GNL3 and ING4

Number of citations of the paper that reports this interaction (PubMedID 31754246)
68

Data Source:
BioGRID (affinity chromatography technology, pull down)

		GNL3	ING4
Description		G protein nucleolar 3	inhibitor of growth family member 4
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Chromosome Nucleolus Membrane Nuclear Body Midbody	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytosol Intermediate Filament Cytoskeleton
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding GTP Binding MRNA 5'-UTR Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Histone H3K14 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Metal Ion Binding Histone H4K16 Acetyltransferase Activity Histone H3K4me3 Reader Activity
	Biological Process	Stem Cell Division Stem Cell Population Maintenance Positive Regulation Of Telomere Maintenance Positive Regulation Of Protein Sumoylation Regulation Of Cell Population Proliferation Positive Regulation Of MiRNA Transcription Positive Regulation Of Protein Localization To Chromosome, Telomeric Region	Regulation Of Cell Growth Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Protein Acetylation Apoptotic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Negative Regulation Of Growth Regulation Of Cell Cycle DNA Replication-dependent Chromatin Disassembly Regulation Of Cell Cycle G2/M Phase Transition Regulation Of DNA Biosynthetic Process
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	HATs acetylate histones
Drugs
Diseases
GWAS		Adiponectin levels ( 22479202) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Bipolar disorder ( 21926972 31043756) Bipolar disorder with mood-incongruent psychosis ( 23092984) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Intelligence (MTAG) ( 29326435) Iron status biomarkers (ferritin levels) ( 33536631) Osteoarthritis ( 22763110) Schizophrenia ( 29483656 28991256 25056061 23974872) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		14 interacting genes: ANXA1 ASCC2 CEP19 DYSF ING4 MDM2 NPM1 OGT PPP2R5A PTEN STAT3 TP53 USP7 WEE2-AS1	23 interacting genes: BEX3 CDC34 EGLN1 EP300 GNL3 GRIPAP1 H3-4 H3C1 HNRNPD HOXB9 JADE2 KAT7 MAPK8IP2 MSX1 MYC NAV2 NOLC1 RELA SUV39H1 TLX3 TP53 TRIM55 TRIM63
Entrez ID		26354	51147
HPRD ID		06419	09774
Ensembl ID		ENSG00000163938	ENSG00000111653
Uniprot IDs		Q9BVP2	Q9UNL4
PDB IDs		8FKP 8FKR 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL0 8FL2 8FL3 8FL4 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8RL2	2K1J 2M1R 2PNX 2VNF 4AFL
Enriched GO Terms of Interacting Partners?		Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle Phase Transition Cellular Response To Actinomycin D Regulation Of Cellular Component Organization Regulation Of G1/S Transition Of Mitotic Cell Cycle Organelle Organization Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cell Cycle Regulation Of Protein Stability Response To Actinomycin D Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Negative Regulation Of Proteolysis Protein Localization To Nucleus Cellular Response To UV-C Negative Regulation Of Protein Metabolic Process Negative Regulation Of Phosphate Metabolic Process Negative Regulation Of Cellular Component Organization Negative Regulation Of MiRNA Processing Negative Regulation Of Gene Expression Regulation Of Cell Cycle Process Regulation Of Carbohydrate Catabolic Process Protein-containing Complex P53 Binding Cellular Response To Antibiotic DNA Alkylation Repair Cellular Component Assembly Protein Stabilization Regulation Of Purine Nucleotide Metabolic Process Nucleoplasm Cellular Response To UV Cellular Response To Nutrient Levels Rhythmic Process Response To UV-C Regulation Of MiRNA Processing Regulation Of Cellular Response To Stress Regulation Of Vesicle-mediated Transport Negative Regulation Of MiRNA-mediated Gene Silencing Regulation Of Regulatory NcRNA Processing Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Regulation Of Glucose Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Autophagy Cellular Response To Light Stimulus Core Promoter Sequence-specific DNA Binding PML Body Regulation Of Cell Communication	Nucleoplasm Nucleus Regulation Of Cellular Response To Stress Chromatin Organization Positive Regulation Of MiRNA Transcription Chromatin Remodeling Epigenetic Regulation Of Gene Expression Positive Regulation Of MiRNA Metabolic Process Regulation Of DNA Metabolic Process Regulation Of MiRNA Transcription Histone Acetyltransferase Complex Regulation Of DNA Biosynthetic Process Regulation Of MiRNA Metabolic Process Chromatin Negative Regulation Of Catabolic Process Response To Actinomycin D Regulation Of Telomere Maintenance Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Transcription By RNA Polymerase II Chromosome Nucleic Acid Metabolic Process Positive Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Response To Hypoxia Transcription Initiation-coupled Chromatin Remodeling Circadian Rhythm Chromatin Binding Transcription Coactivator Binding Positive Regulation Of DNA-templated Transcription Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Response To Nicotine Cellular Response To Decreased Oxygen Levels Cellular Response To Hypoxia Histone H4K16 Acetyltransferase Activity Positive Regulation Of Gene Expression, Epigenetic Response To UV Response To Decreased Oxygen Levels RNA Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Response To Oxygen Levels Canonical NF-kappaB Signal Transduction Anterior/posterior Pattern Specification Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?