FXR1 and MYH10

Number of citations of the paper that reports this interaction (PubMedID 21653829)
54

Data Source:
BioGRID (two hybrid)

		FXR1	MYH10
Description		FMR1 autosomal homolog 1	myosin heavy chain 10
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleolus Cytoplasm Cytosol Ribosome Cytoplasmic Stress Granule Membrane Axon Dendrite Ribonucleoprotein Granule Cytoplasmic Ribonucleoprotein Granule Cell Projection Neuron Projection Costamere Dendritic Spine Intracellular Membraneless Organelle Synapse Perinuclear Region Of Cytoplasm Presynapse Postsynapse Glutamatergic Synapse	Stress Fiber Nucleus Cytoplasm Spindle Cytosol Plasma Membrane Brush Border Cell Cortex Cytoplasmic Side Of Plasma Membrane Cell Surface Membrane Myosin Complex Myosin II Complex Sarcoplasm Lamellipodium Axon Growth Cone Midbody Neuromuscular Junction Cleavage Furrow Myosin Filament Actomyosin Cell Projection Neuron Projection Neuronal Cell Body Dendritic Spine Extracellular Exosome Myosin II Filament Postsynaptic Actin Cytoskeleton Glutamatergic Synapse Supramolecular Fiber
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding RNA Strand Annealing Activity MRNA 3'-UTR AU-rich Region Binding Protein Homodimerization Activity Ribonucleoprotein Complex Binding Translation Regulator Activity Protein Heterodimerization Activity Molecular Condensate Scaffold Activity	Microfilament Motor Activity Nucleotide Binding Virus Receptor Activity Cytoskeletal Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding RNA Stem-loop Binding ADP Binding MRNA 5'-UTR Binding Actin Filament Binding
	Biological Process	Cytoplasmic Translational Initiation Regulation Of Translation Apoptotic Process Spermatogenesis Spermatid Development Muscle Organ Development Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Translation Dentate Gyrus Development Cell Differentiation Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Rho Protein Signal Transduction Regulation Of MRNA Stability Regulation Of Circadian Sleep/wake Cycle, Sleep Positive Regulation Of Translation Positive Regulation Of Long-term Neuronal Synaptic Plasticity Animal Organ Development Negative Regulation Of Inflammatory Response Regulation Of Neurogenesis MRNA Transport Nuclear Pore Complex Assembly Nuclear Pore Localization Regulation Of Synaptic Transmission, Glutamatergic Skeletal Muscle Organ Development Muscle Structure Development MRNA Destabilization Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Membraneless Organelle Assembly Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of MRNA Catabolic Process Positive Regulation Of MiRNA-mediated Gene Silencing	Mitotic Cytokinesis In Utero Embryonic Development Neuron Migration Plasma Membrane Repair Cardiac Septum Development Exocytosis Substrate-dependent Cell Migration, Cell Extension Nuclear Migration Cell Adhesion Axonogenesis Axon Guidance Brain Development Heart Development Adult Heart Development Regulation Of Cell Shape Fourth Ventricle Development Lateral Ventricle Development Third Ventricle Development Cerebellar Purkinje Cell Layer Development Actin Cytoskeleton Organization Actin Filament-based Movement Myofibril Assembly Actomyosin Structure Organization Neuron Projection Development Aorta Development Symbiont Entry Into Host Cell Positive Regulation Of Protein Secretion Neuromuscular Process Controlling Balance Cardiac Myofibril Assembly Ventricular Cardiac Muscle Cell Development Cardiac Muscle Cell Proliferation Retina Development In Camera-type Eye Coronary Vasculature Development Postsynaptic Actin Cytoskeleton Organization
Pathways		Signaling by BRAF and RAF1 fusions	EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Bipolar disorder and eating disorder ( 26433762) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eating disorder in bipolar disorder ( 26433762) Mastocytosis ( 32752121) Metabolite levels ( 23823483) Schizophrenia ( 19571811 25056061 29483656 30285260)	Type 2 diabetes ( 30130595)
