GLE1 KRT31 KRT40 KRTAP10-7 KRTAP10-8 LRPPRC LSM1 NOTCH2NL PAK7 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 VHL
Entrez ID		2733	8409
HPRD ID		04536	02209
Ensembl ID		ENSG00000119392	ENSG00000126756
Uniprot IDs		B3KMG0 Q53GS7	Q9UBK9
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Nuclear Envelope Organization Glucose Transport Hexose Transport Viral Transcription Regulation Of Glucose Transport Nuclear Export MRNA Transport Nucleus Organization Carbohydrate Transport RNA Transport RNA Localization Viral Life Cycle Pathogenesis Nucleocytoplasmic Transport Nuclear Transport Intracellular Transport Atrial Cardiac Muscle Cell To AV Node Cell Communication Atrial Cardiac Muscle Cell Action Potential Endomembrane System Organization Cytokine-mediated Signaling Pathway Establishment Of Localization In Cell Mitochondrion Transport Along Microtubule Cell-cell Signaling Involved In Cardiac Conduction Establishment Of Mitochondrion Localization Viral Process Cellular Response To Cytokine Stimulus RNA Biosynthetic Process Cellular Localization Cardiac Muscle Cell Action Potential Involved In Contraction Mitotic Cell Cycle Process Cytoplasmic Transport Response To Cytokine Mitotic Cell Cycle Mitochondrion Localization Cardiac Muscle Cell Action Potential Protein Export From Nucleus Membrane Organization Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Cellular Response To Calcium Ion Intracellular Protein Transport Organelle Organization RNA Metabolic Process Organelle Transport Along Microtubule Carbohydrate Metabolic Process Cell Cycle Process Gene Expression MRNA Export From Nucleus	Cell Growth Single-organism Behavior Posttranscriptional Regulation Of Gene Expression Locomotory Behavior Behavior Neuron Apoptotic Process Learning Or Memory Negative Regulation Of Integrin Biosynthetic Process Developmental Process Neuron Death Cognition Synaptic Growth At Neuromuscular Junction Positive Regulation Of Progesterone Secretion Negative Regulation Of Mitochondrial RNA Catabolic Process Anatomical Structure Development Collateral Sprouting In Absence Of Injury Positive Regulation Of Integrin Biosynthetic Process Regulation Of Progesterone Secretion Cellular Macromolecule Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Hair Follicle Cell Proliferation Regulation Of Integrin Biosynthetic Process MRNA Transport Neuron Development Memory Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Steroid Hormone Microtubule-based Transport Programmed Cell Death Regulation Of Protein Stability Skeletal Muscle Tissue Development RNA Transport Learning Notch Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Skeletal Muscle Atrophy Growth Cytoskeleton-dependent Intracellular Transport Tissue Development Cell Death Death Skeletal Muscle Organ Development RNA Localization Axon Choice Point Recognition Striated Muscle Atrophy Response To Abiotic Stimulus
Tagcloud ?		als amyotrophic arthrogryposis autosomal carries causative congenital contracture deleterious export fatal fus global haploinsufficiency hela hgle1 horn lethal missense morphants motor neuron nonsense pore recessive rescue splice unable zebrafish	angiogenesis attenuates consequent csl developmentally division endogenously evolutionarily impairing indispensable inductions intersegmental isv isvs jkappa mechanistically myriad nicd notch orchestrated rbp repressor rescues shedding spatially temporally tip vessel zebrafish
Tagcloud (Difference) ?		als amyotrophic arthrogryposis autosomal carries causative congenital contracture deleterious export fatal fus global haploinsufficiency hela hgle1 horn lethal missense morphants motor neuron nonsense pore recessive rescue splice unable	angiogenesis attenuates consequent csl developmentally division endogenously evolutionarily impairing indispensable inductions intersegmental isv isvs jkappa mechanistically myriad nicd notch orchestrated rbp repressor rescues shedding spatially temporally tip vessel
Tagcloud (Intersection) ?		zebrafish