SS18L1 and MIA2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SS18L1	MIA2
Description		SS18L1 subunit of BAF chromatin remodeling complex	MIA SH3 domain ER export factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome Cytosol NBAF Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Exit Site
	Molecular Function	Transcription Coactivator Activity Protein Binding	Protein Binding Enzyme Activator Activity Cargo Receptor Activity
	Biological Process	Chromatin Organization Dendrite Development Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Dendrite Morphogenesis	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Secretion Protein Exit From Endoplasmic Reticulum Vesicle Cargo Loading Lipoprotein Transport Protein Localization To Endoplasmic Reticulum Exit Site
Pathways		Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of the non-canonical BAF (ncBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)	Cargo concentration in the ER
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514)
Interacting Genes		43 interacting genes: AATF ANKRD22 ATF3 ATN1 BAG4 BICRAL BRD1 C1orf94 CEP55 CREBBP CSTF2 DGCR6 ELF5 EP300 FAM168A GATAD1 HDAC2 HDAC4 HGS LGALS3 MAPK1IP1L MED30 MIA2 NAF1 NR1H3 PAX8 PCGF6 RFX6 RLIM SF3B4 SMAD1 SMAD3 SMARCA4 SNRPB SNRPC SSBP3 STAT3 TAF9B TCF7 TNK1 USP54 ZMIZ2 ZMYND19	15 interacting genes: CCHCR1 CEP57 DGCR6 EMILIN1 GRB2 MAGEB18 PDCD6 PSMA3 RASAL2 RSPH1 SEC23A SEC24C SS18L1 TLE5 TTC23L
Entrez ID		26039	4253
HPRD ID		09398	03680
Ensembl ID		ENSG00000184402	ENSG00000150527
Uniprot IDs		B4DSR7 O75177	Q4G155 Q59FD2 Q96PC5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Nucleoplasm Transcription Cis-regulatory Region Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Transcription Regulator Complex Chromatin DNA Binding Chromatin Remodeling Positive Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression DNA-binding Transcription Factor Binding Histone H3K27 Acetyltransferase Activity Transcription Coactivator Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of MiRNA Transcription Regulation Of Metabolic Process Negative Regulation Of Developmental Process Regulation Of Cell Differentiation Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Sterol Response Element Binding Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Metabolic Process Chromatin Organization SMAD Protein Signal Transduction Regulation Of Stem Cell Population Maintenance Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Regulation Of MiRNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	COPII Vesicle Coat Endoplasmic Reticulum Exit Site ER To Golgi Transport Vesicle Membrane Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway COPII-coated Vesicle Cargo Loading Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Cargo Loading Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Developmental Process
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