FOXP1 and ALB

Number of citations of the paper that reports this interaction (PubMedID 31623628)
49

Data Source:
BioGRID (unspecified method)

		FOXP1	ALB
Description		forkhead box P1	albumin
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Platelet Alpha Granule Lumen Protein-containing Complex Extracellular Exosome Blood Microparticle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Nuclear Androgen Receptor Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Fatty Acid Binding Copper Ion Binding Protein Binding Lipid Binding Toxic Substance Binding Antioxidant Activity Oxygen Binding Pyridoxal Phosphate Binding Identical Protein Binding Metal Ion Binding Protein-folding Chaperone Binding Exogenous Protein Binding Enterobactin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of B Cell Apoptotic Process Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II DNA Damage Response Regulation Of Gene Expression Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Gene Expression Striatum Development Osteoclast Differentiation Forebrain Development Response To Lipopolysaccharide Regulation Of Interleukin-1 Beta Production Regulation Of Interleukin-12 Production Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-21 Production Response To Testosterone Osteoclast Development Macrophage Activation Monocyte Activation Endothelial Cell Activation Regulation Of Monocyte Differentiation Negative Regulation Of DNA-templated Transcription Animal Organ Development Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Inflammatory Response Positive Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development T Follicular Helper Cell Differentiation Cellular Response To Tumor Necrosis Factor Regulation Of Defense Response To Bacterium Regulation Of Macrophage Colony-stimulating Factor Production Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Regulation Of Endothelial Tube Morphogenesis Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production	Cellular Response To Starvation Response To Nutrient Levels Negative Regulation Of Mitochondrial Depolarization Cellular Response To Calcium Ion Starvation Cellular Oxidant Detoxification
Pathways			Platelet degranulation Recycling of bile acids and salts Heme biosynthesis Heme degradation Scavenging of heme from plasma Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation HDL remodeling Cytoprotection by HMOX1 Aspirin ADME Prednisone ADME Ciprofloxacin ADME
Drugs			Amsacrine Cefotaxime Phenol Norelgestromin Aniline Guaiacol Artenimol Silver Patent Blue
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Age at first sexual intercourse ( 34211149) Anorexia nervosa ( 31308545) Apolipoprotein A1 levels ( 32203549) Arthritis (juvenile idiopathic) ( 33106285) Asthma ( 32296059) Attention deficit hyperactivity disorder ( 18821565) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Barrett's esophagus ( 24121790) Barrett's esophagus or Esophageal adenocarcinoma ( 31527586 27527254) Basal cell carcinoma ( 31174203 33549134 27539887) Beef consumption ( 32066663) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683) Childhood maltreatment ( 32066696) Chronotype ( 30696823) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Cutaneous squamous cell carcinoma ( 32041948) Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined) ( 24121790) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Eosinophil percentage of white cells ( 32888494) Esophageal adenocarcinoma ( 24121790) Familial lung