SS18L1 and FAM168A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		SS18L1	FAM168A
Description		SS18L1 subunit of BAF chromatin remodeling complex	family with sequence similarity 168 member A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome Cytosol NBAF Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding	Protein Binding
	Biological Process	Chromatin Organization Dendrite Development Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Dendrite Morphogenesis	Positive Regulation Of Base-excision Repair
Pathways		Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of the non-canonical BAF (ncBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514)	Apolipoprotein A1 levels ( 32203549) Diastolic blood pressure ( 30224653) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 30061609) Platelet count ( 32888494) Pulmonary function (smoking interaction) ( 23284291) Refractive error ( 32231278) Waist-hip ratio ( 28552196)
Interacting Genes		43 interacting genes: AATF ANKRD22 ATF3 ATN1 BAG4 BICRAL BRD1 C1orf94 CEP55 CREBBP CSTF2 DGCR6 ELF5 EP300 FAM168A GATAD1 HDAC2 HDAC4 HGS LGALS3 MAPK1IP1L MED30 MIA2 NAF1 NR1H3 PAX8 PCGF6 RFX6 RLIM SF3B4 SMAD1 SMAD3 SMARCA4 SNRPB SNRPC SSBP3 STAT3 TAF9B TCF7 TNK1 USP54 ZMIZ2 ZMYND19	77 interacting genes: AKT1 ALKBH4 ATXN1 ATXN1L BOLL C10orf55 C1orf94 CALCOCO2 CAMK2A DAB1 DAZAP2 DCUN1D1 DTX2 EPN2 EPN3 FAM168B FBXW5 HGS HIP1 HR KLHL42 KRTAP19-1 KRTAP19-5 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP6-2 KRTAP7-1 KRTAP8-1 LASP1 MEIS2 NAF1 NFYC OTUB2 OTULIN PATZ1 PEF1 PITX1 PLEKHB2 PROP1 PRR20A PRR20B PRR20C PRR20D PRR20E PSORS1C1 R3HDM2 RBFOX1 RBPMS RBPMS2 RHOXF2 RNF216 RPS27A SECISBP2 SF1 SMAP2 SNRPC SS18L1 TAX1BP1 TFAP2D TFG TIAL1 TNIP1 TNK1 TOLLIP UBA52 UBAC1 UBASH3B UBB UBC UBE2V1 UBQLN2 UBXN6 UBXN7 VPS37C YOD1 YTHDF1
Entrez ID		26039	23201
HPRD ID		09398	13792
Ensembl ID		ENSG00000184402	ENSG00000054965
Uniprot IDs		B4DSR7 O75177	Q92567
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Nucleoplasm Transcription Cis-regulatory Region Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Transcription Regulator Complex Chromatin DNA Binding Chromatin Remodeling Positive Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression DNA-binding Transcription Factor Binding Histone H3K27 Acetyltransferase Activity Transcription Coactivator Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of MiRNA Transcription Regulation Of Metabolic Process Negative Regulation Of Developmental Process Regulation Of Cell Differentiation Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Sterol Response Element Binding Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Metabolic Process Chromatin Organization SMAD Protein Signal Transduction Regulation Of Stem Cell Population Maintenance Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Regulation Of MiRNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Protein Tag Activity Intermediate Filament Post-translational Protein Modification Ubiquitin Protein Ligase Binding Protein Binding Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Ubiquitination Cytoplasmic Stress Granule Modification-dependent Protein Catabolic Process Endocytic Vesicle Membrane Positive Regulation Of Post-translational Protein Modification Macromolecule Catabolic Process Autophagy Proteolysis Regulation Of Post-translational Protein Modification POZ Domain Binding Cytosol Positive Regulation Of Protein Monoubiquitination Identical Protein Binding Protein Modification Process Regulation Of Protein Monoubiquitination Glutamate Receptor Binding Clathrin-coated Vesicle Ubiquitin Conjugating Enzyme Binding RNA Stabilization Clathrin Binding Clathrin Vesicle Coat Regulation Of MRNA Metabolic Process Protein Metabolic Process Catabolic Process Endosome Transport Via Multivesicular Body Sorting Pathway Macroautophagy Negative Regulation Of RNA Catabolic Process Cytoplasm Positive Regulation Of Macromolecule Metabolic Process MRNA Binding Protein K11-linked Deubiquitination RNA Binding Vesicle Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Positive Regulation Of Translational Initiation Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Multivesicular Body Sorting Pathway Ubiquitin Binding Proteasomal Protein Catabolic Process
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