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H2BC1 and DNTTIP2
Number of citations of the paper that reports this interaction (PubMedID
12786946
)
0
Data Source:
BioGRID
(pull down)
H2BC1
DNTTIP2
Description
H2B clustered histone 1
deoxynucleotidyltransferase terminal interacting protein 2
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleosome
Female Germ Cell Nucleus
Nucleus
Nucleoplasm
Chromosome
Cell Surface
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Small-subunit Processome
Molecular Function
DNA Binding
Structural Constituent Of Chromatin
Histone Binding
Protein Heterodimerization Activity
RNA Binding
Protein Binding
Biological Process
Chromatin Organization
Nucleosome Assembly
Nucleosome Disassembly
Inflammatory Response
Plasminogen Activation
Sperm DNA Condensation
Chromosome Organization
Mononuclear Cell Migration
RNA Processing
Ribosomal Small Subunit Biogenesis
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
HDACs deacetylate histones
HATs acetylate histones
HATs acetylate histones
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Ub-specific processing proteases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
Deposition of new CENPA-containing nucleosomes at the centromere
Assembly of the ORC complex at the origin of replication
G2/M DNA damage checkpoint
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
E3 ubiquitin ligases ubiquitinate target proteins
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Inhibition of DNA recombination at telomere
Defective pyroptosis
Negative Regulation of CDH1 Gene Transcription
Amyloid fiber formation
Chromatin modifications during the maternal to zygotic transition (MZT)
Replacement of protamines by nucleosomes in the male pronucleus
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Regulation of endogenous retroelements by KRAB-ZFP proteins
Regulation of endogenous retroelements by KRAB-ZFP proteins
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS
Gut microbiota alpha diversity (PD_whole_tree index) (
33208821
)
Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome (
31991592
)
Interacting Genes
9 interacting genes:
ANP32B
APP
CCNA1
DNTTIP2
H2AC20
HDAC3
SET
UBE2B
USP44
18 interacting genes:
CAVIN1
CEP70
DNTT
ESR1
ESR2
H2AC25
H2BC1
H3C15
H4C16
PCNA
PICK1
PPARG
RBPMS
RNF10
RNF8
RXRA
SPP1
TULP3
Entrez ID
255626
30836
HPRD ID
11024
09994
Ensembl ID
ENSG00000146047
ENSG00000067334
Uniprot IDs
Q96A08
Q5QJE6
PDB IDs
3WKJ
5GSU
5GT3
6BIY
8VLR
7MQ8
7MQ9
7MQA
Enriched GO Terms of Interacting Partners
?
Chromatin Organization
Chromatin Remodeling
Amyloid-beta Complex
Growth Cone Lamellipodium
Regulation Of Neuron Apoptotic Process
Positive Regulation Of Establishment Of Protein Localization
Epigenetic Regulation Of Gene Expression
Regulation Of Response To Calcium Ion
Regulation Of Multicellular Organism Growth
Amylin Binding
Positive Regulation Of Toll Signaling Pathway
Regulation Of Apoptotic Process
Positive Regulation Of Cell Cycle
Regulation Of Programmed Cell Death
Nucleus
Positive Regulation Of Protein Transport
Regulation Of Post-translational Protein Modification
Regulation Of Protein Export From Nucleus
Positive Regulation Of Nucleocytoplasmic Transport
Positive Regulation Of Ferroptosis
Positive Regulation Of Neuron Apoptotic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Apoptotic Process
Acetylcholine Receptor Activator Activity
Negative Regulation Of Metabolic Process
Lipoprotein Particle
Positive Regulation Of Protein Import
Nucleoplasm
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Post-translational Protein Modification
Positive Regulation Of Reciprocal Meiotic Recombination
Protein De-2-hydroxyisobutyrylase Activity
Positive Regulation Of Intracellular Protein Transport
Cyclin A1-CDK1 Complex
Cyclin A1-CDK2 Complex
PTB Domain Binding
Collateral Sprouting In Absence Of Injury
Regulation Of Protein Import
Regulation Of Interleukin-1 Production
Endosome To Plasma Membrane Transport Vesicle
Positive Regulation Of Endothelin Production
Growth Cone Filopodium
Regulation Of Protein Transport
Chromatin Binding
Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Protein Localization
Microglia Development
Positive Regulation Of G Protein-coupled Receptor Internalization
Regulation Of Cell Cycle
Nucleosome Assembly
Nuclear Receptor Activity
DNA Binding
Enzyme Binding
Nuclear Steroid Receptor Activity
Structural Constituent Of Chromatin
Nuclear Receptor-mediated Signaling Pathway
Nuclear Estrogen Receptor Activity
DNA Binding Domain Binding
Nucleosome
Nucleosome Organization
Transcription Coregulator Binding
Positive Regulation Of Lipoprotein Transport
Nucleoplasm
Chromatin Organization
Hormone-mediated Signaling Pathway
LBD Domain Binding
Identical Protein Binding
Chromosome, Telomeric Region
Chromatin Remodeling
Protein-DNA Complex Assembly
Chromatin
Regulation Of DNA-templated Transcription
Estrogen Response Element Binding
Steroid Hormone Receptor Signaling Pathway
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Regulation Of RNA Biosynthetic Process
Peroxisome Proliferator Activated Receptor Signaling Pathway
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleus
Intracellular Receptor Signaling Pathway
Positive Regulation Of Lipid Transport
Chromatin Binding
Response To Lipid
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Protein Localization To Chromosome
Monocyte Differentiation
Sperm DNA Condensation
Nucleosome Disassembly
Nucleosome Assembly
Response To Estradiol
Negative Regulation Of RNA Biosynthetic Process
Protein-DNA Complex Disassembly
Estrogen Receptor Signaling Pathway
Retinoic Acid Receptor Signaling Pathway
Negative Regulation Of Transcription By RNA Polymerase II
Androgen Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of RNA Metabolic Process
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