FOXP4

Name	forkhead box P4
Structure
Interactors	10 interactors: FOXP1 FOXP2 NR2F1 NR2F2 SATB1 SATB2 SOX5 XAGE2 YY1 ZMYM2
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
GWAS	Chronotype ( 30696823 ) EGFR mutation-positive lung adenocarcinoma ( 27501781 ) Fasting insulin ( 34059833 ) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223 ) High light scatter reticulocyte count ( 32888494 ) High light scatter reticulocyte percentage of red cells ( 32888494 ) Metabolite levels ( 23823483 ) Non-small cell lung cancer ( 31326317 ) Prostate cancer ( 20676098 31562322 )
Entrez ID	116113
HPRD ID	10600
Ensembl ID	ENSG00000137166
Uniprot IDs	B7ZBM3 Q8IVH2
PDB IDs	6XAT
GO Terms Enriched among Interactors ?	DNA-binding Transcription Factor Activity Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Negative Regulation Of Metabolic Process Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Nuclear Matrix Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of Cardiac Muscle Tissue Growth Negative Regulation Of Organ Growth Nuclear Lumen Negative Regulation Of Cardiac Muscle Hypertrophy Regulation Of Macromolecule Metabolic Process Negative Regulation Of Muscle Hypertrophy Negative Regulation Of Striated Muscle Cell Differentiation Cellular Developmental Process Zinc Ion Binding Nuclear Receptor Activity Regulation Of Metabolic Process Radial Pattern Formation Putamen Development Caudate Nucleus Development Animal Organ Development Skeletal Muscle Tissue Development Regulation Of Heart Growth Negative Regulation Of Muscle Cell Differentiation Regulation Of Cardiac Muscle Hypertrophy Forebrain Development Cell Differentiation Nucleus Cis-regulatory Region Sequence-specific DNA Binding