SLC7A8 and SLC3A1

Number of citations of the paper that reports this interaction (PMID 10574970)
39

Data Source:
HPRD (in vivo)

		SLC7A8	SLC3A1
Gene Name		solute carrier family 7 (amino acid transporter light chain, L system), member 8	solute carrier family 3 (amino acid transporter heavy chain), member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Extracellular Vesicular Exosome	Mitochondrial Inner Membrane Vacuolar Membrane Plasma Membrane Integral Component Of Plasma Membrane Membrane Brush Border Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Organic Cation Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity Toxin Transporter Activity Peptide Antigen Binding	Catalytic Activity Protein Binding Amino Acid Transmembrane Transporter Activity Basic Amino Acid Transmembrane Transporter Activity L-cystine Transmembrane Transporter Activity Cation Binding Protein Heterodimerization Activity
	Biological Process	Cellular Amino Acid Metabolic Process Transport Ion Transport Amino Acid Transport Blood Coagulation Response To Toxic Substance Organic Cation Transport Neutral Amino Acid Transport Leukocyte Migration Metal Ion Homeostasis Transmembrane Transport Toxin Transport L-alpha-amino Acid Transmembrane Transport	Amino Acid Transmembrane Transport Carbohydrate Metabolic Process Cellular Amino Acid Metabolic Process Ion Transport Amino Acid Transport Basic Amino Acid Transport L-cystine Transport Transmembrane Transport
Pathways		Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane SLC-mediated transmembrane transport Basigin interactions Cell surface interactions at the vascular wall	Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane SLC-mediated transmembrane transport
Drugs		L-Phenylalanine L-Alanine	L-Cystine
Diseases
GWAS
Protein-Protein Interactions		2 interactors: SLC3A1 SLC3A2	1 interactors: SLC7A8
Entrez ID		23428	6519
HPRD ID		11971	00090
Ensembl ID		ENSG00000092068
Uniprot IDs		Q53EM9 Q9UHI5	Q07837
PDB IDs
Enriched GO Terms of Interacting Partners?		Amino Acid Transmembrane Transport Amino Acid Transport Leucine Import Tryptophan Transport Carboxylic Acid Transport Organic Acid Transport Anion Transmembrane Transport Aromatic Amino Acid Transport Organic Anion Transport Leucine Transport L-cystine Transport Branched-chain Amino Acid Transport Anion Transport Amino Acid Import Basic Amino Acid Transport Carbohydrate Metabolic Process Ion Transmembrane Transport Neutral Amino Acid Transport Response To Exogenous DsRNA L-alpha-amino Acid Transmembrane Transport Transmembrane Transport Ion Transport Response To DsRNA Cell Growth Sodium Ion Transmembrane Transport Calcium Ion Transmembrane Transport Leukocyte Migration Sodium Ion Transport	Toxin Transport Organic Cation Transport Neutral Amino Acid Transport L-alpha-amino Acid Transmembrane Transport Amino Acid Transmembrane Transport Amino Acid Transport Response To Toxic Substance
Tagcloud ?		4f2hc aaas aas aminoaciduria antiporter aromatic basolateral compensatory enterocytes equilibrate everted gross grow gut instance intestine intravenously lat2 myocytes phe presumably reproduce sac sink slc16a10 tat1 transported tubule uniporter	2p16 aminoaciduria amplified another autosomal base belgian coding comprising cystinuria deletions described detect dscr1 entire exon exons fluorescent located making missing multiplex named rbat recessive scanning semi ten transporter
Tagcloud (Difference) ?		4f2hc aaas aas antiporter aromatic basolateral compensatory enterocytes equilibrate everted gross grow gut instance intestine intravenously lat2 myocytes phe presumably reproduce sac sink slc16a10 tat1 transported tubule uniporter	2p16 amplified another autosomal base belgian coding comprising cystinuria deletions described detect dscr1 entire exon exons fluorescent located making missing multiplex named rbat recessive scanning semi ten transporter
Tagcloud (Intersection) ?		aminoaciduria