HIST1H2BA

Gene Name		histone cluster 1, H2ba
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm Extrinsic Component Of Plasma Membrane
	Molecular Function	Molecular_function DNA Binding Protein Heterodimerization Activity
	Biological Process	Chromatin Organization Nucleosome Assembly Nucleosome Disassembly Inflammatory Response Plasminogen Activation Spermatogenesis, Exchange Of Chromosomal Proteins Positive Regulation Of Binding Mononuclear Cell Migration
Pathways		RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Mitotic Prophase Regulatory RNA pathways RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Cellular Senescence Signaling by Wnt HATs acetylate histones M Phase Amyloids NoRC negatively regulates rRNA expression Packaging Of Telomere Ends Telomere Maintenance Nucleosome assembly RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN DNA methylation Transcriptional regulation by small RNAs Meiotic recombination DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Chromatin organization HDACs deacetylate histones misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNA Polymerase I Transcription formation of the beta-catenin:TCF transactivating complex Meiotic synapsis Epigenetic regulation of gene expression Senescence-Associated Secretory Phenotype (SASP) Negative epigenetic regulation of rRNA expression PRC2 methylates histones and DNA Cell Cycle, Mitotic Chromatin modifying enzymes Oxidative Stress Induced Senescence TCF dependent signaling in response to WNT RNA Polymerase I Promoter Opening SIRT1 negatively regulates rRNA Expression Signaling by WNT in cancer Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: APP CCNA1 DNTTIP2 HIST2H2AC PARP1 SET
Entrez ID		255626
HPRD ID		11024
Ensembl ID		ENSG00000146047
Uniprot IDs		Q96A08
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Growth Rate Protein Poly-ADP-ribosylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of RNA Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Regulation Of Binding Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA Damage Response, Detection Of DNA Damage Positive Regulation Of Transcription Regulatory Region DNA Binding Neuron Remodeling Protein Autoprocessing Positive Regulation Of SMAD Protein Import Into Nucleus Nucleosome Disassembly Regulation Of Cellular Amino Acid Metabolic Process Regulation Of SMAD Protein Import Into Nucleus Regulation Of Mitotic Cell Cycle Response To Oxidative Stress Cellular Copper Ion Homeostasis Macrophage Differentiation Gene Expression Negative Regulation Of Histone Acetylation Cellular Response To Superoxide Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Copper Ion Homeostasis Suckling Behavior Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Cell Cycle Process Negative Regulation Of Protein Acetylation Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Superoxide Protein ADP-ribosylation Response To Oxygen Radical Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Transcription From RNA Polymerase II Promoter
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