BLOC1S1 and BLOC1S2

Number of citations of the paper that reports this interaction (PMID 15102850)
57

Data Source:
HPRD (two hybrid)

		BLOC1S1	BLOC1S2
Gene Name		biogenesis of lysosomal organelles complex-1, subunit 1	biogenesis of lysosomal organelles complex-1, subunit 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Mitochondrial Intermembrane Space Mitochondrial Matrix Lysosomal Membrane Cytosol BLOC-1 Complex Extracellular Vesicular Exosome	Gamma-tubulin Complex Nucleus Mitochondrion Centrosome BLOC-1 Complex Recycling Endosome
	Molecular Function	Protein Binding	Protein Binding Protein C-terminus Binding Gamma-tubulin Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Aerobic Respiration Peptidyl-lysine Acetylation Neuron Projection Development Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Membrane Organization	Microtubule Nucleation Anterograde Axon Cargo Transport Positive Regulation Of Cell Proliferation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Neuron Projection Development Melanosome Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: APP BLOC1S2 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 HIST1H4A MTA1 NOTCH1 PBX2 PELP1 PTN SNAPIN	15 interactors: APP BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 FAM9B HMOX2 MEST PAM16 RDH11 SNAPIN TNNT1 WASH1
Entrez ID		2647	282991
HPRD ID		03263	12526
Ensembl ID		ENSG00000135441
Uniprot IDs		P78537	F1T0F0 Q6QNY1
PDB IDs
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Axon Cargo Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Movement Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Neuron Projection Development Neuron Development Endosome To Melanosome Transport Pigment Granule Maturation Establishment Of Organelle Localization Cellular Pigment Accumulation Neuron Differentiation Cell Projection Organization Organelle Localization Microtubule-based Process Movement Of Cell Or Subcellular Component Synaptic Transmission Generation Of Neurons Nervous System Development Neurogenesis Melanosome Transport Pigment Granule Transport Cell Development Establishment Of Melanosome Localization Melanosome Localization Establishment Of Localization In Cell Secretion Of Lysosomal Enzymes Vesicle-mediated Transport Endosomal Transport Cell-cell Signaling Secretion By Cell Developmental Pigmentation Intracellular Transport Cellular Localization Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Platelet Dense Granule Organization Wound Healing Post-Golgi Vesicle-mediated Transport Secretion Multicellular Organismal Development Positive Regulation Of Pigment Cell Differentiation	Anterograde Synaptic Vesicle Transport Axon Cargo Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Movement Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Pigment Granule Maturation Endosome To Melanosome Transport Establishment Of Organelle Localization Intracellular Transport Cellular Pigment Accumulation Organelle Localization Microtubule-based Process Endosomal Transport Neuron Projection Development Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Neuron Development Synaptic Transmission Cellular Localization Neuron Differentiation Cell Projection Organization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Secretion Of Lysosomal Enzymes Cell-cell Signaling Secretion By Cell Developmental Pigmentation Generation Of Neurons Neurogenesis Golgi Vesicle Transport Platelet Dense Granule Organization Secretion Cell Development Positive Regulation Of Pigment Cell Differentiation Cytoplasmic Transport Transport Exocytosis
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