FOXP4 and SOX5

Number of citations of the paper that reports this interaction (PubMedID 29365100)
0

Data Source:
BioGRID (fluorescent resonance energy transfer)

		FOXP4	SOX5
Description		forkhead box P4	SRY-box transcription factor 5
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Cartilage Condensation Chondrocyte Differentiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Chondrocyte Differentiation Cell Fate Commitment Cartilage Development Asymmetric Neuroblast Division Positive Regulation Of Cartilage Development Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Mesenchymal Stem Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) EGFR mutation-positive lung adenocarcinoma ( 27501781) Fasting insulin ( 34059833) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Metabolite levels ( 23823483) Non-small cell lung cancer ( 31326317) Prostate cancer ( 20676098 31562322)	Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) AIDS ( 19754311) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Appendicular lean mass ( 33097823) Attention deficit hyperactivity disorder ( 29325848) Body mass index ( 25673413) Chronic back pain ( 30261039) Chronotype ( 30696823) Creatinine levels ( 29403010) Depression ( 29700475) Glomerular filtration rate ( 29403010) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise ( 29769521) Heel bone mineral density ( 30598549) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 27569725) Juvenile osteochondritis dissecans ( 26422391) LDL peak particle diameter (total fat intake interaction) ( 26112879) Mortality in sepsis ( 27639821) Multisite chronic pain ( 33830993) Non-obstructive azoospermia ( 22197933) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Pelvic organ prolapse (moderate/severe) ( 26545240) PR interval ( 30046033 20062060 29127183 32439900) Response to antipsychotic treatment ( 20195266) Response to statin therapy ( 20339536) Resting heart rate ( 29769521 27798624) Schizophrenia ( 29483656) Systemic sclerosis ( 21779181) Systolic blood pressure ( 30224653) T wave morphology restitution during exercise ( 31607149) T wave morphology restitution during exercise (MTAG) ( 31607149) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		10 interacting genes: FOXP1 FOXP2 NR2F1 NR2F2 SATB1 SATB2 SOX5 XAGE2 YY1 ZMYM2	42 interacting genes: APP ARID5A BIRC7 CAMK2A CBX8 CDC23 CDC25A CDK6 CRX FOXP1 FOXP2 FOXP4 FTH1 FXR1 HNF1B KAT5 KIFC3 LMO1 LMO2 MAGED1 MED27 MORN3 MSX2 NFIC NFIX PIAS2 PRR20A RNF4 RPS2 SMAD1 SMAD5 SMAD7 SOX6 SUMO1P1 TENT5B TEX11 TRAF2 TTC1 UBE2I UQCRFS1 ZBTB26 ZNF581
Entrez ID		116113	6660
HPRD ID		10600	18086
Ensembl ID		ENSG00000137166	ENSG00000134532
Uniprot IDs		B7ZBM3 Q8IVH2	F5H0I3 P35711 T2CYZ2
PDB IDs		6XAT
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Activity Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Negative Regulation Of Metabolic Process Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Nuclear Matrix Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of Cardiac Muscle Tissue Growth Negative Regulation Of Organ Growth Nuclear Lumen Negative Regulation Of Cardiac Muscle Hypertrophy Regulation Of Macromolecule Metabolic Process Negative Regulation Of Muscle Hypertrophy Negative Regulation Of Striated Muscle Cell Differentiation Cellular Developmental Process Zinc Ion Binding Nuclear Receptor Activity Regulation Of Metabolic Process Radial Pattern Formation Putamen Development Caudate Nucleus Development Animal Organ Development Skeletal Muscle Tissue Development Regulation Of Heart Growth Negative Regulation Of Muscle Cell Differentiation Regulation Of Cardiac Muscle Hypertrophy Forebrain Development Cell Differentiation Nucleus Cis-regulatory Region Sequence-specific DNA Binding	Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Transcription Regulator Complex Regulation Of Macromolecule Metabolic Process Chromatin Nucleus Regulation Of Gene Expression Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process SMAD Protein Signal Transduction Heteromeric SMAD Protein Complex DNA-binding Transcription Factor Activity RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Metabolic Process Nucleoplasm Transcription Coregulator Binding Positive Regulation Of Biosynthetic Process Mesonephric Tubule Development Positive Regulation Of Nucleobase-containing Compound Metabolic Process Mesonephric Epithelium Development I-SMAD Binding Cardiac Conduction System Development Stem Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process DNA Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Programmed Cell Death Transcription Factor Binding Osteoblast Fate Commitment Striated Muscle Tissue Development Identical Protein Binding Epithelium Development Kidney Epithelium Development Positive Regulation Of RNA Metabolic Process Mitotic Cell Cycle Phase Transition Muscle Tissue Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?