BLOC1S1 and BLOC1S5

Number of citations of the paper that reports this interaction (PMID 15102850)
57

Data Source:
HPRD (two hybrid)

		BLOC1S1	BLOC1S5
Gene Name		biogenesis of lysosomal organelles complex-1, subunit 1	biogenesis of lysosomal organelles complex-1, subunit 5, muted
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Mitochondrial Intermembrane Space Mitochondrial Matrix Lysosomal Membrane Cytosol BLOC-1 Complex Extracellular Vesicular Exosome	Transport Vesicle BLOC-1 Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Aerobic Respiration Peptidyl-lysine Acetylation Neuron Projection Development Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Membrane Organization	Anterograde Axon Cargo Transport Neuron Projection Development Melanosome Transport Melanosome Organization Otolith Morphogenesis Endosome To Melanosome Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: APP BLOC1S2 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 HIST1H4A MTA1 NOTCH1 PBX2 PELP1 PTN SNAPIN	7 interactors: APP BLOC1S1 BLOC1S2 BLOC1S4 DTNBP1 SNAPIN TSNAX
Entrez ID		2647	63915
HPRD ID		03263	06289
Ensembl ID		ENSG00000135441	ENSG00000188428
Uniprot IDs		P78537	Q8TDH9
PDB IDs
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Axon Cargo Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Movement Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Neuron Projection Development Neuron Development Endosome To Melanosome Transport Pigment Granule Maturation Establishment Of Organelle Localization Cellular Pigment Accumulation Neuron Differentiation Cell Projection Organization Organelle Localization Microtubule-based Process Movement Of Cell Or Subcellular Component Synaptic Transmission Generation Of Neurons Nervous System Development Neurogenesis Melanosome Transport Pigment Granule Transport Cell Development Establishment Of Melanosome Localization Melanosome Localization Establishment Of Localization In Cell Secretion Of Lysosomal Enzymes Vesicle-mediated Transport Endosomal Transport Cell-cell Signaling Secretion By Cell Developmental Pigmentation Intracellular Transport Cellular Localization Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Platelet Dense Granule Organization Wound Healing Post-Golgi Vesicle-mediated Transport Secretion Multicellular Organismal Development Positive Regulation Of Pigment Cell Differentiation	Axon Cargo Transport Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Microtubule-based Movement Synaptic Vesicle Transport Pigmentation Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Platelet Dense Granule Organization Microtubule-based Process Establishment Of Organelle Localization Neuron Projection Development Neuron Development Organelle Localization Neuron Differentiation Cell Projection Organization Secretory Granule Organization Synaptic Transmission Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Intracellular Transport Generation Of Neurons Neurogenesis Membrane Organization Cell Development Cell Differentiation Cell-cell Signaling Post-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Nervous System Development Cellular Localization Multicellular Organismal Development Transport Developmental Process Golgi Vesicle Transport System Development Blood Coagulation Hemostasis Endomembrane System Organization Neuromuscular Process Controlling Balance Positive Regulation Of Late Endosome To Lysosome Transport Anatomical Structure Development Regulation Of Body Fluid Levels Wound Healing
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