SUGT1

Description		SGT1 assembly cochaperone of MIS12 kinetochore complex
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Kinetochore Nucleus Cytoplasm Cytosol Nuclear Body Protein-containing Complex
	Molecular Function	Protein Binding Protein-folding Chaperone Binding LncRNA Binding
	Biological Process	Spindle Organization Skeletal Muscle Satellite Cell Proliferation Regulation Of Protein Stability Kinetochore Assembly
Pathways		The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: HTR2A
Interacting Genes		18 interacting genes: BUB3 CEBPA CSNK2A1 DSN1 FNDC3B HSP90AA1 HSPA4 MIS12 NR4A1 NSL1 PAXIP1 PLK1 PMF1 PTGER4 S100A6 S100B S100P SKP1
Entrez ID		10910
HPRD ID		09160
Ensembl ID		ENSG00000165416
Uniprot IDs		A8K7W3 B4DYC6 Q9Y2Z0
PDB IDs		1RL1
Enriched GO Terms of Interacting Partners?		MIS12/MIND Type Complex Outer Kinetochore Attachment Of Spindle Microtubules To Kinetochore Chromosome Segregation Chromosome, Centromeric Region Kinetochore Spindle Pole Protein Localization To Organelle Chromosome Cell Division Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Nuclear Chromosome Segregation Nucleus Negative Regulation Of Cell Cycle Identical Protein Binding Positive Regulation Of Protein Catabolic Process Regulation Of Chromosome Separation Calcium-dependent Protein Binding Endothelial Cell Migration S100 Protein Binding Regulation Of DNA Metabolic Process Nucleoplasm Protein Localization To Chromosome Positive Regulation Of Catabolic Process Chaperone-mediated Protein Complex Assembly Memory Protein Import Into Mitochondrial Matrix Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Hormone Regulation Of DNA Recombination Regulation Of Chromosome Segregation PcG Protein Complex Establishment Of Protein Localization To Organelle Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Protein Localization To Site Of Double-strand Break Chromosome Organization Mitotic Spindle Assembly Checkpoint Signaling Regulation Of Apoptotic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Protein Catabolic Process Regulation Of Programmed Cell Death ATP-dependent Protein Folding Chaperone Regulation Of Cell Cycle Protein Homodimerization Activity Positive Regulation Of Inflammatory Response Protein Localization To Mitochondrion Negative Regulation Of Mitotic Nuclear Division Regulation Of Ubiquitin-dependent Protein Catabolic Process
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