SLC7A8 and TMEM208

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC7A8	TMEM208
Description		solute carrier family 7 member 8	transmembrane protein 208
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Microvillus Membrane	Vacuole Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Organic Cation Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity Glycine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity Antiporter Activity Thyroid Hormone Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity Transmembrane Transporter Activity Peptide Antigen Binding Protein Heterodimerization Activity	Protein Binding
	Biological Process	Amino Acid Transmembrane Transport Amino Acid Transport Neutral Amino Acid Transport L-amino Acid Transport Glycine Transport L-leucine Transport Tryptophan Transport Valine Transport Proline Transmembrane Transport Transmembrane Transport Thyroid Hormone Transport Amino Acid Import Across Plasma Membrane Transport Across Blood-brain Barrier L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane	Vacuolar Protein Processing Autophagy
Pathways		Basigin interactions Amino acid transport across the plasma membrane
Drugs		Phenylalanine Alanine
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		26 interacting genes: ABHD16A AGPAT4 AQP6 COMT DERL1 FXYD6-FXYD2 MFF NDUFA3 NINJ2 REEP4 SIGLEC5 SLC25A46 SLC30A2 SLC33A2 SLC3A1 SLC3A2 SMPD2 SNORC SYCE1L SYNJ2BP TMEM14B TMEM208 TMEM60 TMEM65 YIPF1 YIPF6	23 interacting genes: C10orf67 CREB3L1 EBP FAM209A GPR152 GPRC5D KCNJ6 LMNA NDRG4 PGRMC2 REEP2 REEP4 RNF19B SCARA5 SCN3B SLC10A6 SLC30A8 SLC71A2 SLC7A8 SPG21 STOM TMEM31 TMX2
Entrez ID		23428	29100
HPRD ID		11971	13710
Ensembl ID		ENSG00000092068	ENSG00000168701
Uniprot IDs		Q53EM9 Q9UHI5	J3KRY7 Q9BTX3
PDB IDs		7B00 7CMH 7CMI 8A6L
Enriched GO Terms of Interacting Partners?		Membrane Golgi Trans Cisterna Golgi Medial Cisterna Sulfur Amino Acid Transport Mitochondrial Fission Mitochondrial Outer Membrane Basic Amino Acid Transport	Membrane Monoatomic Cation Transport Metal Ion Transport Nuclear Envelope Organization Endoplasmic Reticulum Membrane Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization
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