FOXP4 and FOXP1

Number of citations of the paper that reports this interaction (PMID 14701752)
56

Data Source:
HPRD (two hybrid, in vitro)

		FOXP4	FOXP1
Gene Name		forkhead box P4	forkhead box P1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Androgen Receptor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Heart Development Embryonic Foregut Morphogenesis Lung Secretory Cell Differentiation Negative Regulation Of Lung Goblet Cell Differentiation	Negative Regulation Of B Cell Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Endothelial Cell Migration Osteoclast Differentiation Response To Lipopolysaccharide Regulation Of Tumor Necrosis Factor Production Chemokine (C-C Motif) Ligand 2 Secretion Osteoclast Development Macrophage Activation Monocyte Activation Endothelial Cell Activation Regulation Of Monocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Interleukin-1 Beta Secretion Regulation Of Inflammatory Response Negative Regulation Of Androgen Receptor Signaling Pathway T Follicular Helper Cell Differentiation Interleukin-21 Secretion Regulation Of Defense Response To Bacterium Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Endothelial Tube Morphogenesis Regulation Of Interleukin-12 Secretion
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 20676098)	Attention deficit hyperactivity disorder ( 18821565) Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		2 interactors: FOXP1 FOXP2	5 interactors: CTBP1 FOXP2 FOXP4 IL3RA NCOR2
Entrez ID		116113	27086
HPRD ID		10600	18518
Ensembl ID		ENSG00000137166	ENSG00000114861
Uniprot IDs		Q8IVH2	E9PFD3 Q548T7 Q8N2P0 Q8TEA2 Q9H334
PDB IDs			2KIU
Enriched GO Terms of Interacting Partners?		Smooth Muscle Tissue Development Positive Regulation Of Mesenchymal Cell Proliferation Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Stem Cell Proliferation Regulation Of Stem Cell Proliferation Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Positive Regulation Of Epithelial Cell Proliferation Interleukin-21 Secretion Putamen Development Caudate Nucleus Development Lung Development Respiratory Tube Development Muscle Organ Development Respiratory System Development Regulation Of Epithelial Cell Proliferation Regulation Of Endothelial Tube Morphogenesis Negative Regulation Of Lung Goblet Cell Differentiation Chemokine (C-C Motif) Ligand 2 Secretion Striated Muscle Tissue Development Muscle Tissue Development Chemokine Secretion Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Interleukin-12 Secretion T Follicular Helper Cell Differentiation Vocal Learning Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Muscle Structure Development Righting Reflex Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Monocyte Activation Immunoglobulin V(D)J Recombination Osteoclast Development Chemokine Production Auditory Behavior Regulation Of Defense Response To Bacterium Pre-B Cell Differentiation Negative Regulation Of B Cell Apoptotic Process Tube Development Endothelial Cell Activation Immature B Cell Differentiation Lung Secretory Cell Differentiation Negative Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Monocyte Differentiation Positive Regulation Of Cell Proliferation Striatum Development Transcription From RNA Polymerase II Promoter Mechanosensory Behavior Positive Regulation Of Cardiac Muscle Cell Differentiation	White Fat Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Lung Development Respiratory Tube Development Respiratory System Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Lung Epithelial Cell Differentiation Lung Cell Differentiation Lung Epithelium Development Regulation Of Transcription From RNA Polymerase II Promoter Putamen Development Caudate Nucleus Development Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Tube Development Fat Cell Differentiation Negative Regulation Of Cellular Metabolic Process Interleukin-3-mediated Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Lung Goblet Cell Differentiation Vocal Learning Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Cellular Response To Interleukin-3 Righting Reflex Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Telencephalon Development RNA Metabolic Process Negative Regulation Of Histone H4 Acetylation Gene Expression Auditory Behavior Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Lung Secretory Cell Differentiation Striatum Development Forebrain Development Tissue Development Regulation Of Histone H4 Acetylation Mechanosensory Behavior Type I Pneumocyte Differentiation Response To Auditory Stimulus Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Histone Deacetylation Negative Regulation Of Histone Acetylation Heart Development
Tagcloud ?		ahcy arrays bac balanced breakpoints breaks ctcf dismissed ep300 fusions hcc1187 hcc1806 hybridized idea mapped microarrays oligonucleotide painting participating path pkd1l1 plausible reciprocal rif1 tax1bp1 tiling translocations unbalanced zr	3p amplifications breeding classic consuming cooperates costly daunting drive drivers driving endogenously engineering faithful hidden incurable pc pten ptenloxp rapidcap recreate reside rybp sensitized shq1 trp53 trp53loxp unmet validation
Tagcloud (Difference) ?		ahcy arrays bac balanced breakpoints breaks ctcf dismissed ep300 fusions hcc1187 hcc1806 hybridized idea mapped microarrays oligonucleotide painting participating path pkd1l1 plausible reciprocal rif1 tax1bp1 tiling translocations unbalanced zr	3p amplifications breeding classic consuming cooperates costly daunting drive drivers driving endogenously engineering faithful hidden incurable pc pten ptenloxp rapidcap recreate reside rybp sensitized shq1 trp53 trp53loxp unmet validation
Tagcloud (Intersection) ?