FOXP4 and NR2F2

Number of citations of the paper that reports this interaction (PubMedID 29365100)
0

Data Source:
BioGRID (fluorescent resonance energy transfer)

		FOXP4	NR2F2
Description		forkhead box P4	nuclear receptor subfamily 2 group F member 2
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol	Nucleus Nucleoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Retinoic Acid Binding DNA Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Neuron Migration Maternal Placenta Development Negative Regulation Of Endothelial Cell Proliferation Lymph Vessel Development Positive Regulation Of Systemic Arterial Blood Pressure Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Skeletal Muscle Tissue Development Female Gonad Development Fertilization Anterior/posterior Pattern Specification Radial Pattern Formation Negative Regulation Of Endothelial Cell Migration Cell Differentiation Intracellular Receptor Signaling Pathway Forebrain Development Response To Estradiol Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Blood Vessel Morphogenesis Placenta Blood Vessel Development Trophoblast Giant Cell Differentiation Lymphatic Endothelial Cell Fate Commitment Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Interneuron Migration
Pathways			Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Chronotype ( 30696823) EGFR mutation-positive lung adenocarcinoma ( 27501781) Fasting insulin ( 34059833) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Metabolite levels ( 23823483) Non-small cell lung cancer ( 31326317) Prostate cancer ( 20676098 31562322)	Adventurousness ( 30643258) Birth weight ( 31043758) Cannabis use ( 27023175) Cerebrospinal fluid p-tau levels in Alzheimer's disease dementia ( 29274321) Chronotype ( 30696823) Cognitive decline rate in late mild cognitive impairment ( 26252872) Immune response to measles-mumps-rubella vaccine ( 24811271) Lymphangioleiomyomatosis (sporadic) ( 31000673) Metabolite levels ( 23823483) Motion sickness ( 25628336) Optic disc area ( 25631615) Optic disc size ( 31809533) Photic sneeze reflex ( 27182965) PR interval ( 32439900) Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225) Serum alkaline phosphatase levels ( 33547301) Sex hormone-binding globulin levels ( 22829776) Very long-chain saturated fatty acid levels (fatty acid 22:0) ( 25378659)
Interacting Genes		10 interacting genes: FOXP1 FOXP2 NR2F1 NR2F2 SATB1 SATB2 SOX5 XAGE2 YY1 ZMYM2	21 interacting genes: BCL11A BCL11B BIK EP300 FOXP1 FOXP2 FOXP4 HDAC1 HIPK3 MYOD1 NCOR2 NR2F6 NR3C1 NSD1 PHB2 PIAS1 SETD7 SQSTM1 TENT5A TRIM24 TRIP4
Entrez ID		116113	7026
HPRD ID		10600	00139
Ensembl ID		ENSG00000137166	ENSG00000185551
Uniprot IDs		B7ZBM3 Q8IVH2	F1D8R0 P24468
PDB IDs		6XAT	3CJW
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Activity Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Negative Regulation Of Metabolic Process Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Nuclear Matrix Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of Cardiac Muscle Tissue Growth Negative Regulation Of Organ Growth Nuclear Lumen Negative Regulation Of Cardiac Muscle Hypertrophy Regulation Of Macromolecule Metabolic Process Negative Regulation Of Muscle Hypertrophy Negative Regulation Of Striated Muscle Cell Differentiation Cellular Developmental Process Zinc Ion Binding Nuclear Receptor Activity Regulation Of Metabolic Process Radial Pattern Formation Putamen Development Caudate Nucleus Development Animal Organ Development Skeletal Muscle Tissue Development Regulation Of Heart Growth Negative Regulation Of Muscle Cell Differentiation Regulation Of Cardiac Muscle Hypertrophy Forebrain Development Cell Differentiation Nucleus Cis-regulatory Region Sequence-specific DNA Binding	Negative Regulation Of RNA Metabolic Process Nuclear Receptor Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Chromatin Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process DNA Binding Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Androgen Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Sequence-specific DNA Binding Chromatin Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Zinc Ion Binding Nucleus Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nucleoplasm Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Negative Regulation Of Androgen Receptor Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity P53 Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Androgen Receptor Binding Positive Regulation Of Metabolic Process Regulation Of Apoptotic Process Chromatin Organization Macromolecule Biosynthetic Process Negative Regulation Of Protein Oligomerization Regulation Of Programmed Cell Death
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