GNL3 and ASCC2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GNL3	ASCC2
Gene Name		guanine nucleotide binding protein-like 3 (nucleolar)	activating signal cointegrator 1 complex subunit 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Nucleolus Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Poly(A) RNA Binding
	Biological Process	Metabolic Process Cell Proliferation Regulation Of Cell Proliferation Ribosome Biogenesis	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Adiponectin levels ( 22479202) Bipolar disorder ( 21926972) Bipolar disorder (mood-incongruent) ( 23092984) Osteoarthritis ( 22763110)
Protein-Protein Interactions		5 interactors: ASCC2 MDM2 PPP2R5A STAT3 TP53	38 interactors: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT JUN KDM1A LPL MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 RADIL RELA RNF11 RPA1 RPLP1 SNRPB SNW1 SRF TBC1D17 TRIP4 URM1
Entrez ID		26354	84164
HPRD ID		06419	16515
Ensembl ID		ENSG00000163938	ENSG00000100325
Uniprot IDs		Q9BVP2	Q9H1I8
PDB IDs			2DI0
Enriched GO Terms of Interacting Partners?		Protein Localization To Nucleus Regulation Of Signal Transduction By P53 Class Mediator DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Cellular Response To UV Signal Transduction Involved In Cell Cycle Checkpoint Response To Antibiotic Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Response To Drug Protein Localization To Organelle DNA Damage Response, Signal Transduction By P53 Class Mediator Viral Process Cellular Response To Growth Factor Stimulus Signal Transduction In Response To DNA Damage Cellular Response To Light Stimulus Regulation Of Cell Cycle Arrest Mitotic DNA Damage Checkpoint Response To Growth Factor Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Hypoxia Mitotic DNA Integrity Checkpoint Cellular Response To Decreased Oxygen Levels Cellular Response To UV-C Cellular Response To Vitamin B1 Cellular Response To Oxygen Levels Signal Transduction By P53 Class Mediator Regulation Of Establishment Of Protein Localization Protein Import Into Nucleus Nuclear Import Negative Regulation Of Cellular Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Response To UV Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Radiation Negative Regulation Of Catalytic Activity Regulation Of Protein Localization Negative Regulation Of Mitotic Cell Cycle Phase Transition DNA Damage Checkpoint Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Protein Import Mitotic Cell Cycle Checkpoint Enzyme Linked Receptor Protein Signaling Pathway Response To Toxic Substance Cellular Response To Nutrient Levels	Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Myeloid Leukocyte Differentiation RNA Metabolic Process Nitrogen Compound Metabolic Process Myeloid Cell Differentiation Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation By Host Of Viral Transcription Leukocyte Differentiation RNA Biosynthetic Process Metabolic Process Response To Abiotic Stimulus Mitochondrion Organization Hemopoiesis Monocyte Differentiation Transcription, DNA-templated Telomere Maintenance Via Semi-conservative Replication Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Platelet Formation Protein Tetramerization Response To Radiation Platelet Morphogenesis Immune System Development Macromolecule Biosynthetic Process Telomere Maintenance Via Recombination Regulation Of Histone H3-K4 Methylation Nuclear DNA Replication Positive Regulation Of Transcription, DNA-templated Response To CAMP Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Response To Drug DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Response To Stress Gene Expression Blood Vessel Endothelial Cell Migration Interaction With Symbiont Learning Membrane Protein Proteolysis Aging Regulation Of Cell Proliferation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Organophosphorus Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?		argues biogenesis card commentary conflicting contradictory dependency explains guanine incurring invertebrate notion nucleolar nucleolus nucleostemin perturbation pointed quintessential reconciled refuted renew ribosomes safeguarding signifies story tantalizing tasking trait unexpected
Tagcloud (Difference) ?		argues biogenesis card commentary conflicting contradictory dependency explains guanine incurring invertebrate notion nucleolar nucleolus nucleostemin perturbation pointed quintessential reconciled refuted renew ribosomes safeguarding signifies story tantalizing tasking trait unexpected
Tagcloud (Intersection) ?