NARS1

Name	asparaginyl-tRNA synthetase 1
Structure
Novel Interactors	1 novel interactors: DCC
Interactors	6 interactors: ATXN1 CEBPA DSCR9 HSPB2 LSM1 SUMO2
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Nucleotide Binding Nucleic Acid Binding Aminoacyl-tRNA Ligase Activity Asparagine-tRNA Ligase Activity Protein Binding ATP Binding Ligase Activity CCR3 Chemokine Receptor Binding Protein Dimerization Activity
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Asparaginyl-tRNA Aminoacylation Cell Migration Cerebral Cortex Development
Pathways	Cytosolic tRNA aminoacylation
Drugs	Asparagine
GWAS	No GWAS studies recorded
Entrez ID	4677
HPRD ID	00154
Ensembl ID	ENSG00000134440
Uniprot IDs	O43776
PDB IDs	4ZYA 5XIX 8H53 8TC7 8TC8 8TC9
GO Terms Enriched among Interactors ?	Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process CHOP-C/EBP Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Nuclear Matrix Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Response To Vitamin B2 White Fat Cell Proliferation Memory C/EBP Complex Regulation Of Cell Differentiation Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Dorsal/ventral Axon Guidance Spinal Cord Ventral Commissure Morphogenesis Somatic Muscle Development POZ Domain Binding Lsm1-7-Pat1 Complex Positive Regulation Of Proteolysis Response To Phenylpropanoid Regulation Of Proteasomal Protein Catabolic Process Anterior/posterior Axon Guidance Negative Regulation Of Dendrite Development Positive Regulation Of Protein Catabolic Process Fat Cell Proliferation Poly(G) Binding Regulation Of Cell Development Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Postsynapse