H4C7 and TMED8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		H4C7	TMED8
Description		H4 clustered histone 7	transmembrane p24 trafficking protein family member 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleosome Nucleus Chromosome
	Molecular Function	DNA Binding Protein Binding Structural Constituent Of Chromatin Protein Heterodimerization Activity	Protein Binding
	Biological Process	Nucleosome Assembly
Pathways
Drugs
Diseases
GWAS
Interacting Genes		13 interacting genes: AGTRAP APOC1 CIDEB EP300 FGF14 FKBP7 KAT2A KAT8 KMT5B KMT5C MAIP1 RHBDD2 TMED8	32 interacting genes: ADTRP AMIGO2 APOL2 ARL6IP1 C10orf67 CIAO2A CMTM5 CMTM6 CYB561D1 DEFB129 DERL1 DGAT2L6 EI24 H4C7 LAPTM4A MDK MMGT1 MRPL41 MRPS18B MTIF3 NDUFA12 REEP6 SERP2 STX8 SUSD3 TMEM115 TMEM121 TMEM218 TMEM254 TRAM1L1 UNC50 ZDHHC16
Entrez ID		8369	283578
HPRD ID		11806	18201
Ensembl ID		ENSG00000275663	ENSG00000100580
Uniprot IDs		Q99525	Q6PL24
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone Acetyltransferase Complex Protein Propionyltransferase Activity Protein-lysine-acetyltransferase Activity Acetyltransferase Activity Histone H3K18 Acetyltransferase Activity Histone Acetyltransferase Activity Histone H4K20me Methyltransferase Activity Histone H4K20 Monomethyltransferase Activity Histone H4 Methyltransferase Activity Histone H4K20 Methyltransferase Activity Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Very-low-density Lipoprotein Particle Assembly Histone H4 Acetyltransferase Activity Peptidyl-lysine Acetylation Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of Small Molecule Metabolic Process Chromatin Remodeling Condensed Chromosome, Centromeric Region Negative Regulation Of Gluconeogenesis Chromosome Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains S-adenosyl-L-methionine Binding Positive Regulation Of Adaptive Immune Response Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Acyltransferase Activity Positive Regulation Of Isotype Switching Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Chromatin Organization Protein Acetylation DNA-binding Transcription Factor Binding Chromatin Binding Regulation Of Isotype Switching Regulation Of Triglyceride Metabolic Process Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Regulation Of Immunoglobulin Mediated Immune Response Negative Regulation Of Phosphatidylcholine Catabolic Process Positive Regulation Of Gene Expression, Epigenetic Somitogenesis Peptidyl-lysine Propionylation Segmentation Regulation Of Lymphocyte Activation Swimming Histone Lactyltransferase (CoA-dependent) Activity Gluconeogenesis Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity	Endoplasmic Reticulum Membrane
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