STAP1

Gene Name		signal transducing adaptor family member 1
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Protein Complex
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding
	Biological Process	Intracellular Protein Transport Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Membrane Fusion
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: FAM134C KIT PTK2B SH3KBP1 TEC URI1
Entrez ID		26228
HPRD ID		16053
Ensembl ID		ENSG00000035720
Uniprot IDs		Q9ULZ2
PDB IDs		1X1F 3MAZ
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Shape Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Protein Autophosphorylation Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of Programmed Cell Death Response To Hormone Negative Regulation Of Cell Death Peptidyl-tyrosine Phosphorylation Peptidyl-tyrosine Autophosphorylation Locomotion Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Lipid Kinase Activity Cellular Response To Lipid Positive Regulation Of JAK-STAT Cascade Movement Of Cell Or Subcellular Component Regulation Of Cell Morphogenesis Regulation Of Cell Death Regulation Of JAK-STAT Cascade Cellular Response To Hormone Stimulus Epithelial Cell Migration Response To External Stimulus Epithelium Migration B Cell Differentiation Cellular Response To Organic Substance Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Mast Cell Proliferation Regulation Of Cellular Component Organization Response To Hydrogen Peroxide Integrin-mediated Signaling Pathway Innate Immune Response Regulation Of CGMP-mediated Signaling Marginal Zone B Cell Differentiation Positive Regulation Of B Cell Chemotaxis Kit Signaling Pathway Erythropoietin-mediated Signaling Pathway Leukocyte Activation Involved In Immune Response Cell Migration B Cell Activation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Response To Lipid Regulation Of Synaptic Plasticity Response To Organic Cyclic Compound Cell Motility Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Apoptotic Process
Tagcloud ?		4p13 abbreviation adaptor adh apolipoprotein asp207asn associate convertase exome fh4 fourth glu97asp hypercholesterolemia ile71thr kexin leu69ser lipoprotein mapped missense nonaffected parametric probands proprotein relatives sanger subtilisin suffer thereafter transducing