SLC7A8 and SLC3A2

Number of citations of the paper that reports this interaction (PMID 11311135)
6

Data Source:
HPRD (in vitro)

		SLC7A8	SLC3A2
Gene Name		solute carrier family 7 (amino acid transporter light chain, L system), member 8	solute carrier family 3 (amino acid transporter heavy chain), member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Apical Plasma Membrane Melanosome Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Organic Cation Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity Toxin Transporter Activity Peptide Antigen Binding	Double-stranded RNA Binding Catalytic Activity Calcium:sodium Antiporter Activity Protein Binding Neutral Amino Acid Transmembrane Transporter Activity Cation Binding Poly(A) RNA Binding
	Biological Process	Cellular Amino Acid Metabolic Process Transport Ion Transport Amino Acid Transport Blood Coagulation Response To Toxic Substance Organic Cation Transport Neutral Amino Acid Transport Leukocyte Migration Metal Ion Homeostasis Transmembrane Transport Toxin Transport L-alpha-amino Acid Transmembrane Transport	Carbohydrate Metabolic Process Ion Transport Calcium Ion Transport Amino Acid Transport Blood Coagulation Tryptophan Transport Cell Growth Sodium Ion Transmembrane Transport Response To Exogenous DsRNA Leukocyte Migration Transmembrane Transport Leucine Import
Pathways		Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane SLC-mediated transmembrane transport Basigin interactions Cell surface interactions at the vascular wall	Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane SLC-mediated transmembrane transport Basigin interactions Cell surface interactions at the vascular wall
Drugs		L-Phenylalanine L-Alanine
Diseases
GWAS
Protein-Protein Interactions		2 interactors: SLC3A1 SLC3A2	11 interactors: EGFR FAM57A HNRNPD ICAM1 ITGB1 SLC7A10 SLC7A11 SLC7A5 SLC7A7 SLC7A8 VHL
Entrez ID		23428	6520
HPRD ID		11971	01148
Ensembl ID		ENSG00000092068	ENSG00000168003
Uniprot IDs		Q53EM9 Q9UHI5	J3KPF3 P08195
PDB IDs			2DH2 2DH3
Enriched GO Terms of Interacting Partners?		Amino Acid Transmembrane Transport Amino Acid Transport Leucine Import Tryptophan Transport Carboxylic Acid Transport Organic Acid Transport Anion Transmembrane Transport Aromatic Amino Acid Transport Organic Anion Transport Leucine Transport L-cystine Transport Branched-chain Amino Acid Transport Anion Transport Amino Acid Import Basic Amino Acid Transport Carbohydrate Metabolic Process Ion Transmembrane Transport Neutral Amino Acid Transport Response To Exogenous DsRNA L-alpha-amino Acid Transmembrane Transport Transmembrane Transport Ion Transport Response To DsRNA Cell Growth Sodium Ion Transmembrane Transport Calcium Ion Transmembrane Transport Leukocyte Migration Sodium Ion Transport	Leukocyte Migration Cell Migration Cell Motility Amino Acid Transmembrane Transport Amino Acid Transport Locomotion Neutral Amino Acid Transport Blood Coagulation Hemostasis L-alpha-amino Acid Transmembrane Transport Movement Of Cell Or Subcellular Component Regulation Of Body Fluid Levels Wound Healing Carboxylic Acid Transport Organic Acid Transport Response To Wounding Immune System Process Response To Stress Anion Transmembrane Transport Organic Anion Transport Anion Transport Cell Adhesion Mediated By Integrin Single Organismal Cell-cell Adhesion Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Vasoconstriction Ion Transmembrane Transport Response To Gonadotropin Cell Activation Viral Entry Into Host Cell Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Entry Into Host Cell Rhythmic Process Regulation Of Vasoconstriction Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Cell Migration Chemical Homeostasis Positive Regulation Of Cell Motility Response To Organic Cyclic Compound Positive Regulation Of Cellular Component Movement Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Mechanical Stimulus Positive Regulation Of Locomotion Negative Regulation Of Apoptotic Process Transmembrane Transport Negative Regulation Of Programmed Cell Death Ion Transport Alkanesulfonate Metabolic Process Response To Sulfur Dioxide D-alanine Transport
Tagcloud ?		4f2hc aaas aas aminoaciduria antiporter aromatic basolateral compensatory enterocytes equilibrate everted gross grow gut instance intestine intravenously lat2 myocytes phe presumably reproduce sac sink slc16a10 tat1 transported tubule uniporter	adenocarcinoma anchorage approved braf cd74 consisting constitutively driver druggable erbb4 exclusively ezr fusion fusions her3 ima imas kiaa1468 kras mucinous mutually nih3t3 nrg1 oncogenic ret sequencing transcriptome trim24 tumorigenicity
Tagcloud (Difference) ?		4f2hc aaas aas aminoaciduria antiporter aromatic basolateral compensatory enterocytes equilibrate everted gross grow gut instance intestine intravenously lat2 myocytes phe presumably reproduce sac sink slc16a10 tat1 transported tubule uniporter	adenocarcinoma anchorage approved braf cd74 consisting constitutively driver druggable erbb4 exclusively ezr fusion fusions her3 ima imas kiaa1468 kras mucinous mutually nih3t3 nrg1 oncogenic ret sequencing transcriptome trim24 tumorigenicity
Tagcloud (Intersection) ?