TCL1A and HIST3H2A

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TCL1A	HIST3H2A
Gene Name		T-cell leukemia/lymphoma 1A	histone cluster 3, H2a
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Cell Cortex Pronucleus	Nuclear Nucleosome Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	DNA Binding Protein Heterodimerization Activity
	Biological Process	Multicellular Organismal Development Stem Cell Maintenance	Nucleosome Disassembly UV-damage Excision Repair
Pathways			Chromatin modifying enzymes HDACs deacetylate histones Chromatin organization HATs acetylate histones RMTs methylate histone arginines
Drugs
Diseases
GWAS		Adverse response to aromatase inhibitors ( 21172079 20876420)
Protein-Protein Interactions		21 interactors: AKT1 AKT2 AKT3 ALS2CR12 ATM CADPS CALCOCO2 CARD9 CEP55 DNMT3A GOLGA2 HIST3H2A LSM3 PRTFDC1 TCF4 TP53BP2 TRAF1 TTC33 TXLNA TXLNB WDR47	5 interactors: CBX5 DNTTIP2 KRTAP10-3 RPS6KA5 TCL1A
Entrez ID		8115	92815
HPRD ID		01744	13660
Ensembl ID		ENSG00000100721	ENSG00000181218
Uniprot IDs		P56279	Q7L7L0
PDB IDs		1JSG
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Glucose Metabolic Process Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Glycogen Metabolic Process Polysaccharide Metabolic Process Peripheral Nervous System Myelin Maintenance Positive Regulation Of Glycogen Biosynthetic Process Glial Cell Development Regulation Of Glucose Metabolic Process Regulation Of Fatty Acid Beta-oxidation Myelin Maintenance Mammary Gland Epithelial Cell Differentiation Energy Reserve Metabolic Process Negative Regulation Of Lipid Transport Glucose Metabolic Process Glycogen Biosynthetic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Response To Radiation Glial Cell Differentiation Regulation Of Fatty Acid Transport Cell Cycle Myelination In Peripheral Nervous System Positive Regulation Of Glucose Import Intrinsic Apoptotic Signaling Pathway Cellular Polysaccharide Biosynthetic Process Regulation Of Glycogen Metabolic Process Schwann Cell Development Positive Regulation Of Glucose Transport Regulation Of Extrinsic Apoptotic Signaling Pathway Polysaccharide Biosynthetic Process Regulation Of Cell Cycle Hexose Metabolic Process Apoptotic Process Negative Regulation Of Ion Transmembrane Transport Positive Regulation Of Intracellular Transport Cellular Carbohydrate Metabolic Process Regulation Of Myelination Gliogenesis Programmed Cell Death Schwann Cell Differentiation Monosaccharide Metabolic Process Negative Regulation Of Transmembrane Transport Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Glycogen Cell Differentiation Involved In Embryonic Placenta Development Cell Death Regulation Of Glucose Import Death Regulation Of Lipid Catabolic Process Positive Regulation Of Lipid Biosynthetic Process	Histone H2A-S1 Phosphorylation Histone H3-S10 Phosphorylation Positive Regulation Of Histone Phosphorylation Histone H3-S28 Phosphorylation
Tagcloud ?		14q atm coexpression cutaneous cutis epidermotropism gains immunophenotype infiltrates institution integral inversion involvement irregular karyotype lactate lymphoid manifestations papules periadnexal perivascular pll plls prolymphocytic purpura rash rearrangement sized ulcers
Tagcloud (Difference) ?		14q atm coexpression cutaneous cutis epidermotropism gains immunophenotype infiltrates institution integral inversion involvement irregular karyotype lactate lymphoid manifestations papules periadnexal perivascular pll plls prolymphocytic purpura rash rearrangement sized ulcers
Tagcloud (Intersection) ?