KCTD13 and TNFAIP1

Number of citations of the paper that reports this interaction (PMID 19615732)
279

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		KCTD13	TNFAIP1
Gene Name		potassium channel tetramerization domain containing 13	tumor necrosis factor, alpha-induced protein 1 (endothelial)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cul3-RING Ubiquitin Ligase Complex	Nucleolus Cytoplasm Endosome Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity GTP-Rho Binding Protein Domain Specific Binding Identical Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding GTP-Rho Binding Protein Domain Specific Binding
	Biological Process	DNA Replication Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Protein Homooligomerization	DNA Replication Apoptotic Process Immune Response Embryo Development Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ADRB2 ARMC7 CUL3 KAT7 LNX1 NUDT18 PCNA POLD2 PPARG RHOA TNFAIP1 VTA1 ZMYND19	21 interactors: ARMC7 ARNT CAPN7 CARD9 CSNK2B CUL3 EPHA2 EPM2AIP1 EXOSC5 HAT1 KCTD13 KDM1A POLR1C PSMA1 RHOA RHOB RIN3 STK16 SUV39H1 SVIL ZDHHC17
Entrez ID		253980	7126
HPRD ID		12339	01856
Ensembl ID		ENSG00000174943	ENSG00000109079
Uniprot IDs		Q8WZ19	Q13829
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Replication Stress Fiber Assembly Regulation Of DNA Replication Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Semi-conservative Replication Nuclear DNA Replication Negative Regulation Of Rho Protein Signal Transduction Telomere Maintenance Via Recombination Protein Complex Assembly Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cytokinesis Transcription-coupled Nucleotide-excision Repair Brown Fat Cell Differentiation Mitotic Cell Cycle Response To Cold Regulation Of Cytokinesis Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Mismatch Repair Base-excision Repair Actin Filament Bundle Assembly Response To Metformin Low-density Lipoprotein Particle Receptor Biosynthetic Process DGDP Catabolic Process DADP Catabolic Process Negative Regulation Of Pancreatic Stellate Cell Proliferation Positive Regulation Of Deoxyribonuclease Activity Response To Diuretic GDP Catabolic Process Telomere Maintenance Nucleotide-excision Repair Chromosome Organization Cell Cycle Process Leading Strand Elongation Regulation Of Cholesterol Transporter Activity Cellular Response To Vitamin E Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Cellular Component Assembly DNA Metabolic Process DNA-dependent DNA Replication Negative Regulation Of Signal Transduction DNA Biosynthetic Process Actomyosin Structure Organization Ubiquitin-dependent Protein Catabolic Process Organelle Organization Modification-dependent Protein Catabolic Process Skeletal Muscle Satellite Cell Migration	Regulation Of Signal Transduction Regulation Of Signaling Response To Stimulus Regulation Of Intracellular Signal Transduction Positive Regulation Of Cytokinesis Regulation Of Cytokinesis Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cell Cycle Process Positive Regulation Of Hormone Biosynthetic Process Stress Fiber Assembly Positive Regulation Of Cell Cycle Cellular Protein Modification Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Division Response To Stress Negative Regulation Of Rho Protein Signal Transduction Regulation Of Cellular Process Regulation Of Hormone Biosynthetic Process Regulation Of Epithelial Cell Migration Cell Morphogenesis Involved In Differentiation Axon Guidance Negative Regulation Of Intracellular Signal Transduction Chromatin Silencing Regulation Of Hormone Metabolic Process Locomotion Regulation Of Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Erythrocyte Differentiation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To External Stimulus Cell Cycle Regulation Of Cell Cycle Process Regulation Of Gene Expression, Epigenetic Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Cycle Axonogenesis Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Primitive Erythrocyte Differentiation Notochord Cell Development Viral Process Movement Of Cell Or Subcellular Component Axon Development Rho Protein Signal Transduction Cellular Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Ras Protein Signal Transduction Regulation Of Cell Division
Tagcloud ?			adjacent ancts cancerous collectively concerning cytometric distant downregulation experiment immunohistochemical inducible invasion knockdown lentiviral metalloproteinase metastases metastasis microarray mmp mtt os osteosarcoma p65 pcna proliferating sirna transwell upregulation
Tagcloud (Difference) ?			adjacent ancts cancerous collectively concerning cytometric distant downregulation experiment immunohistochemical inducible invasion knockdown lentiviral metalloproteinase metastases metastasis microarray mmp mtt os osteosarcoma p65 pcna proliferating sirna transwell upregulation
Tagcloud (Intersection) ?