SS18L1 and NAF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SS18L1	NAF1
Description		SS18L1 subunit of BAF chromatin remodeling complex	nuclear assembly factor 1 ribonucleoprotein
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome Cytosol NBAF Complex	Nucleus Nucleoplasm Sno(s)RNA-containing Ribonucleoprotein Complex Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding	RNA Binding Protein Binding Identical Protein Binding Telomerase RNA Binding
	Biological Process	Chromatin Organization Dendrite Development Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Dendrite Morphogenesis	SnoRNA Guided RRNA Pseudouridine Synthesis Box H/ACA SnoRNP Assembly Pseudouridine Synthesis RRNA Processing Protein-RNA Complex Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Ribosome Biogenesis RNA Stabilization Telomerase RNA Stabilization Telomerase RNA Localization To Cajal Body Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Telomerase Holoenzyme Complex Assembly
Pathways		Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of the non-canonical BAF (ncBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514)	Chronotype ( 30696823) Colorectal cancer ( 25023989) Daytime nap ( 33568662) Hair morphology ( 19896111) Leukocyte telomere length ( 31171785 32109421) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) TPE interval (recovery after exercise) ( 32386560)
Interacting Genes		43 interacting genes: AATF ANKRD22 ATF3 ATN1 BAG4 BICRAL BRD1 C1orf94 CEP55 CREBBP CSTF2 DGCR6 ELF5 EP300 FAM168A GATAD1 HDAC2 HDAC4 HGS LGALS3 MAPK1IP1L MED30 MIA2 NAF1 NR1H3 PAX8 PCGF6 RFX6 RLIM SF3B4 SMAD1 SMAD3 SMARCA4 SNRPB SNRPC SSBP3 STAT3 TAF9B TCF7 TNK1 USP54 ZMIZ2 ZMYND19	26 interacting genes: BOLL CSNK2A1 DAB1 ELOA FAM168A HERPUD2 KRTAP19-3 KRTAP19-7 KRTAP6-1 KRTAP6-2 MAGED1 MED31 MSX2 RAMAC RBFOX2 SCARNA13 SCARNA8 SH3RF1 SNORA74A SNX33 SORBS3 SS18L1 TENT5B TLE5 UBE2I YWHAE
Entrez ID		26039	92345
HPRD ID		09398	10054
Ensembl ID		ENSG00000184402	ENSG00000145414
Uniprot IDs		B4DSR7 O75177	Q96HR8
PDB IDs			2EQN
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Nucleoplasm Transcription Cis-regulatory Region Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Transcription Regulator Complex Chromatin DNA Binding Chromatin Remodeling Positive Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression DNA-binding Transcription Factor Binding Histone H3K27 Acetyltransferase Activity Transcription Coactivator Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of MiRNA Transcription Regulation Of Metabolic Process Negative Regulation Of Developmental Process Regulation Of Cell Differentiation Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Sterol Response Element Binding Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Metabolic Process Chromatin Organization SMAD Protein Signal Transduction Regulation Of Stem Cell Population Maintenance Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Regulation Of MiRNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
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