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KAT2A and H4C7
Number of citations of the paper that reports this interaction (PubMedID
35907431
)
0
Data Source:
BioGRID
(enzymatic study)
KAT2A
H4C7
Description
lysine acetyltransferase 2A
H4 clustered histone 7
Image
No pdb structure
GO Annotations
Cellular Component
Histone Acetyltransferase Complex
SAGA Complex
Chromatin
Extracellular Space
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Centrosome
Cytoskeleton
Transcription Factor TFTC Complex
Oxoglutarate Dehydrogenase Complex
Mitotic Spindle
ATAC Complex
Nucleosome
Nucleus
Chromosome
Molecular Function
Chromatin Binding
Transcription Coactivator Activity
Histone Acetyltransferase Activity
Protein Binding
N-acetyltransferase Activity
Histone H3 Acetyltransferase Activity
Acetyltransferase Activity
Transferase Activity
Acyltransferase Activity
Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups
Protein Phosphatase Binding
Histone Deacetylase Binding
Histone H3K9 Acetyltransferase Activity
Histone H3K18 Acetyltransferase Activity
Histone H4K12 Acetyltransferase Activity
Protein-lysine-acetyltransferase Activity
Histone Succinyltransferase Activity
Peptide Glutaryltransferase Activity
Histone Glutaryltransferase Activity
DNA-binding Transcription Factor Binding
DNA Binding
Protein Binding
Structural Constituent Of Chromatin
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
Somitogenesis
Positive Regulation Of Cytokine Production
Neural Tube Closure
Gluconeogenesis
Regulation Of DNA Repair
Chromatin Remodeling
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Heart Development
Long-term Memory
Regulation Of Gene Expression
Internal Peptidyl-lysine Acetylation
Telencephalon Development
Metencephalon Development
Midbrain Development
Positive Regulation Of Cell Projection Organization
Regulation Of Protein Stability
Response To Nutrient Levels
Multicellular Organism Growth
Protein Modification Process
Regulation Of RNA Splicing
Regulation Of Regulatory T Cell Differentiation
Negative Regulation Of Gluconeogenesis
Positive Regulation Of Gluconeogenesis
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Embryonic Development
Negative Regulation Of Centriole Replication
Fibroblast Proliferation
Regulation Of Synaptic Plasticity
Intracellular Distribution Of Mitochondria
Regulation Of T Cell Activation
Regulation Of Cell Division
Regulation Of Cell Cycle
Limb Development
Regulation Of Cartilage Development
Regulation Of Small Molecule Metabolic Process
Cellular Response To Tumor Necrosis Factor
Peptidyl-lysine Glutarylation
Regulation Of Bone Development
Cellular Response To Nerve Growth Factor Stimulus
Regulation Of Stem Cell Population Maintenance
Positive Regulation Of Cardiac Muscle Cell Differentiation
Nucleosome Assembly
Pathways
Pre-NOTCH Transcription and Translation
Pre-NOTCH Transcription and Translation
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
NOTCH1 Intracellular Domain Regulates Transcription
NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
HATs acetylate histones
Notch-HLH transcription pathway
B-WICH complex positively regulates rRNA expression
Ub-specific processing proteases
RNA Polymerase I Transcription Initiation
RUNX3 regulates NOTCH signaling
RUNX3 regulates NOTCH signaling
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH4 Intracellular Domain Regulates Transcription
Cardiogenesis
Formation of WDR5-containing histone-modifying complexes
Formation of paraxial mesoderm
Drugs
Coenzyme A
Diseases
GWAS
Coronary artery disease (
29212778
33020668
)
Inflammatory bowel disease (
26278503
)
Mean reticulocyte volume (
32888494
)
Vitiligo (
27723757
)
vWF and FVIII levels (
30586737
)
Interacting Genes
67 interacting genes:
AKT1
ATXN7
BATF2
BECN1
CCND2
CCNE1
CDK2
CDK6
CDKN2B
CEBPA
CEBPB
COMMD1
CREBBP
CRX
CTNNB1
CUL2
DTL
ECHS1
EID1
EP300
FZR1
GATA2
GRM1
H1-5
H2AC20
H2AC4
H2BC21
H2BC3
H3-4
H3C1
H3C14
H4C14
H4C16
H4C7
HSD11B2
IRF1
IRF2
IRF7
