GLE1 and NUP155

Number of citations of the paper that reports this interaction (PubMedID 14645504)
0

Data Source:
HPRD (two hybrid, in vitro)

		GLE1	NUP155
Description		GLE1 RNA export mediator	nucleoporin 155
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GO Annotations	Cellular Component	Extracellular Space Nucleus Nuclear Envelope Nuclear Pore Nucleolus Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Ciliary Basal Body Nuclear Pore Cytoplasmic Filaments	Nucleus Nuclear Envelope Nuclear Pore Cytosol Membrane Nuclear Membrane Nuclear Pore Inner Ring
	Molecular Function	Inositol Hexakisphosphate Binding Protein Binding Phospholipid Binding Translation Initiation Factor Binding Identical Protein Binding	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	MRNA Export From Nucleus Nucleocytoplasmic Transport Protein Transport Poly(A)+ MRNA Export From Nucleus MRNA Transport	Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery RNA Export From Nucleus MRNA Export From Nucleus Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Envelope Organization Protein Transport Protein Localization To Nucleus MiRNA Processing Protein Localization To Nuclear Inner Membrane MRNA Transport Atrial Cardiac Muscle Cell Action Potential
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript	ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases		Lethal arthrogryposis with anterior horn cell disease Lethal congenital contractural syndrome (LCCS)
GWAS		Axial length ( 24144296) Body mass index ( 26426971)	Malaria ( 31844061) Meat-related diet ( 32066663)
Interacting Genes		4 interacting genes: KRT10 NUP155 NUP42 UXT	7 interacting genes: CDC42 EFS GLE1 NUP35 PDCD6IP UBC ZFYVE9
Entrez ID		2733	9631
HPRD ID		04536	05984
Ensembl ID		ENSG00000119392	ENSG00000113569
Uniprot IDs		A0A804HJ70 B3KMG0 Q53GS7	B4DLT2 E9PF10 O75694
PDB IDs		6B4F 6B4I 6B4J	5A9Q 5IJN 5IJO 7EYE 7EYF 7EYQ 7PER 7R1Y 7R5J 7R5K
Enriched GO Terms of Interacting Partners?		Intracellular Transport Cellular Localization Establishment Of Localization In Cell Nuclear Envelope Nuclear Membrane Centrosome Cycle Microtubule Organizing Center Organization Organelle Transport Along Microtubule Nuclear Pore Protein Tetramerization Cytoskeleton Nuclear Pore Inner Ring Protein Localization To Nuclear Inner Membrane RNA Transport MRNA Transport Nuclear Export Nuclear Migration Along Microfilament Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Spindle Pole Positive Regulation Of Protein Glycosylation Transport Along Microtubule Nuclear Migration Along Microtubule Cytoskeleton-nuclear Membrane Anchor Activity Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Golgi Disassembly Nucleobase-containing Compound Transport Regulation Of Protein Glycosylation Microtubule-based Transport Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Cytoskeleton Organization Golgi Ribbon Formation Microtubule Binding Protein Complex Oligomerization Importin-alpha Family Protein Binding Establishment Of Organelle Localization Nuclear Transport Nucleocytoplasmic Transport Atrial Cardiac Muscle Cell Action Potential Meiotic Nuclear Membrane Microtubule Tethering Complex Golgi Cis Cisterna RPAP3/R2TP/prefoldin-like Complex Nuclear Export Signal Receptor Activity Protein Transport Asymmetric Cell Division Protein Localization To Nuclear Envelope Meiotic Spindle Assembly Protein Heterotetramerization Organelle Organization Positive Regulation Of Glycoprotein Biosynthetic Process	Apolipoprotein A-I Receptor Binding Cellular Localization Endothelin Receptor Signaling Pathway Involved In Heart Process Focal Adhesion Establishment Or Maintenance Of Apical/basal Cell Polarity Centrosome Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Neuropilin Signaling Pathway GBD Domain Binding Storage Vacuole Establishment Of Localization In Cell Intracellular Transport Establishment Or Maintenance Of Cell Polarity RNA Transport Inositol Hexakisphosphate Binding Nuclear Pore Cytoplasmic Filaments Phospholipid Binding MRNA Transport Nuclear Pore Extracellular Vesicle Biogenesis Extracellular Exosome Biogenesis Nucleus Organization Positive Regulation Of Extracellular Exosome Assembly Proteinase Activated Receptor Binding Actomyosin Contractile Ring Assembly Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell-cell Junction Organization Positive Regulation Of Pinocytosis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Extracellular Exosome Assembly Nuclear Pore Central Transport Channel Intracellular Protein Localization Nucleobase-containing Compound Transport Nuclear Envelope Establishment Of Golgi Localization Protein Domain Specific Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Leading Edge Membrane Thioesterase Binding Neuron Fate Determination Golgi Transport Complex Actomyosin Nuclear Transport Nucleocytoplasmic Transport Endothelin Receptor Signaling Pathway Cell Junction Assembly Cytosol
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