RYBP and GABPB2

Number of citations of the paper that reports this interaction (PMID 11953439)
9

Data Source:
BioGRID (pull down)

		RYBP	GABPB2
Gene Name		RING1 and YY1 binding protein	GA binding protein transcription factor, beta subunit 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm PcG Protein Complex	Nucleus
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding	Protein Homodimerization Activity Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Apoptotic Process Multicellular Organismal Development Histone H2A Monoubiquitination	Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Height ( 20881960 23563607)
Protein-Protein Interactions		17 interactors: ABL1 CASP10 CASP8 CBX2 E2F2 E2F3 E2F4 E2F6 FADD GABPB1 GABPB2 MDM2 RING1 RNF2 SOCS2 YY1 ZFP42	4 interactors: GORASP2 KDM1A RYBP ZDHHC17
Entrez ID		23429	126626
HPRD ID		09607	14536
Ensembl ID			ENSG00000143458
Uniprot IDs		Q8N488	Q5SZG2 Q8TAK5
PDB IDs		3IXS
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter TRAIL-activated Apoptotic Signaling Pathway RNA Metabolic Process Cell Cycle Gene Expression Apoptotic Signaling Pathway Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To UV-C Histone H2A Monoubiquitination Positive Regulation Of Macrophage Differentiation Negative Regulation Of Necroptotic Process Apoptotic Process Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Programmed Cell Death Negative Regulation Of Necrotic Cell Death Histone H2A Ubiquitination Positive Regulation Of Gene Expression Regulation Of Necroptotic Process Cell Death Death Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Histone Monoubiquitination Metabolic Process Organelle Organization Regulation Of Necrotic Cell Death Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter	Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Histone Modification Positive Regulation Of Megakaryocyte Differentiation Histone H2A Monoubiquitination Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Histone H2A Ubiquitination Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Lipoprotein Transport Positive Regulation Of Erythrocyte Differentiation Histone Monoubiquitination Magnesium Ion Transport Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Chromatin Modification Regulation Of Histone H3-K4 Methylation Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hormone Biosynthetic Process Protein Palmitoylation Chromatin Organization Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Lysine Demethylation Regulation Of Hormone Metabolic Process Histone Ubiquitination Histone Demethylation Regulation Of Erythrocyte Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Demethylation Protein Monoubiquitination Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of DNA Binding Organelle Organization Cellular Protein Modification Process Regulation Of Histone Methylation Positive Regulation Of Neural Precursor Cell Proliferation Pituitary Gland Development Negative Regulation Of Protein Binding Chromosome Organization Demethylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Stem Cell Proliferation
Tagcloud ?		3p amplifications breeding classic consuming cooperates costly daunting drive drivers driving endogenously engineering faithful foxp1 hidden incurable pc pten ptenloxp rapidcap recreate reside sensitized shq1 trp53 trp53loxp unmet validation	alkaline alp beta2 cytoplasm diffuse e26 establishing ets examining immunocytochemical immunoreactivity initially localized member mineralized nodule nuclei osteoblast osteoblastic osteogenic peaked phenotypic predominantly runx2 saos surmise synergy
Tagcloud (Difference) ?		3p amplifications breeding classic consuming cooperates costly daunting drive drivers driving endogenously engineering faithful foxp1 hidden incurable pc pten ptenloxp rapidcap recreate reside sensitized shq1 trp53 trp53loxp unmet validation	alkaline alp beta2 cytoplasm diffuse e26 establishing ets examining immunocytochemical immunoreactivity initially localized member mineralized nodule nuclei osteoblast osteoblastic osteogenic peaked phenotypic predominantly runx2 saos surmise synergy
Tagcloud (Intersection) ?