KDELR2
LATS2
MAP2K3
MAPK14
MYB
MYC
NF2
NOTCH1
PBX1
PRKDC
PYGO2
RASSF1
RBPJ
RELA
RPA1
SIRT2
SNCA
STK11
TACC1
TACC2
TACC3
TADA2A
TCF3
TP53
TRRAP
TSC1
TTYH2
UBE2I
XRCC6
13 interacting genes:
AGTRAP
APOC1
CIDEB
EP300
FGF14
FKBP7
KAT2A
KAT8
KMT5B
KMT5C
MAIP1
RHBDD2
TMED8
Entrez ID
2648
8369
HPRD ID
03807
11806
Ensembl ID
ENSG00000108773
ENSG00000275663
Uniprot IDs
Q92830
Q99525
PDB IDs
1F68
1Z4R
3D7C
5H84
5H86
5MLJ
5TRL
5TRM
6J3P
8E6O
8H65
8H66
8H6C
8H6D
Enriched GO Terms of Interacting Partners
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Nucleus
Nucleoplasm
Regulation Of Cell Cycle
Regulation Of Cell Population Proliferation
Structural Constituent Of Chromatin
Nucleosome
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Development
Regulation Of Transcription By RNA Polymerase II
Chromatin Remodeling
Chromatin Organization
Transcription Regulator Complex
Positive Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of DNA-templated Transcription
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Cellular Response To Stress
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of RNA Metabolic Process
DNA Binding
Negative Regulation Of Metabolic Process
Regulation Of Cell Cycle Process
Chromatin Binding
Regulation Of RNA Metabolic Process
Regulation Of Cell Differentiation
Protein Heterodimerization Activity
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Hemopoiesis
DNA-binding Transcription Factor Binding
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Transcription By RNA Polymerase II
Leukocyte Differentiation
Negative Regulation Of Macromolecule Metabolic Process
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Positive Regulation Of Metabolic Process
Regulation Of Multicellular Organismal Development
Mitotic Cell Cycle Phase Transition
Mononuclear Cell Differentiation
Nucleosome Assembly
Regulation Of Nucleobase-containing Compound Metabolic Process
Response To UV
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Cell Cycle Phase Transition
Chromosome
Histone Acetyltransferase Complex
Protein Propionyltransferase Activity
Protein-lysine-acetyltransferase Activity
Acetyltransferase Activity
Histone H3K18 Acetyltransferase Activity
Histone Acetyltransferase Activity
Histone H4K20me Methyltransferase Activity
Histone H4K20 Monomethyltransferase Activity
Histone H4 Methyltransferase Activity
Histone H4K20 Methyltransferase Activity
Histone H3 Acetyltransferase Activity
Internal Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Very-low-density Lipoprotein Particle Assembly
Histone H4 Acetyltransferase Activity
Peptidyl-lysine Acetylation
Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Negative Regulation Of Small Molecule Metabolic Process
Chromatin Remodeling
Condensed Chromosome, Centromeric Region
Negative Regulation Of Gluconeogenesis
Chromosome
Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
S-adenosyl-L-methionine Binding
Positive Regulation Of Adaptive Immune Response
Plasma Lipoprotein Particle Assembly
Protein-lipid Complex Assembly
Acyltransferase Activity
Positive Regulation Of Isotype Switching
Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Chromatin Organization
Protein Acetylation
DNA-binding Transcription Factor Binding
Chromatin Binding
Regulation Of Isotype Switching
Regulation Of Triglyceride Metabolic Process
Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Positive Regulation Of Immunoglobulin Mediated Immune Response
Negative Regulation Of Phosphatidylcholine Catabolic Process
Positive Regulation Of Gene Expression, Epigenetic
Somitogenesis
Peptidyl-lysine Propionylation
Segmentation
Regulation Of Lymphocyte Activation
Swimming
Histone Lactyltransferase (CoA-dependent) Activity
Gluconeogenesis
Peptidyl-lysine Butyrylation
Peptidyl-lysine Crotonylation
Histone H3K122 Acetyltransferase Activity
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Tagcloud (Intersection)
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