SLC3A2 and SLC7A11

Number of citations of the paper that reports this interaction (PubMedID 11406111)
0

Data Source:
HPRD (in vivo)

		SLC3A2	SLC7A11
Description		solute carrier family 3 member 2	solute carrier family 7 member 11
Image
GO Annotations	Cellular Component	Nucleoplasm Lysosome Lysosomal Membrane Plasma Membrane Basal Plasma Membrane Cell Surface Membrane Basolateral Plasma Membrane Apical Plasma Membrane Melanosome Neuronal Cell Body Apical Pole Of Neuron Synapse Extracellular Exosome Anchoring Junction Amino Acid Transport Complex	Plasma Membrane Cell Surface Membrane Brush Border Membrane Microvillus Membrane Cell Projection Apical Part Of Cell Astrocyte Projection
	Molecular Function	Virus Receptor Activity RNA Binding Double-stranded RNA Binding Protein Binding Aromatic Amino Acid Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Exogenous Protein Binding	Protein Binding L-amino Acid Transmembrane Transporter Activity Cystine:glutamate Antiporter Activity Transmembrane Transporter Activity L-kynurenine Transmembrane Transporter Activity
	Biological Process	Carbohydrate Metabolic Process Calcium Ion Transport Amino Acid Transport Isoleucine Transport L-leucine Transport Methionine Transport Phenylalanine Transport Proline Transport Tryptophan Transport Tyrosine Transport Valine Transport Response To Exogenous DsRNA Symbiont Entry Into Host Cell Thyroid Hormone Transport L-histidine Transport L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane	Amino Acid Transmembrane Transport Glutathione Metabolic Process Amino Acid Transport Brain Development Visual Learning Response To Toxic Substance L-cystine Transport L-glutamate Transmembrane Transport Ventricular System Development Striatum Development Adult Behavior Regulation Of Neutrophil Apoptotic Process Cellular Response To Stress Cellular Response To Oxidative Stress Glutathione Transmembrane Transport Regulation Of Cell Population Proliferation Regulation Of Programmed Cell Death Regulation Of Melanin Biosynthetic Process Lung Alveolus Development Modulation Of Chemical Synaptic Transmission Regulation Of Synapse Organization Regulation Of Protein Transport Response To Redox State Transmembrane Transport Limb Development Platelet Aggregation Intracellular Glutamate Homeostasis L-glutamate Import Across Plasma Membrane Negative Regulation Of Ferroptosis Dipeptide Import Across Plasma Membrane L-kynurenine Transmembrane Transport Regulation Of Cellular Response To Oxidative Stress Regulation Of Cysteine Metabolic Process Regulation Of Glutathione Biosynthetic Process Regulation Of AMPA Glutamate Receptor Clustering Regulation Of Glutamate Metabolic Process
Pathways		Basigin interactions Amino acid transport across the plasma membrane Defective SLC7A7 causes lysinuric protein intolerance (LPI) Tryptophan catabolism	Basigin interactions Amino acid transport across the plasma membrane NFE2L2 regulating anti-oxidant/detoxification enzymes
Drugs			Cystine Glutamic acid Riluzole Sulfasalazine Acetylcysteine Thimerosal
Diseases
GWAS		Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Mood instability ( 31168069) Neurociticism ( 29500382) Sleep duration (> 10 hours) ( 33075057)
Interacting Genes		18 interacting genes: CCR4 CEBPA EBP EGFR GPR37 HNRNPD ICAM1 ITGB1 KLHL20 MTNR1B NPSR1 SLC7A10 SLC7A11 SLC7A5 SLC7A7 SLC7A8 TLCD3A VHL	7 interacting genes: BAAT KRTAP1-1 KRTAP1-3 PCBP2 SLC3A2 TERT ZRANB1
Entrez ID		6520	23657
HPRD ID		01148	09720
Ensembl ID		ENSG00000168003	ENSG00000151012