Interacting Genes		254 interacting genes: ABI1 ACLY ACOT7 ACTB ACTN1 ACTN2 ADAMTSL4 AHCY ALAS1 ANKRD40 ANKS3 AP1M1 APC2 ARHGAP22 ARHGEF7 ATN1 AXIN1 AXIN2 BCKDK BEND5 BHLHE40 BICD1 BLK BLTP3B BTBD2 BTBD6 BYSL C1orf35 CA10 CACTIN-AS1 CALCOCO1 CAMK2A CAMK2B CAMK2G CAPN3 CBS CBX8 CCAR2 CCBE1 CCDC187 CCDC92 CCN3 CDC7 CDKL3 CDR2 CDYL CEP126 CEP72 CEP89 CHRD CIRSR COIL CORO1A CORO1B CORO6 CPLANE1 CRMP1 CSNK2A1 CSNK2B CWF19L2 CYFIP2 DCTD DCTN1 DCTN2 DCTPP1 DEAF1 DHX15 DNAJA3 DNM2 ECH1 ECHS1 ECM1 EDC4 EFEMP2 EGFL7 EIF3A ELOA ENO1 ERCC6 ERG28 ERVFRD-1 ESCO2 EVL FAM161A FAM90A1 FBLN1 FLAD1 FLNB FMR1 FTH1 FXR2 GBP2 GFAP GLYR1 GOLGA2 GOLGA3 GPSM2 GRIA2 GRIP1 GRIP2 GRIPAP1 HIVEP1 HLA-DRB5 HMG20A HNRNPH2 HNRNPM HNRNPUL1 HOMER2 HOMER3 HSPB1 IK IMPDH2 INA JAKMIP1 KAZN KCNN1 KCTD1 KCTD13 KEAP1 KHDRBS1 KHDRBS3 KIAA1549L KIF17 KIF9 KRT18 LAP3 LNX1 LRIF1 LRSAM1 LUC7L2 LZTS2 MAD1L1 MAGED1 MAGOH MAGOHB MAPK7 MAPK8IP3 MAPKBP1 MBIP MCRS1 MFAP1 MLLT1 MOAP1 MSANTD3 MTUS2 MVP MX1 MYH10 MYH9 MYO5B N4BP3 NBPF15 NECAB2 NECAB3 NEFL NEIL3 NKD2 NME1 NME1-NME2 NME3 PAFAH1B3 PAICS PCCB PCED1A PDE9A PHC1P1 PHC2 PHLDB1 PKM PML PNMA1 PPHLN1 PPP1R12C PRAM1 PRKCSH PRPF31 PRR13 PRSS23 PSMC3 PSMC5 PSME1 PSME3 PYCR1 PYCR2 PYCR3 RABAC1 RALYL RBM26 RBM45 RPIA RUSC2 SAFB2 SAMD1 SCMH1 SEPTIN2 SERTAD1 SF3B2 SFPQ SH3GL2 SH3GLB2 SHANK1 SHARPIN SLC48A1 SLIT1 SMN1 SNURF SORBS3 SOX5 SPECC1 SPRY1 SPRY2 SRPK2 SSNA1 STK16 STUB1 SUFU SYT6 TACC2 TASOR2 TBC1D22B TCEA2 TDRD7 TLE5 TMPO TNFAIP1 TRAF2 TRAP1 TRIM3 TRIOBP TRPM1 TSN TTLL5 TUBB UBAP2L UBP1 USP7 UXS1 VIM VPS51 VWF WASH6P WEE2-AS1 WRNIP1 YAP1 YES1 YY1AP1 ZFTRAF1 ZMAT2 ZNF212 ZNF417 ZNF423 ZNF438 ZNF71 ZNF821	14 interacting genes: ANXA1 APC BCAP31 DUX4 ECPAS FXR1 FXR2 MYH9 PBX1 PTEN S100A4 YWHAE YWHAG ZNF512B
Entrez ID		8087	4628
HPRD ID		02892	01178
Ensembl ID		ENSG00000114416	ENSG00000133026
Uniprot IDs		E7EU85 P51114	A0A8I5KZ38 G1UI33 P35580
PDB IDs		2CPQ 3KUF 3O8V	4PD3
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Cytosol Cytoplasm Cytoskeleton Protein Binding Regulation Of Proteolysis Cytoskeleton Organization Postsynaptic Cytoskeleton Organization Centrosome Nucleoplasm Protein Domain Specific Binding Regulation Of Proteasomal Protein Catabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Pyrroline-5-carboxylate Reductase Activity Nucleus Neuron Projection Actin Filament Organelle Organization Synapse Positive Regulation Of Proteolysis Mitotic Spindle Pole RNA Splicing, Via Transesterification Reactions Calcium- And Calmodulin-dependent Protein Kinase Complex Regulation Of Protein Metabolic Process L-proline Biosynthetic Process RNA Splicing PcG Protein Complex MRNA Processing Stress Fiber MRNA Splicing, Via Spliceosome Microtubule Cytoskeleton Organization Supramolecular Fiber Organization Nervous System Development Postsynaptic Actin Cytoskeleton Organization Protein Homodimerization Activity Regulation Of Ubiquitin-dependent Protein Catabolic Process DNA Protection Cell Cortex U2-type Precatalytic Spliceosome Bud Elongation Involved In Lung Branching Glutamate Receptor Signaling Pathway Structural Constituent Of Cytoskeleton Postsynaptic Density Microtubule Binding Crotonyl-CoA Hydratase Activity Uropod Organization Protein Kinase Binding RNA Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process GTP Biosynthetic Process	Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Protein Targeting Dentate Gyrus Development Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Cytosol Positive Regulation Of Protein Metabolic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Macromolecule Metabolic Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Primary Metabolic Process Lateral Plasma Membrane Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Cytoplasmic Stress Granule Protein Localization To Endoplasmic Reticulum Cytoplasm Translation Regulator Activity Regulation Of Macromolecule Biosynthetic Process RNA Binding Regulation Of Cell Differentiation Regulation Of Mitotic Cell Cycle Negative Regulation Of Protein Phosphorylation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Toll-like Receptor Signaling Pathway Meiotic Spindle Organization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Phosphorylation Positive Regulation Of Signal Transduction Plasma Membrane Bounded Cell Projection Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Catabolic Process Positive Regulation Of Transcription By RNA Polymerase II Mononuclear Cell Differentiation Regulation Of Wound Healing Regulation Of Mitotic Cell Cycle Phase Transition Molecular Function Inhibitor Activity Negative Regulation Of Metabolic Process Cytoplasmic Translational Initiation Positive Regulation Of Cell Communication Positive Regulation Of Signaling Microfilament Motor Activity Positive Regulation Of Translation Regulation Of G1/S Transition Of Mitotic Cell Cycle
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?