SUGT1 and MIS12

Number of citations of the paper that reports this interaction (PMID 20404110)
16

Data Source:
BioGRID (pull down, affinity chromatography technology)

		SUGT1	MIS12
Gene Name		SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	MIS12 kinetochore complex component
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Kinetochore Nucleus Cytoplasm Cytosol	MIS12/MIND Type Complex Nucleus Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Nuclear Division Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Innate Immune Response	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Cell Division Kinetochore Assembly
Pathways		The NLRP3 inflammasome Inflammasomes Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways Innate Immune System	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: BUB3 CSNK2A1 DSN1 HSP90AA1 HSPA4 MIS12 NR4A1 NSL1 PAXIP1 PLK1 PMF1 S100A6 S100B S100P SKP1	10 interactors: CASC5 CBX3 CBX5 DSN1 HSP90AA1 NDC80 NSL1 PMF1 SUGT1 ZWINT
Entrez ID		10910	79003
HPRD ID		09160	12379
Ensembl ID			ENSG00000167842
Uniprot IDs		F5H5A9 Q9Y2Z0	A8K1M4 Q9H081
PDB IDs		1RL1
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Cycle Process Chromosome Segregation Cell Cycle Mitotic Nuclear Division Cell Division Mitotic Spindle Checkpoint Protein Import Into Mitochondrial Outer Membrane Negative Regulation Of Chromosome Segregation Organelle Organization Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Protein Ubiquitination Regulation Of Chromosome Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Endothelial Cell Migration Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Chromosome Organization Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Chaperone-mediated Protein Complex Assembly Epithelial Cell Migration Epithelium Migration Regulation Of Proteolysis Negative Regulation Of Protein Catabolic Process G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Proteolysis Regulation Of Mitotic Nuclear Division Negative Regulation Of Protein Processing Positive Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Processing Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Ameboidal-type Cell Migration Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Regulation Of Proteasomal Protein Catabolic Process Axonogenesis Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition	Mitotic Nuclear Division Mitotic Cell Cycle Process Mitotic Cell Cycle Chromosome Segregation Cell Cycle Process Cell Cycle Cell Division Organelle Organization Attachment Of Spindle Microtubules To Kinetochore Chromosome Organization Microtubule Anchoring Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Maintenance Of Protein Location In Cell Protein Import Into Mitochondrial Outer Membrane Chromatin Modification Maintenance Of Protein Location Maintenance Of Location In Cell Attachment Of Mitotic Spindle Microtubules To Kinetochore Chromatin Remodeling Chromatin Organization Protein Localization To Kinetochore Cell Cycle Checkpoint Protein Localization To Chromosome, Centromeric Region Histone H4-K5 Acetylation Histone H4-K8 Acetylation Chaperone-mediated Protein Complex Assembly Histone H4-K16 Acetylation Acrosome Assembly
Tagcloud ?			assembled ccan cenh3 cenp centromere centromeres centromeric continues deposition egg entails exit immunoprecipitate interphase kinetochore kinetochores mitosis ndc80 orchestrate precedes propagation reconstituted segregation sixteen soon spite vertebrate w xenopus
Tagcloud (Difference) ?			assembled ccan cenh3 cenp centromere centromeres centromeric continues deposition egg entails exit immunoprecipitate interphase kinetochore kinetochores mitosis ndc80 orchestrate precedes propagation reconstituted segregation sixteen soon spite vertebrate w xenopus
Tagcloud (Intersection) ?