Uniprot IDs		P08195	Q9UPY5
PDB IDs		2DH2 2DH3 6IRS 6IRT 6JMQ 6JMR 6S8V 7B00 7CCS 7CMH 7CMI 7DF1 7DSK 7DSL 7DSN 7DSQ 7EPZ 7P9U 7P9V 8A6L 8G0M 8IDA 8J8L 8J8M 8KDD 8KDF 8KDG 8KDH 8KDI 8KDJ 8KDN 8KDO 8KDP 8QEY 8WNS 8WNT 8WNY 8X0W 8XPU 8YLP	7CCS 7EPZ 7P9U 7P9V
Enriched GO Terms of Interacting Partners?		L-amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transport L-alpha-amino Acid Transmembrane Transport L-amino Acid Transport Amino Acid Transmembrane Transport Negative Regulation Of Programmed Cell Death Amino Acid Transport Branched-chain Amino Acid Transport L-leucine Transport Organic Acid Transmembrane Transport Carboxylic Acid Transmembrane Transport Alanine Transport Neutral L-amino Acid Transmembrane Transporter Activity Transmembrane Transporter Activity Negative Regulation Of Apoptotic Process Organic Cation Transport L-leucine Import Across Plasma Membrane Microvillus Membrane Liver Development Response To Amino Acid Regulation Of Apoptotic Process Amino Acid Import Across Plasma Membrane Carboxylic Acid Transport Organic Acid Transport Valine Transport Regulation Of Programmed Cell Death L-leucine Transmembrane Transporter Activity Tryptophan Transport Plasma Membrane Thyroid Hormone Transmembrane Transporter Activity Organic Anion Transport Negative Regulation Of Catabolic Process Basal Plasma Membrane Aromatic Amino Acid Transport Thyroid Hormone Transport Organic Cation Transmembrane Transporter Activity Animal Organ Development Glycine Transport Negative Regulation Of Vasoconstriction Cellular Response To Amino Acid Stimulus Virus Receptor Activity Sulfur Amino Acid Transport Basolateral Plasma Membrane Vascular Process In Circulatory System Neuropeptide Signaling Pathway Learning Or Memory Gland Development Neuropeptide Receptor Activity Basic Amino Acid Transport Response To Cytokine	Glycine N-choloyltransferase Activity Bile Acid Conjugation Apical Pole Of Neuron TERT-RMRP Complex Template-free RNA Nucleotidyltransferase Positive Regulation Of Transdifferentiation RNA-directed RNA Polymerase Complex SiRNA Transcription Medium-chain Fatty Acyl-CoA Hydrolase Activity Choloyl-CoA Hydrolase Activity Very Long-chain Fatty Acyl-CoA Hydrolase Activity Exogenous Protein Binding Amino Acid Transport Complex Positive Regulation Of Hair Cycle Telomerase Catalytic Core Complex Keratin Filament Methionine Transport L-leucine Import Across Plasma Membrane Aromatic Amino Acid Transmembrane Transporter Activity Tyrosine Transport RNA-directed RNA Polymerase Activity RNA-templated Transcription RNA-directed DNA Polymerase Activity L-histidine Transport Phenylalanine Transport Valine Transport L-alanine Import Across Plasma Membrane Positive Regulation Of Wnt Signaling Pathway Protein K29-linked Deubiquitination Isoleucine Transport L-leucine Transmembrane Transporter Activity L-alanine Transmembrane Transport Tryptophan Transport Protein K33-linked Deubiquitination Intermediate Filament Promoter-enhancer Loop Anchoring Activity L-alanine Transmembrane Transporter Activity Positive Regulation Of Protein Localization To Nucleolus Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Viral RNA Genome Replication Telomerase Activity Establishment Of Protein Localization To Telomere L-alanine Transport SiRNA Processing N-acyltransferase Activity Thiolester Hydrolase Activity L-leucine Transport Proline Transport Nuclear Telomere Cap Complex Taurine Metabolic Process
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