CYFIP2 and ABI3

Number of citations of the paper that reports this interaction (PMID 17101133)
6

Data Source:
HPRD (in vivo)

		CYFIP2	ABI3
Gene Name		cytoplasmic FMR1 interacting protein 2	ABI family, member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Membrane Cell Junction Neuron Projection Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Intracellular Cytoplasm Membrane Lamellipodium
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Apoptotic Process Single Organismal Cell-cell Adhesion Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Positive Regulation Of Proteolysis Vascular Endothelial Growth Factor Receptor Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity	Movement Of Cell Or Subcellular Component Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration
Pathways		Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		20 interactors: ABI1 ABI3 APBB1 BIRC3 BRK1 DNMBP FMR1 FXR1 FXR2 GAS7 NCK1 NCKAP1 PLG PRPF40A SMAD4 TCERG1 WASF1 WASF2 YWHAG ZC3H12A	36 interactors: ABI3BP ACTN3 ARMC7 CEP170P1 CEP44 CYFIP2 DTNB DTNBP1 EIF3H ENAH EVL FARSA FBF1 GRB2 HOMER1 HOMER3 KANK2 KIAA0408 KLC3 KLC4 KRT13 KRT15 MAGEA12 MRFAP1L1 NCK2 NUPL1 PAK1 PAK2 PSMA1 RUNX1T1 SNAP23 SOS1 TMEM147 VASP WAS WASF2
Entrez ID		26999	51225
HPRD ID		07556	05900
Ensembl ID		ENSG00000055163	ENSG00000108798
Uniprot IDs		E7EVJ5 E7EW33 F5H583 Q96F07	Q9P2A4
PDB IDs
Enriched GO Terms of Interacting Partners?		Rac Protein Signal Transduction Movement Of Cell Or Subcellular Component Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Lamellipodium Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Lamellipodium Assembly Negative Regulation Of Protein Metabolic Process Actin Cytoskeleton Organization Positive Regulation Of Lamellipodium Organization Actin Filament-based Process Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Cellular Component Organization Regulation Of Actin Nucleation Regulation Of Lamellipodium Assembly Regulation Of Cellular Process Immune Response-regulating Signaling Pathway Cytoskeleton Organization Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Locomotion Cell Motility Lamellipodium Morphogenesis Negative Regulation Of Biosynthetic Process Lamellipodium Assembly Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Multicellular Organismal Development Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Anatomical Structure Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cytoskeleton Organization System Development Cell Projection Organization Regulation Of Protein Metabolic Process Posttranscriptional Regulation Of Gene Expression Ras Protein Signal Transduction Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Somitogenesis Cell Migration Cell Projection Morphogenesis Regulation Of Cytoskeleton Organization Negative Regulation Of Translation	Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Projection Morphogenesis Cell Part Morphogenesis Immune Response-regulating Signaling Pathway Movement Of Cell Or Subcellular Component Axon Guidance Cell Morphogenesis Fc Receptor Signaling Pathway Neuron Projection Morphogenesis Actin Filament-based Process Cell Projection Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Cytoskeleton Organization Axonogenesis Regulation Of Actin Cytoskeleton Organization T Cell Receptor Signaling Pathway Axon Development Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Actin Filament-based Process Actin Cytoskeleton Organization Chemotaxis Regulation Of Immune Response Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Neuron Development Cell Morphogenesis Involved In Differentiation Positive Regulation Of Cellular Component Biogenesis Regulation Of Cytoskeleton Organization Regulation Of Immune System Process Actin Polymerization Or Depolymerization Immune System Process Neuron Differentiation Cytoskeleton Organization Cell Development Cell Surface Receptor Signaling Pathway Positive Regulation Of Organelle Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Locomotion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Anatomical Structure Morphogenesis Phagocytosis Actin Filament Organization Innate Immune Response
Tagcloud ?		als amyotrophic beacons biomarkers creating discovered etiology fals familial fatal g93a hmsc inherited leukocyte msod1 ones path pathogenetic pave rbbp9 sals secretory share signature slpi sod1 spatiotemporal sporadic tar	abbreviated cfp chose clustered confirming cotyledons derepressing detail egfp embryo embryogenesis embryos exemplified files fus3 germinating germinative globular heterochronic lec lec1 lec2 misexpression pyk10 reporter repressing seedling seedlings stochastic
Tagcloud (Difference) ?		als amyotrophic beacons biomarkers creating discovered etiology fals familial fatal g93a hmsc inherited leukocyte msod1 ones path pathogenetic pave rbbp9 sals secretory share signature slpi sod1 spatiotemporal sporadic tar	abbreviated cfp chose clustered confirming cotyledons derepressing detail egfp embryo embryogenesis embryos exemplified files fus3 germinating germinative globular heterochronic lec lec1 lec2 misexpression pyk10 reporter repressing seedling seedlings stochastic
Tagcloud (Intersection) ?