adenocarcinoma ( 29924316) FEV1 ( 30804560) Gastroesophageal reflux disease ( 31527586) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Haemorrhoidal disease ( 33888516) Hand grip strength ( 29691431) Height ( 28552196) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29617998 24002674 31798171) Intraocular pressure and central corneal thickness (multi-trait analysis) ( 31798171) Keratinocyte cancer (MTAG) ( 31174203) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Lung function (FVC) ( 30804560) Lymphocyte count ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244 24076602) Nasal polyps ( 30643255) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 27863252 32888494) Non-melanoma skin cancer ( 29739929) Nose size ( 27182965) Number of sexual partners ( 30643258) Oily fish consumption ( 32066663) Optic disc size ( 31809533) Pork consumption ( 32066663) PR interval ( 32439900) Primary sclerosing cholangitis ( 27992413) Prudent dietary pattern ( 28644415) Pulse pressure ( 27841878) Red blood cell count ( 27863252 32888494) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Schizophrenia ( 30285260) Selective IgA deficiency ( 27723758) Smoking initiation ( 33082346) Squamous cell carcinoma ( 26829030) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Subcutaneous adipose tissue ( 22589738) Systolic blood pressure ( 27841878) Tooth agenesis (maxillary lateral incisors) ( 29364747) Vitiligo ( 27723757) Waist-to-hip ratio adjusted for BMI ( 34021172) Walking pace ( 33128006) White blood cell count ( 32888494)	Cholesterol ester levels in large LDL ( 29084231) Cholesterol ester levels in medium LDL ( 29084231) Esterified cholesterol levels ( 29084231) Free cholesterol levels ( 29084231) Free cholesterol levels in large LDL ( 29084231) Large LDL particle concentration ( 29084231) Lipid metabolism phenotypes ( 22286219) Medium LDL particle concentration ( 29084231) Prostate cancer ( 23535732) Serum total cholesterol levels ( 29084231) Small LDL particle concentration ( 29084231) Total cholesterol levels in large LDL ( 29084231) Total cholesterol levels in LDL ( 29084231) Total cholesterol levels in medium LDL ( 29084231) Total cholesterol levels in small LDL ( 29084231)
Interacting Genes		117 interacting genes: AKR1A1 ALB ALYREF ANLN ANXA2 AURKA BAZ2B C1QBP CCDC167 CCDC73 CDKN2AIP CHSY1 CPSF6 CSDE1 CTBP1 DCD DDX17 DDX19B DLAT DMD DOC2A ECE2 EXOG FOXP2 FOXP4 GAPDH GAR1 GOLGA2 H1-4 H2AC25 HERC1 HNRNPD HNRNPH1 HNRNPK HNRNPUL1 HSPA8 HSPB1 HYDIN IGF2BP3 IKZF1 IL3RA IQSEC2 KIF27 LRRK1 MNAT1 MTUS1 MYH7B NCOR2 NLRC4 NR2F1 NR2F2 PARN PCBP2 PCSK4 PKD1P6 POP7 PTBP1 PURA RAG2 RAN RBMS2 RBMX RGL1 RPL22 RPL23A RPL27 RPL28 RPL31 RPL35 RPL37A RPL4 RPL5 RPL6 RPS15A RPS16 RPS20 RPS27A RPS3 RUVBL1 SATB1 SATB2 SLC22A16 SMARCA2 SNRPA1 SNRPB2 SNRPC SNRPD1 SNRPD2 SNRPE SNRPF SNRPN SOX5 SRP14 SRSF1 SRSF3 SRSF8 SSBP1 STAU1 STAU2 STRAP TARBP2 TBC1D23 THUMPD1 TNFRSF1B TRA2A TUBA1B TUBA8 TYW1B UGGT1 UMPS WBP11 WDR11 WDR72 YY1 ZC3HAV1 ZDHHC16 ZMYM2	32 interacting genes: AGA AMBP APOE CRYAA CUBN F7 FCGRT FNDC3B FOXP1 HNF1A IMMT KLK3 LAMTOR5 LINC00624 LINC02582 LRP2 LUC7L2 NR5A2 ORM1 PFDN1 PON1 PRB3 RBP4 RNF181 RYR2 SRGN ST13 TK1 USP7 VWF WEE2-AS1 YWHAG
Entrez ID		27086	213
HPRD ID		18518	00062
Ensembl ID		ENSG00000114861	ENSG00000163631
Uniprot IDs		A0A0B4J2F3 A0A3B3IRW5 A0A3B3IST0 A0A3B3IT66 Q548T7 Q8N2P0 Q8TEA2 Q9H334	P02768
