PLXNB2 and HMOX2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		PLXNB2	HMOX2
Description		plexin B2	heme oxygenase 2
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GO Annotations	Cellular Component	Semaphorin Receptor Complex Plasma Membrane Cell Surface Membrane Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Semaphorin Receptor Activity Signaling Receptor Activity	Heme Oxygenase (decyclizing) Activity Protein Binding Oxidoreductase Activity Heme Binding Metal Ion Binding
	Biological Process	Neural Tube Closure Regulation Of Protein Phosphorylation Cytoplasmic Translation Receptor-mediated Endocytosis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Neuroblast Proliferation Synapse Assembly Brain Development Regulation Of Cell Shape Regulation Of Neuron Projection Development Positive Regulation Of Neuron Projection Development Regulation Of Cell Migration Positive Regulation Of Cell Projection Organization Negative Regulation Of Translation In Response To Stress Cellular Response To Stress TRNA Stabilization Regulation Of GTPase Activity Positive Regulation Of Translation Positive Regulation Of Axonogenesis Regulation Of Protein Metabolic Process Semaphorin-plexin Signaling Pathway Excitatory Synapse Assembly Regulation Of Neuron Migration	Response To Hypoxia Heme Oxidation Response To Oxidative Stress Heme Catabolic Process
Pathways			Heme degradation Neutrophil degranulation RHOA GTPase cycle Iron uptake and transport Cytoprotection by HMOX1
Drugs			NADH Stannsoporfin
Diseases
GWAS		Acne (severe) ( 24927181) Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576) Cutaneous malignant melanoma ( 32341527) Cutaneous melanoma or hair colour ( 32341527) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte count ( 32888494) Nevus count or cutaneous melanoma ( 32341527) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sensorimotor dexterity ( 31596458) Systolic blood pressure ( 30224653)	Erectile dysfunction ( 30583798)
Interacting Genes		9 interacting genes: AIFM2 ARHGEF11 ARHGEF12 CENPU HDLBP HMOX2 PFDN1 PTN RND1	67 interacting genes: A2M APP AQP6 ARL13B ASGR2 ATP5F1B BCL2L13 BIK BLOC1S2 CCR2 CD79A CEBPZ CEP126 COPS6 CRB3 CSNK2A1 EBP EEF1G EIF3C ELOVL4 ERGIC3 F2RL1 FAM209A FAM210B GET1 GIT1 GPR152 GPRASP1 GPX8 HAP1 IMMT INPP5K ITFG1 JADE1 KCNJ6 KCNMA1 LAPTM5 LRIF1 MED31 MGST3 MTNR1A NDUFS2 NKRF NR3C1 PCNT PLXNB2 PTGER4 RBBP4 RETREG3 RNASEK SAR1A SETDB1 SGPL1 SHC1 SKA2 SLC30A8 SMO SNX5 SNX7 SSMEM1 STOM SYT1 TMEM14B TMX2 VMA21 ZFP28 ZNF746
Entrez ID		23654	3163
HPRD ID		05050	00783
Ensembl ID		ENSG00000196576	ENSG00000103415
Uniprot IDs		O15031	A0A087WT44 B3KSE0 P30519
PDB IDs		4E71	2Q32 2QPP 2RGZ 4WMH 5UC8 5UC9 5UCA
Enriched GO Terms of Interacting Partners?			Membrane Protein Binding
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