NUTM1 and SH2D1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NUTM1	SH2D1B
Description		NUT midline carcinoma family member 1	SH2 domain containing 1B
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol
	Molecular Function	Protein Binding	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process		Adaptive Immune Response Leukocyte Activation Involved In Immune Response Immune System Process Positive Regulation Of Natural Killer Cell Mediated Immunity Innate Immune Response Positive Regulation Of Innate Immune Response
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS			Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969) Takayasu arteritis ( 25604533)
Interacting Genes		54 interacting genes: ALOX5 AQP1 ARHGEF6 AXIN1 CATSPERT CCDC116 CCDC185 CCHCR1 CDC20B CDK18 CHCHD3 ENKD1 FAM161A GADD45GIP1 GPANK1 HSPBAP1 IFIT2 KANK2 KANSL1 KPNA2 LHX8 LMO1 LMO2 LMO3 LRRC8E MBD3 METTL17 MORN4 MTCL2 NEBL OSTF1 P4HA3 PLEKHF2 PRKAA2 PRKAB2 PRPF18 PSME4 RCOR3 RIC8A SAMD4A SAMD4B SCNM1 SH2D1B SH2D4A SMARCD1 TBC1D21 TEAD4 TLE5 TP53BP2 TSGA10IP TTC23 TXN2 ZMYND10 ZNF277	25 interacting genes: AGR2 APP AR BLK CD244 CD84 EGFR ERBB2 ERBB3 ERBB4 GAB1 KIT LY9 MAGEB4 MAPK8IP2 MEOX2 MET NFKBID NUTM1 PRDX1 PTK2 SLAMF1 STAT4 TNK2 TRIM54
Entrez ID		256646	117157
HPRD ID		10606	12248
Ensembl ID		ENSG00000184507	ENSG00000198574
Uniprot IDs		A0AAG2UVG0 A0AAG2UVR5 A0AAG2UXE6 Q86Y26	O14796
PDB IDs		7XEZ 7XFG	5KAZ
Enriched GO Terms of Interacting Partners?		Protein Binding	Protein Tyrosine Kinase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Phosphate Metabolic Process Positive Regulation Of MAPK Cascade Receptor Complex Transmembrane Receptor Protein Tyrosine Kinase Activity Cell Surface Receptor Signaling Pathway Regulation Of MAPK Cascade Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Intracellular Signal Transduction Protein Kinase Activity ERBB2 Signaling Pathway Basal Plasma Membrane Leukocyte Activation Immune System Process Kinase Activity Defense Response Regulation Of Intracellular Signal Transduction Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Lymphocyte Activation Cell Activation Signal Transduction Cellular Developmental Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling External Side Of Plasma Membrane Developmental Process Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Regulation Of Phosphorus Metabolic Process Immune Effector Process Cell Differentiation Positive Regulation Of Phosphorylation ERBB3:ERBB2 Complex Regulation Of Multicellular Organismal Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Positive Regulation Of Biosynthetic Process Molecular Function Activator Activity Regulation Of Cell Migration Response To Stress
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