FOXP1 and FOXP4

Number of citations of the paper that reports this interaction (PMID 14701752)
56

Data Source:
HPRD (two hybrid, in vitro)

		FOXP1	FOXP4
Gene Name		forkhead box P1	forkhead box P4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Androgen Receptor Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of B Cell Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Endothelial Cell Migration Osteoclast Differentiation Response To Lipopolysaccharide Regulation Of Tumor Necrosis Factor Production Chemokine (C-C Motif) Ligand 2 Secretion Osteoclast Development Macrophage Activation Monocyte Activation Endothelial Cell Activation Regulation Of Monocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Interleukin-1 Beta Secretion Regulation Of Inflammatory Response Negative Regulation Of Androgen Receptor Signaling Pathway T Follicular Helper Cell Differentiation Interleukin-21 Secretion Regulation Of Defense Response To Bacterium Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Endothelial Tube Morphogenesis Regulation Of Interleukin-12 Secretion	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Heart Development Embryonic Foregut Morphogenesis Lung Secretory Cell Differentiation Negative Regulation Of Lung Goblet Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18821565) Subcutaneous adipose tissue ( 22589738)	Prostate cancer ( 20676098)
Protein-Protein Interactions		5 interactors: CTBP1 FOXP2 FOXP4 IL3RA NCOR2	2 interactors: FOXP1 FOXP2
Entrez ID		27086	116113
HPRD ID		18518	10600
Ensembl ID		ENSG00000114861	ENSG00000137166
Uniprot IDs		E9PFD3 Q548T7 Q8N2P0 Q8TEA2 Q9H334	Q8IVH2
PDB IDs		2KIU
Enriched GO Terms of Interacting Partners?		White Fat Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Lung Development Respiratory Tube Development Respiratory System Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Lung Epithelial Cell Differentiation Lung Cell Differentiation Lung Epithelium Development Regulation Of Transcription From RNA Polymerase II Promoter Putamen Development Caudate Nucleus Development Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Tube Development Fat Cell Differentiation Negative Regulation Of Cellular Metabolic Process Interleukin-3-mediated Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Lung Goblet Cell Differentiation Vocal Learning Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Cellular Response To Interleukin-3 Righting Reflex Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Telencephalon Development RNA Metabolic Process Negative Regulation Of Histone H4 Acetylation Gene Expression Auditory Behavior Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Lung Secretory Cell Differentiation Striatum Development Forebrain Development Tissue Development Regulation Of Histone H4 Acetylation Mechanosensory Behavior Type I Pneumocyte Differentiation Response To Auditory Stimulus Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Histone Deacetylation Negative Regulation Of Histone Acetylation Heart Development	Smooth Muscle Tissue Development Positive Regulation Of Mesenchymal Cell Proliferation Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Stem Cell Proliferation Regulation Of Stem Cell Proliferation Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Positive Regulation Of Epithelial Cell Proliferation Interleukin-21 Secretion Putamen Development Caudate Nucleus Development Lung Development Respiratory Tube Development Muscle Organ Development Respiratory System Development Regulation Of Epithelial Cell Proliferation Regulation Of Endothelial Tube Morphogenesis Negative Regulation Of Lung Goblet Cell Differentiation Chemokine (C-C Motif) Ligand 2 Secretion Striated Muscle Tissue Development Muscle Tissue Development Chemokine Secretion Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Interleukin-12 Secretion T Follicular Helper Cell Differentiation Vocal Learning Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Muscle Structure Development Righting Reflex Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Monocyte Activation Immunoglobulin V(D)J Recombination Osteoclast Development Chemokine Production Auditory Behavior Regulation Of Defense Response To Bacterium Pre-B Cell Differentiation Negative Regulation Of B Cell Apoptotic Process Tube Development Endothelial Cell Activation Immature B Cell Differentiation Lung Secretory Cell Differentiation Negative Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Monocyte Differentiation Positive Regulation Of Cell Proliferation Striatum Development Transcription From RNA Polymerase II Promoter Mechanosensory Behavior Positive Regulation Of Cardiac Muscle Cell Differentiation
Tagcloud ?		3p amplifications breeding classic consuming cooperates costly daunting drive drivers driving endogenously engineering faithful hidden incurable pc pten ptenloxp rapidcap recreate reside rybp sensitized shq1 trp53 trp53loxp unmet validation	ahcy arrays bac balanced breakpoints breaks ctcf dismissed ep300 fusions hcc1187 hcc1806 hybridized idea mapped microarrays oligonucleotide painting participating path pkd1l1 plausible reciprocal rif1 tax1bp1 tiling translocations unbalanced zr
Tagcloud (Difference) ?		3p amplifications breeding classic consuming cooperates costly daunting drive drivers driving endogenously engineering faithful hidden incurable pc pten ptenloxp rapidcap recreate reside rybp sensitized shq1 trp53 trp53loxp unmet validation	ahcy arrays bac balanced breakpoints breaks ctcf dismissed ep300 fusions hcc1187 hcc1806 hybridized idea mapped microarrays oligonucleotide painting participating path pkd1l1 plausible reciprocal rif1 tax1bp1 tiling translocations unbalanced zr
Tagcloud (Intersection) ?