MYRIP and C1orf216

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MYRIP	C1orf216
Gene Name		myosin VIIA and Rab interacting protein	chromosome 1 open reading frame 216
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Photoreceptor Outer Segment Actin Cytoskeleton Transport Vesicle Dense Core Granule Melanosome Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Protein Binding Zinc Ion Binding Rab GTPase Binding Protein Kinase A Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of Insulin Secretion
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23007406) Information processing speed ( 21130836) Sleep duration ( 17903308)
Protein-Protein Interactions		3 interactors: C1orf216 MYO7A RAB27A	28 interactors: AES AMOT CCDC114 CCDC136 CCDC158 CDR2 CEP170P1 GGA1 KRT13 KRT15 KRT31 KRT38 KRT40 LINC00521 MED4 MTUS2 MYRIP NMI NRBF2 NUP62 PSMC6 RALBP1 TPM1 TPM3 TRAF1 TRIM54 USHBP1 ZDHHC17
Entrez ID		25924	127703
HPRD ID		14796	08798
Ensembl ID		ENSG00000170011	ENSG00000142686
Uniprot IDs		Q8NFW9	Q8TAB5
PDB IDs
Enriched GO Terms of Interacting Partners?		Pigment Granule Transport Cellular Pigmentation Pigmentation Establishment Of Vesicle Localization Vesicle Localization Positive Regulation Of Constitutive Secretory Pathway Complement-dependent Cytotoxicity Multivesicular Body Organization Cytotoxic T Cell Degranulation Establishment Of Organelle Localization Multivesicular Body Sorting Pathway Exosomal Secretion Organelle Localization Natural Killer Cell Degranulation Epithelial Cell Differentiation Equilibrioception T Cell Mediated Cytotoxicity Post-embryonic Organ Morphogenesis Auditory Receptor Cell Stereocilium Organization Auditory Receptor Cell Morphogenesis Phagolysosome Assembly Auditory Receptor Cell Development Intracellular Protein Transport Natural Killer Cell Activation Involved In Immune Response Inner Ear Receptor Stereocilium Organization Positive Regulation Of Regulated Secretory Pathway Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Epithelium Development Leukocyte Mediated Cytotoxicity T Cell Mediated Immunity Endosome Organization Melanosome Transport Auditory Receptor Cell Differentiation Establishment Of Melanosome Localization Melanocyte Differentiation Leukocyte Degranulation Melanosome Localization Hair Cell Differentiation Eye Photoreceptor Cell Development Regulation Of Regulated Secretory Pathway Cellular Protein Localization Inner Ear Receptor Cell Development Protein Transport Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Neuroepithelial Cell Differentiation Phagosome Maturation Vesicle-mediated Transport Establishment Of Protein Localization Photoreceptor Cell Development	Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Heart Rate By Epinephrine Actin Filament-based Movement Regulation Of Stress Fiber Assembly Cellular Response To Stimulus Regulation Of Signaling Establishment Of Cell Polarity Involved In Ameboidal Cell Migration
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