STAP1 and URI1

Number of citations of the paper that reports this interaction (PMID 14615539)
46

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		STAP1	URI1
Gene Name		signal transducing adaptor family member 1	URI1, prefoldin-like chaperone
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Protein Complex	Nucleus DNA-directed RNA Polymerase II, Core Complex Cytoplasm Mitochondrion Dendrite
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding	RNA Polymerase II Transcription Corepressor Activity Chromatin Binding Protein Phosphatase Inhibitor Activity Protein Binding Phosphatase Inhibitor Activity
	Biological Process	Intracellular Protein Transport Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Membrane Fusion	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Growth Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Response To Virus Negative Regulation Of Phosphatase Activity Cellular Response To Growth Factor Stimulus Cellular Response To Steroid Hormone Stimulus Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: FAM134C KIT PTK2B SH3KBP1 TEC URI1	9 interactors: APP ATF7 DMAP1 GTF2F2 ITCH NEDD4 POLR2E RPS6KB1 STAP1
Entrez ID		26228	8725
HPRD ID		16053	11943
Ensembl ID		ENSG00000035720	ENSG00000105176
Uniprot IDs		Q9ULZ2	O94763
PDB IDs		1X1F 3MAZ
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Shape Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Protein Autophosphorylation Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of Programmed Cell Death Response To Hormone Negative Regulation Of Cell Death Peptidyl-tyrosine Phosphorylation Peptidyl-tyrosine Autophosphorylation Locomotion Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Lipid Kinase Activity Cellular Response To Lipid Positive Regulation Of JAK-STAT Cascade Movement Of Cell Or Subcellular Component Regulation Of Cell Morphogenesis Regulation Of Cell Death Regulation Of JAK-STAT Cascade Cellular Response To Hormone Stimulus Epithelial Cell Migration Response To External Stimulus Epithelium Migration B Cell Differentiation Cellular Response To Organic Substance Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Mast Cell Proliferation Regulation Of Cellular Component Organization Response To Hydrogen Peroxide Integrin-mediated Signaling Pathway Innate Immune Response Regulation Of CGMP-mediated Signaling Marginal Zone B Cell Differentiation Positive Regulation Of B Cell Chemotaxis Kit Signaling Pathway Erythropoietin-mediated Signaling Pathway Leukocyte Activation Involved In Immune Response Cell Migration B Cell Activation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Response To Lipid Regulation Of Synaptic Plasticity Response To Organic Cyclic Compound Cell Motility Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Apoptotic Process	Viral Process Regulation Of Gene Expression Intracellular Receptor Signaling Pathway Regulation Of Growth 7-methylguanosine MRNA Capping Protein K63-linked Ubiquitination 7-methylguanosine RNA Capping Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Viral Transcription Neuromuscular Junction Development Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Transcription Elongation From RNA Polymerase II Promoter Regulation Of Viral Transcription Positive Regulation Of Viral Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Nitrogen Compound Metabolic Process MRNA Processing DNA-templated Transcription, Elongation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Response To Stress Regulation Of Synapse Structure Or Activity Regulation Of Metabolic Process Interaction With Host Regulation Of Type I Interferon Production Positive Regulation Of Protein Metabolic Process Positive Regulation Of Nucleocytoplasmic Transport Synaptic Growth At Neuromuscular Junction Positive Regulation Of Skeletal Muscle Tissue Growth Locomotion Positive Regulation Of Mitotic Cell Cycle MRNA Metabolic Process Immune Response Negative Regulation Of Gene Expression RNA Processing Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Collateral Sprouting In Absence Of Injury Notch Signaling Pathway Regulation Of Viral Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Regulation Of Signal Transduction Protein Polyubiquitination Skeletal Muscle Atrophy
Tagcloud ?		4p13 abbreviation adaptor adh apolipoprotein asp207asn associate convertase exome fh4 fourth glu97asp hypercholesterolemia ile71thr kexin leu69ser lipoprotein mapped missense nonaffected parametric probands proprotein relatives sanger subtilisin suffer thereafter transducing
Tagcloud (Difference) ?		4p13 abbreviation adaptor adh apolipoprotein asp207asn associate convertase exome fh4 fourth glu97asp hypercholesterolemia ile71thr kexin leu69ser lipoprotein mapped missense nonaffected parametric probands proprotein relatives sanger subtilisin suffer thereafter transducing
Tagcloud (Intersection) ?