PDB IDs		2KIU	1AO6 1BJ5 1BKE 1BM0 1E78 1E7A 1E7B 1E7C 1E7E 1E7F 1E7G 1E7H 1E7I 1GNI 1GNJ 1H9Z 1HA2 1HK1 1HK2 1HK3 1HK4 1HK5 1N5U 1O9X 1TF0 1UOR 1YSX 2BX8 2BXA 2BXB 2BXC 2BXD 2BXE 2BXF 2BXG 2BXH 2BXI 2BXK 2BXL 2BXM 2BXN 2BXO 2BXP 2BXQ 2ESG 2I2Z 2I30 2N0X 2VDB 2VUE 2VUF 2XSI 2XVQ 2XVU 2XVV 2XVW 2XW0 2XW1 2YDF 3A73 3B9L 3B9M 3CX9 3JQZ 3JRY 3LU6 3LU7 3LU8 3SQJ 3TDL 3UIV 4BKE 4E99 4EMX 4G03 4G04 4HGK 4HGM 4IW1 4IW2 4K2C 4K71 4L8U 4L9K 4L9Q 4LA0 4LB2 4LB9 4N0F 4N0U 4S1Y 4Z69 5FUO 5GIX 5GIY 5ID7 5IFO 5IJF 5UJB 5VNW 5X52 5YB1 5YOQ 5Z0B 6A7P 6EZQ 6JE7 6L4K 6M4R 6M58 6M5D 6M5E 6QIO 6QIP 6R7S 6WUW 6XV0 6YG9 6ZL1 7A9C 7AAE 7AAI 7D6J 7DJN 7DL4 7EEK 7FFR 7FFS 7JWN 7QFE 7VR0 7VR9 7WKZ 7WLF 7WOJ 7WOK 7WZ9 7X7X 7Y2D 7Z57 8A9Q 8CKS 8EW4 8EW7 8EY5 8H0O 8ISM 8ITR 8ITT 8J8E 8K1Y 8OI2 8Q3F 8RCO 8RCP 8RGK 8RGL 8VAC 8VAE 8VAF 8Y9S 8Y9T 8Y9U 8YG7 8YXA 8YXB 8Z8V 9CSG
Enriched GO Terms of Interacting Partners?		RNA Binding Ribonucleoprotein Complex RNA Processing Cytosolic Ribosome RNA Splicing MRNA Metabolic Process MRNA Binding Nucleic Acid Metabolic Process MRNA Processing Cytoplasmic Translation RNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process RNA Splicing, Via Transesterification Reactions Structural Constituent Of Ribosome Catalytic Step 2 Spliceosome Nucleus Spliceosomal Complex Ribosome Cytosolic Large Ribosomal Subunit U1 SnRNP Nucleic Acid Binding U2 SnRNP Small Nuclear Ribonucleoprotein Complex Translation U4 SnRNP Protein-RNA Complex Assembly U2-type Prespliceosome Assembly Nucleoplasm PICln-Sm Protein Complex U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome Regulation Of MRNA Splicing, Via Spliceosome SMN-Sm Protein Complex 7-methylguanosine Cap Hypermethylation U5 SnRNP Macromolecule Biosynthetic Process Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process Spliceosomal SnRNP Assembly Negative Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Spliceosomal Complex Assembly Methylosome U2-type Precatalytic Spliceosome Nucleolus Extracellular Exosome Cytosolic Small Ribosomal Subunit Focal Adhesion	Steroid Metabolic Process Protein-containing Complex Vascular Endothelial Growth Factor Binding Extracellular Space Blood Microparticle Negative Regulation Of Multicellular Organismal Process Vascular Endothelial Growth Factor Receptor Activity Genitalia Development Vitamin Transport Cobalamin Transport Vagina Development Alcohol Metabolic Process Regulation Of Biological Quality Regulation Of Multicellular Organismal Process Regulation Of TOR Signaling Response To Reactive Oxygen Species Platelet Alpha Granule Lumen TORC1 Signaling Negative Regulation Of Amyloid Fibril Formation Regulation Of Blood Coagulation Regulation Of Hemostasis Extracellular Region Regulation Of Defense Response To Bacterium Female Genitalia Development Vitamin Transmembrane Transport Regulation Of Amyloid Fibril Formation Negative Regulation Of Platelet Activation Transcytosis Receptor Complex Vascular Endothelial Growth Factor Signaling Pathway TOR Signaling U1 SnRNP Positive Regulation Of TOR Signaling Cytochrome C Metabolic Process Antioxidant Activity Extracellular Matrix Extracellular Exosome Negative Regulation Of Phospholipid Efflux Sterol Metabolic Process Chemical Homeostasis Negative Regulation Of Gene Expression High-density Lipoprotein Particle Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Cholesterol Metabolic Process Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Positive Regulation Of Multicellular Organismal Process Calcium Ion Homeostasis Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
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