GNL3 and CEP19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (proximity labelling technology, two hybrid)

		GNL3	CEP19
Description		G protein nucleolar 3	centrosomal protein 19
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Chromosome Nucleolus Membrane Nuclear Body Midbody	Spindle Pole Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Ciliary Basal Body Cell Projection
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding GTP Binding MRNA 5'-UTR Binding	Protein Binding
	Biological Process	Stem Cell Division Stem Cell Population Maintenance Positive Regulation Of Telomere Maintenance Positive Regulation Of Protein Sumoylation Regulation Of Cell Population Proliferation Positive Regulation Of MiRNA Transcription Positive Regulation Of Protein Localization To Chromosome, Telomeric Region	Cell Projection Organization Microtubule Anchoring At Centrosome Cilium Assembly Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Adiponectin levels ( 22479202) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Bipolar disorder ( 21926972 31043756) Bipolar disorder with mood-incongruent psychosis ( 23092984) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Intelligence (MTAG) ( 29326435) Iron status biomarkers (ferritin levels) ( 33536631) Osteoarthritis ( 22763110) Schizophrenia ( 29483656 28991256 25056061 23974872) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 30929738 31959851)
Interacting Genes		14 interacting genes: ANXA1 ASCC2 CEP19 DYSF ING4 MDM2 NPM1 OGT PPP2R5A PTEN STAT3 TP53 USP7 WEE2-AS1	47 interacting genes: AK4 ANAPC15 CALCOCO1 CCDC102B CCDC106 CCDC74A CDR1 CREB3L2 CREB3L3 EVI5 FOXR1 GMEB2 GNL3 HSPB2 HSPB2-C11orf52 KIAA1958 KXD1 LYSMD2 NOTO PAPSS2 PEX13 PGCKA1 PIBF1 PICK1 PIK3R3 PLEKHO1 PRAP1 PRKAR1B PTPN23 RABL2B REL ROBO4 SENP3 SYNE4 TNNI1 TRAIP TSPYL2 TVP23B TXLNB VCP VPS52 ZBTB10 ZBTB14 ZFP1 ZNF420 ZNF438 ZNF81
Entrez ID		26354	84984
HPRD ID		06419	17488
Ensembl ID		ENSG00000163938	ENSG00000174007
Uniprot IDs		Q9BVP2	A8MX07 Q96LK0
PDB IDs		8FKP 8FKR 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL0 8FL2 8FL3 8FL4 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8RL2
Enriched GO Terms of Interacting Partners?		Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle Phase Transition Cellular Response To Actinomycin D Regulation Of Cellular Component Organization Regulation Of G1/S Transition Of Mitotic Cell Cycle Organelle Organization Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cell Cycle Regulation Of Protein Stability Response To Actinomycin D Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Negative Regulation Of Proteolysis Protein Localization To Nucleus Cellular Response To UV-C Negative Regulation Of Protein Metabolic Process Negative Regulation Of Phosphate Metabolic Process Negative Regulation Of Cellular Component Organization Negative Regulation Of MiRNA Processing Negative Regulation Of Gene Expression Regulation Of Cell Cycle Process Regulation Of Carbohydrate Catabolic Process Protein-containing Complex P53 Binding Cellular Response To Antibiotic DNA Alkylation Repair Cellular Component Assembly Protein Stabilization Regulation Of Purine Nucleotide Metabolic Process Nucleoplasm Cellular Response To UV Cellular Response To Nutrient Levels Rhythmic Process Response To UV-C Regulation Of MiRNA Processing Regulation Of Cellular Response To Stress Regulation Of Vesicle-mediated Transport Negative Regulation Of MiRNA-mediated Gene Silencing Regulation Of Regulatory NcRNA Processing Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Regulation Of Glucose Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Autophagy Cellular Response To Light Stimulus Core Promoter Sequence-specific DNA Binding PML Body Regulation Of Cell Communication
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