TNFAIP1 and HAT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TNFAIP1	HAT1
Description		TNF alpha induced protein 1	histone acetyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Cytosol Cul3-RING Ubiquitin Ligase Complex	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Cytoplasm Mitochondrion Nuclear Matrix Protein-containing Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Cyclin Binding Small GTPase Binding Identical Protein Binding	Histone Acetyltransferase Activity Protein Binding Histone H4 Acetyltransferase Activity Transferase Activity Acyltransferase Activity Histone Binding Histone H4K12 Acetyltransferase Activity Protein-lysine-acetyltransferase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Immune Response Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Protein Homooligomerization	Chromatin Organization Nucleosome Assembly Internal Protein Amino Acid Acetylation Subtelomeric Heterochromatin Formation Chromosome Organization
Pathways		RND3 GTPase cycle RND2 GTPase cycle	HATs acetylate histones
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 29403010) Osteoprotegerin levels ( 25080503)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Myopia ( 27182965) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		32 interacting genes: ARMC7 ARNT CAPN7 CARD9 CDC37 CSNK2B DAPP1 EPHA2 EPM2AIP1 EXOSC5 FXR1 FXR2 HAT1 HEXIM2 KDM1A LNX1 NTAQ1 NXF1 POLR1C PRKAG1 PSMA1 RHOA RHOB RIN3 SMARCA2 SMARCB1 STK16 SUV39H1 SVIL TRIM54 ZDHHC17 ZMYND19	23 interacting genes: ACAA1 CEBPA EZH2 H2AC20 H3-4 H3C1 H4C14 H4C16 HTR2B KANK4 MEOX2 MORN5 PRKAA2 REL SMAD7 SNAPC1 STEEP1 TCF4 TEPSIN TNFAIP1 TRIB3 YWHAQ ZSCAN4
Entrez ID		7126	8520
HPRD ID		01856	04339
Ensembl ID		ENSG00000109079	ENSG00000128708
Uniprot IDs		Q13829	A0AAG2UVM1 O14929
PDB IDs			2P0W 6VO5 9MJG
Enriched GO Terms of Interacting Partners?		Endothelial Tube Morphogenesis Protein Kinase Regulator Activity Regulation Of Modification Of Synaptic Structure Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Cleavage Furrow Positive Regulation Of Cell Development Regulation Of Generation Of Precursor Metabolites And Energy BBAF Complex Epigenetic Regulation Of Gene Expression Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Multicellular Organismal Development Brahma Complex NpBAF Complex Regulation Of Modification Of Postsynaptic Structure Costamere Cytoplasm NBAF Complex Regulation Of Endothelial Cell Migration Protein Binding Translation Regulator Activity Regulation Of Cell Cycle Regulation Of Cell Development Cytoplasmic Stress Granule Postsynapse Epithelial Tube Morphogenesis Positive Regulation Of Cell Differentiation Cytosol Nucleus Regulation Of DNA Repair Blastocyst Hatching Dentate Gyrus Development Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Cellular Component Size Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Nucleotide-excision Repair SWI/SNF Complex Positive Regulation Of T Cell Differentiation	Structural Constituent Of Chromatin Protein Heterodimerization Activity Nucleosome Chromosome, Telomeric Region Protein-DNA Complex Assembly DNA Binding Nucleosome Assembly Negative Regulation Of Chondrocyte Proliferation Negative Regulation Of Cell Differentiation Sequence-specific DNA Binding Chromatin Remodeling Chromosome Nucleosome Organization Telomere Organization Protein Localization To Chromatin Chromatin Organization Regulation Of Cell Differentiation Nucleus Nucleoplasm Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Developmental Process CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Stem Cell Differentiation Regulation Of Macromolecule Metabolic Process Protein Localization To Chromosome Protein-containing Complex Cardiac Muscle Hypertrophy Positive Regulation Of Proteasomal Protein Catabolic Process Muscle Hypertrophy Regulation Of Cell Development Positive Regulation Of Cartilage Development Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Metabolic Process Acetate CoA-transferase Activity Phenylacetate Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Hepatocyte Homeostasis Beta-catenin Destruction Complex Disassembly Positive Regulation Of Chondrocyte Hypertrophy Chromosome Organization Protein Localization To Chromosome, Centromeric Region Regulation Of Megakaryocyte Differentiation Coated Vesicle Membrane
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