SUGT1 and PMF1

Number of citations of the paper that reports this interaction (PMID 20404110)
16

Data Source:
BioGRID (pull down, affinity chromatography technology)

		SUGT1	PMF1
Gene Name		SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	polyamine-modulated factor 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Kinetochore Nucleus Cytoplasm Cytosol	MIS12/MIND Type Complex Nucleus Transcription Factor Complex Cytosol
	Molecular Function	Protein Binding	Transcription Coactivator Activity Protein Binding Leucine Zipper Domain Binding
	Biological Process	Mitotic Nuclear Division Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Innate Immune Response	Mitotic Cell Cycle Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Chromosome Segregation Mitotic Nuclear Division Cell Division
Pathways		The NLRP3 inflammasome Inflammasomes Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways Innate Immune System	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: BUB3 CSNK2A1 DSN1 HSP90AA1 HSPA4 MIS12 NR4A1 NSL1 PAXIP1 PLK1 PMF1 S100A6 S100B S100P SKP1	17 interactors: COPS6 COPS7A COPS7B CRMP1 DSN1 GDF9 GIT1 HSP90AA1 KDM1A KIAA1377 MED31 MIS12 NFE2L2 PTN SUGT1 TCP10L USHBP1
Entrez ID		10910	11243
HPRD ID		09160	11441
Ensembl ID			ENSG00000160783
Uniprot IDs		F5H5A9 Q9Y2Z0	D3DVB3 Q6P1K2
PDB IDs		1RL1
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Cycle Process Chromosome Segregation Cell Cycle Mitotic Nuclear Division Cell Division Mitotic Spindle Checkpoint Protein Import Into Mitochondrial Outer Membrane Negative Regulation Of Chromosome Segregation Organelle Organization Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Protein Ubiquitination Regulation Of Chromosome Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Endothelial Cell Migration Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Chromosome Organization Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Chaperone-mediated Protein Complex Assembly Epithelial Cell Migration Epithelium Migration Regulation Of Proteolysis Negative Regulation Of Protein Catabolic Process G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Proteolysis Regulation Of Mitotic Nuclear Division Negative Regulation Of Protein Processing Positive Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Processing Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Ameboidal-type Cell Migration Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Regulation Of Proteasomal Protein Catabolic Process Axonogenesis Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition	Cullin Deneddylation Protein Deneddylation Mitotic Cell Cycle Process Protein Modification By Small Protein Removal Mitotic Cell Cycle Cell Cycle Process Regulation Of Primitive Erythrocyte Differentiation Mitotic Nuclear Division Oocyte Growth Cell Cycle Positive Regulation Of Reactive Oxygen Species Metabolic Process Cell Projection Morphogenesis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Axon Guidance Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Embryonic Development Protein Import Into Mitochondrial Outer Membrane Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Regulation Of Progesterone Secretion Proteasomal Ubiquitin-independent Protein Catabolic Process Response To Unfolded Protein
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