GLE1 and KRT10

Number of citations of the paper that reports this interaction (PMID 14645504)
18

Data Source:
BioGRID (two hybrid)

		GLE1	KRT10
Gene Name		GLE1 RNA export mediator	keratin 10, type I
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nuclear Pore Cytoplasm Plasma Membrane Membrane	Extracellular Space Nucleus Cytoplasm Intermediate Filament Membrane Keratin Filament Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Structural Constituent Of Epidermis
	Biological Process	MRNA Export From Nucleus Protein Transport Poly(A)+ MRNA Export From Nucleus	Keratinocyte Differentiation Cellular Response To Calcium Ion
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: KRT10 NUP155 NUPL2 UXT	5 interactors: AKT1 EVPL GLE1 PRKCZ SMAD3
Entrez ID		2733	3858
HPRD ID		04536	01021
Ensembl ID		ENSG00000119392	ENSG00000186395
Uniprot IDs		B3KMG0 Q53GS7	P13645
PDB IDs			3ASW 4F1Z
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Nuclear Envelope Organization Glucose Transport Hexose Transport Viral Transcription Regulation Of Glucose Transport Nuclear Export MRNA Transport Nucleus Organization Carbohydrate Transport RNA Transport RNA Localization Viral Life Cycle Pathogenesis Nucleocytoplasmic Transport Nuclear Transport Intracellular Transport Atrial Cardiac Muscle Cell To AV Node Cell Communication Atrial Cardiac Muscle Cell Action Potential Endomembrane System Organization Cytokine-mediated Signaling Pathway Establishment Of Localization In Cell Mitochondrion Transport Along Microtubule Cell-cell Signaling Involved In Cardiac Conduction Establishment Of Mitochondrion Localization Viral Process Cellular Response To Cytokine Stimulus RNA Biosynthetic Process Cellular Localization Cardiac Muscle Cell Action Potential Involved In Contraction Mitotic Cell Cycle Process Cytoplasmic Transport Response To Cytokine Mitotic Cell Cycle Mitochondrion Localization Cardiac Muscle Cell Action Potential Protein Export From Nucleus Membrane Organization Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Cellular Response To Calcium Ion Intracellular Protein Transport Organelle Organization RNA Metabolic Process Organelle Transport Along Microtubule Carbohydrate Metabolic Process Cell Cycle Process Gene Expression MRNA Export From Nucleus	Positive Regulation Of Glucose Import Negative Regulation Of Protein Phosphorylation Positive Regulation Of Glucose Transport Positive Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell Adhesion Negative Regulation Of Phosphorylation Regulation Of Glucose Import Epithelial Cell Differentiation Cellular Response To Growth Factor Stimulus Regulation Of Glucose Transport Response To Growth Factor Wound Healing Regulation Of Cell Adhesion Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Peptidyl-serine Phosphorylation Positive Regulation Of Transforming Growth Factor Beta3 Production Glycogen Cell Differentiation Involved In Embryonic Placenta Development Regulation Of Establishment Of Protein Localization Cell Activation Response To Wounding Positive Regulation Of Transport Osteoblast Differentiation Regulation Of Protein Localization Transforming Growth Factor Beta Receptor Signaling Pathway Insulin Receptor Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Positive Regulation Of Cell Differentiation Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cell-substrate Adhesion Positive Regulation Of T-helper 2 Cell Cytokine Production Positive Regulation Of Interleukin-10 Secretion Evasion Or Tolerance Of Host Defenses By Virus Response To Transforming Growth Factor Beta Negative Regulation Of Cell Death Platelet Activation Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of T Cell Activation Cellular Response To Insulin Stimulus Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cysteine-type Endopeptidase Activity
Tagcloud ?		als amyotrophic arthrogryposis autosomal carries causative congenital contracture deleterious export fatal fus global haploinsufficiency hela hgle1 horn lethal missense morphants motor neuron nonsense pore recessive rescue splice unable zebrafish	ceph d17s181 d17s183 d17s190 d17s250 d17s507 d17s508 d17s509 d17s518 d17s579 d17s78 d17s791 d17s797 d17s80 d17s800 d17s806 d17s810 d17s855 d17s856 d17s857 d17s858 d17s859 edh17b epb3 gp3a hox2b kindreds ppy thra1
Tagcloud (Difference) ?		als amyotrophic arthrogryposis autosomal carries causative congenital contracture deleterious export fatal fus global haploinsufficiency hela hgle1 horn lethal missense morphants motor neuron nonsense pore recessive rescue splice unable zebrafish	ceph d17s181 d17s183 d17s190 d17s250 d17s507 d17s508 d17s509 d17s518 d17s579 d17s78 d17s791 d17s797 d17s80 d17s800 d17s806 d17s810 d17s855 d17s856 d17s857 d17s858 d17s859 edh17b epb3 gp3a hox2b kindreds ppy thra1
Tagcloud (Intersection) ?