OBFC1

Gene Name		oligonucleotide/oligosaccharide-binding fold containing 1
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Gene Ontology Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Intracellular Membrane-bounded Organelle Intermediate Filament Cytoskeleton Stn1-Ten1 Complex
	Molecular Function	Single-stranded DNA Binding Protein Binding Single-stranded Telomeric DNA Binding
	Biological Process	Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Positive Regulation Of DNA Replication
Pathways
Drugs
Diseases
GWAS		Endothelial function traits ( 17903301) Interstitial lung disease ( 23583980) Telomere length ( 23535734 20421499 23001564) Uterine fibroids ( 21460842)
Protein-protein Interactions		6 interactors: APP LDLRAP1 MVP TPP1 TUBGCP4 ZDHHC17
Entrez ID		79991
HPRD ID		14872
Ensembl ID
Uniprot IDs		Q9H668
PDB IDs		4JOI 4JQF
Enriched GO Terms of Interacting Partners?		Regulation Of Binding Regulation Of Protein Tyrosine Kinase Activity Neuromuscular Process Controlling Balance Negative Regulation Of Establishment Of Blood-brain Barrier Positive Regulation Of Single-stranded Telomeric DNA Binding Cholesterol Metabolic Process Sterol Metabolic Process Neuromuscular Process Regulation Of Establishment Of Blood-brain Barrier Synaptic Growth At Neuromuscular Junction Regulation Of Protein Kinase Activity Regulation Of Protein Binding Regulation Of Kinase Activity Collateral Sprouting In Absence Of Injury Receptor-mediated Endocytosis Of Low-density Lipoprotein Particle Involved In Cholesterol Transport Intermembrane Transport Chemical Homeostasis Vitamin E Metabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Collateral Sprouting Axon Midline Choice Point Recognition Protection From Non-homologous End Joining At Telomere Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Axon Choice Point Recognition Positive Regulation Of Telomerase Activity Telomere Assembly Regulation Of Protein Phosphorylation Steroid Metabolic Process Transport Neuron Remodeling Positive Regulation Of Cholesterol Metabolic Process Intracellular Cholesterol Transport Intracellular Sterol Transport Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Lipid Metabolic Process Negative Regulation Of Cell Development Regulation Of Phosphorylation Negative Regulation Of Protein Autophosphorylation Alcohol Metabolic Process Peptide Catabolic Process Protein Metabolic Process Homeostatic Process Regulation Of Signaling Protein Transport Regulation Of Telomerase Activity Regulation Of Cellular Amino Acid Metabolic Process
Tagcloud ?		aa ac ages biology cardiovascular caucasian cc cvd disequilibrium enrolled estimate etiologic genotyped hr insight intervals leukocyte linkage ltl minor polymorphisms rs3772190 rs4387287 rs9419958 similarly snps telomere terc trend