TXNL1

Name	thioredoxin like 1
Structure
Interactors	6 interactors: CDC42 CEBPA HSPB1 PSMC3 SH3BP4 SUMO4
GO Annotations	Cellular Component	Proteasome Complex Nucleus Cytoplasm Cytosol
	Molecular Function	Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity
Pathways	RHOBTB2 GTPase cycle RHOU GTPase cycle RHOBTB1 GTPase cycle RHOV GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
GWAS	Cerebrospinal AB1-42 levels in normal cognition ( 29274321 ) Chronotype ( 30696823 ) Diverticular disease ( 30177863 ) General risk tolerance (MTAG) ( 30643258 ) Morning person ( 30696823 ) Number of sexual partners ( 30643258 ) Smoking status (ever vs never smokers) ( 30643258 ) Tourette's syndrome or obsessive-compulsive disorder ( 25158072 )
Entrez ID	9352
HPRD ID	04335
Ensembl ID	ENSG00000091164
Uniprot IDs	O43396 V9HW51
PDB IDs	1GH2 1WWY 9E8G 9E8H 9E8I 9E8J 9E8K 9E8L 9E8N 9E8O
GO Terms Enriched among Interactors ?	Host-mediated Perturbation Of Viral Process Macrophage Differentiation GBD Domain Binding Storage Vacuole Identical Protein Binding Modulation Of Process Of Another Organism Host-mediated Perturbation Of Symbiont Process Positive Regulation Of Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Protein Kinase C Signaling Proteasome Complex Endothelin Receptor Signaling Pathway Involved In Heart Process Myeloid Leukocyte Differentiation CHOP-C/EBP Complex Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Kinase C Inhibitor Activity Amino Acid Import Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway White Fat Cell Proliferation SUMO Ligase Complex Transport Along Microtubule Positive Regulation Of Pinocytosis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Regulation Of Intracellular Signal Transduction Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Positive Regulation Of Proteolysis Response To Phenylpropanoid RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Regulation Of Protein Kinase C Signaling Proteasome-activating Activity Establishment Of Golgi Localization Spindle Fat Cell Proliferation Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Myeloid Cell Differentiation Anterograde Axonal Protein Transport Leading Edge Membrane Thioesterase Binding Neuron Fate Determination