BLOC1S1 and BLOC1S3

Number of citations of the paper that reports this interaction (PMID 15102850)
57

Data Source:
HPRD (in vivo, two hybrid)

		BLOC1S1	BLOC1S3
Gene Name		biogenesis of lysosomal organelles complex-1, subunit 1	biogenesis of lysosomal organelles complex-1, subunit 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Mitochondrial Intermembrane Space Mitochondrial Matrix Lysosomal Membrane Cytosol BLOC-1 Complex Extracellular Vesicular Exosome	Cytosol Transport Vesicle BLOC-1 Complex
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Aerobic Respiration Peptidyl-lysine Acetylation Neuron Projection Development Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Membrane Organization	Eye Development Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Platelet Activation Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Endosome To Melanosome Transport Response To Drug Pigmentation Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Membrane Organization
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS			Quantitative traits ( 19197348)
Protein-Protein Interactions		13 interactors: APP BLOC1S2 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 HIST1H4A MTA1 NOTCH1 PBX2 PELP1 PTN SNAPIN	2 interactors: BLOC1S1 BLOC1S2
Entrez ID		2647	388552
HPRD ID		03263	12527
Ensembl ID		ENSG00000135441	ENSG00000189114
Uniprot IDs		P78537	Q6QNY0
PDB IDs
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Axon Cargo Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Movement Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Neuron Projection Development Neuron Development Endosome To Melanosome Transport Pigment Granule Maturation Establishment Of Organelle Localization Cellular Pigment Accumulation Neuron Differentiation Cell Projection Organization Organelle Localization Microtubule-based Process Movement Of Cell Or Subcellular Component Synaptic Transmission Generation Of Neurons Nervous System Development Neurogenesis Melanosome Transport Pigment Granule Transport Cell Development Establishment Of Melanosome Localization Melanosome Localization Establishment Of Localization In Cell Secretion Of Lysosomal Enzymes Vesicle-mediated Transport Endosomal Transport Cell-cell Signaling Secretion By Cell Developmental Pigmentation Intracellular Transport Cellular Localization Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Platelet Dense Granule Organization Wound Healing Post-Golgi Vesicle-mediated Transport Secretion Multicellular Organismal Development Positive Regulation Of Pigment Cell Differentiation	Platelet Dense Granule Organization Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Secretory Granule Organization Axon Cargo Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Microtubule-based Movement Establishment Of Organelle Localization Organelle Localization Endomembrane System Organization Synaptic Transmission Mitochondrial Outer Membrane Permeabilization Microtubule-based Process Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Neuron Projection Development Membrane Organization Cell-cell Signaling Positive Regulation Of Mitochondrial Membrane Permeability Neuron Development Microtubule Nucleation Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Microtubule Polymerization Neuron Differentiation Cell Projection Organization Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Microtubule Polymerization Or Depolymerization Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Intracellular Transport Generation Of Neurons Neurogenesis Aerobic Respiration Mitochondrial Membrane Organization Cell Development Apoptotic Mitochondrial Changes Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Extrinsic Apoptotic Signaling Pathway Protein Polymerization
Tagcloud ?			apoe bin1 clu comprising correcting cr1 dataset eleven epistatic epsilon4 europe exoc3l2 fisher genotyped gwas load mark4 meta modifier near picalm replicated rs11136000 rs3818361 rs3851179 rs597668 rs744373 suggestive usa
Tagcloud (Difference) ?			apoe bin1 clu comprising correcting cr1 dataset eleven epistatic epsilon4 europe exoc3l2 fisher genotyped gwas load mark4 meta modifier near picalm replicated rs11136000 rs3818361 rs3851179 rs597668 rs744373 suggestive usa
Tagcloud (Intersection) ?