SLC7A8 and SLC3A1

Number of citations of the paper that reports this interaction (PubMedID 10574970)
0

Data Source:
HPRD (in vivo)

		SLC7A8	SLC3A1
Description		solute carrier family 7 member 8	solute carrier family 3 member 1
Image
GO Annotations	Cellular Component	Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Microvillus Membrane	Vacuolar Membrane Plasma Membrane Membrane Apical Plasma Membrane Brush Border Membrane Extracellular Exosome
	Molecular Function	Protein Binding Organic Cation Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity Glycine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity Antiporter Activity Thyroid Hormone Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity Transmembrane Transporter Activity Peptide Antigen Binding Protein Heterodimerization Activity	Protein Binding Amino Acid Transmembrane Transporter Activity Basic Amino Acid Transmembrane Transporter Activity L-cystine Transmembrane Transporter Activity Protein-containing Complex Binding Protein Heterodimerization Activity
	Biological Process	Amino Acid Transmembrane Transport Amino Acid Transport Neutral Amino Acid Transport L-amino Acid Transport Glycine Transport L-leucine Transport Tryptophan Transport Valine Transport Proline Transmembrane Transport Transmembrane Transport Thyroid Hormone Transport Amino Acid Import Across Plasma Membrane Transport Across Blood-brain Barrier L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane	Carbohydrate Metabolic Process Amino Acid Transport Gene Expression Basic Amino Acid Transport Aspartate Transmembrane Transport L-cystine Transport L-glutamate Transmembrane Transport Basic Amino Acid Transmembrane Transport
Pathways		Basigin interactions Amino acid transport across the plasma membrane	Amino acid transport across the plasma membrane Defective SLC3A1 causes cystinuria (CSNU) Defective SLC7A9 causes cystinuria (CSNU)
Drugs		Phenylalanine Alanine
Diseases			Cystinuria
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847)	antipsychotic drug dosage in schizophrenia or schizoaffective disorder ( 26821981) Refractive error ( 32231278)
Interacting Genes		26 interacting genes: ABHD16A AGPAT4 AQP6 COMT DERL1 FXYD6-FXYD2 MFF NDUFA3 NINJ2 REEP4 SIGLEC5 SLC25A46 SLC30A2 SLC33A2 SLC3A1 SLC3A2 SMPD2 SNORC SYCE1L SYNJ2BP TMEM14B TMEM208 TMEM60 TMEM65 YIPF1 YIPF6	1 interacting genes: SLC7A8
Entrez ID		23428	6519
HPRD ID		11971	00090
Ensembl ID		ENSG00000092068	ENSG00000138079
Uniprot IDs		Q53EM9 Q9UHI5	A0A0S2Z4E1 B8ZZK1 Q07837
PDB IDs		7B00 7CMH 7CMI 8A6L	6LI9 6LID 6YUP 6YUZ
Enriched GO Terms of Interacting Partners?		Membrane Golgi Trans Cisterna Golgi Medial Cisterna Sulfur Amino Acid Transport Mitochondrial Fission Mitochondrial Outer Membrane Basic Amino Acid Transport	Postsynaptic Density Assembly Axonogenesis Involved In Innervation Mitochondrial Fragmentation Involved In Apoptotic Process Postsynaptic Specialization Assembly L-alanine Transport Tryptophan Transport Branched-chain Amino Acid Transport Proline Transmembrane Transport Organic Cation Transmembrane Transporter Activity Aromatic Amino Acid Transport L-alanine Transmembrane Transport L-leucine Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity L-leucine Transport L-leucine Import Across Plasma Membrane Glycine Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-alanine Import Across Plasma Membrane Thyroid Hormone Transmembrane Transporter Activity Valine Transport Thyroid Hormone Transport Glycine Transport Cellular Response To Potassium Ion L-amino Acid Transmembrane Transporter Activity Alanine Transport Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Postsynaptic Density Organization Neutral L-amino Acid Transmembrane Transporter Activity Response To Potassium Ion Synaptic Cleft Postsynaptic Specialization Organization Microvillus Membrane Amino Acid Transmembrane Transporter Activity Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Mitochondrial Transport Amino Acid Import Across Plasma Membrane Peptide Antigen Binding Neutral Amino Acid Transport Receptor Localization To Synapse L-alpha-amino Acid Transmembrane Transport Protein Localization To Synapse Cellular Response To Glucose Stimulus Protein-containing Complex Localization Apoptotic Mitochondrial Changes Basal Plasma Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels L-amino Acid Transport Cellular Response To Carbohydrate Stimulus Transport Across Blood-brain Barrier
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